PM20D2 and TDO2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PM20D2	TDO2
Description		peptidase M20 domain containing 2	tryptophan 2,3-dioxygenase
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Cytosol
	Molecular Function	Carboxypeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity Dipeptidase Activity Identical Protein Binding Para-aminobenzoyl-glutamate Hydrolase Activity	Tryptophan 2,3-dioxygenase Activity Protein Binding Oxidoreductase Activity Amino Acid Binding Oxygen Binding Heme Binding Identical Protein Binding Metal Ion Binding Dioxygenase Activity
	Biological Process	Proteolysis Folic Acid Catabolic Process Regulation Of Protein Metabolic Process	L-tryptophan Metabolic Process L-tryptophan Catabolic Process L-tryptophan Catabolic Process To Kynurenine L-tryptophan Catabolic Process To Acetyl-CoA Protein Homotetramerization Response To Nitroglycerin
Pathways			Tryptophan catabolism
Drugs
Diseases
GWAS		Serum metabolite levels ( 33031748)	Manganese levels ( 26025379) Speech perception in dyslexia ( 19786962)
Interacting Genes		24 interacting genes: CERT1 CNNM3 DALRD3 DDIT4L DNAJC11 EPDR1 HAPLN2 KEL KRT75 KRTAP26-1 MEOX1 MYOZ3 NAA80 OGT POU6F2 PSMA1 REL RGS12 RP2 RUSC1 SAXO1 SIVA1 TAPBPL TDO2	20 interacting genes: ASMTL DPM1 EIF4E KDM1A LMNA LNX1 MEOX2 MOB1A MOB3C NGB NMNAT1 NR1D1 PICK1 PM20D2 PRMT6 PSMA1 REL SDCBP SDCBP2 ZFYVE26
Entrez ID		135293	6999
HPRD ID		16473	01847
Ensembl ID		ENSG00000146281	ENSG00000151790
Uniprot IDs		Q8IYS1	P48775
PDB IDs		7YH4 8XZC	4PW8 5TI9 5TIA 6A4I 6PYY 6PYZ 6UD5 6VBN 7LU7 7UI3 8QV7 8R5Q 8R5R 8VTQ 8VUG 8VZV 8W1H 8W2K 9AT2 9B17 9B1Q 9EZJ
Enriched GO Terms of Interacting Partners?
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