PM20D2 and EPDR1

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		PM20D2	EPDR1
Description		peptidase M20 domain containing 2	ependymin related 1
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GO Annotations	Cellular Component	Nucleoplasm Cytoplasm	Extracellular Region Lysosome Lysosomal Lumen
	Molecular Function	Carboxypeptidase Activity Protein Binding Peptidase Activity Hydrolase Activity Dipeptidase Activity Identical Protein Binding Para-aminobenzoyl-glutamate Hydrolase Activity	Calcium Ion Binding Protein Binding Phospholipid Binding Lipid Binding Identical Protein Binding Ganglioside GM1 Binding
	Biological Process	Proteolysis Folic Acid Catabolic Process Regulation Of Protein Metabolic Process	Cell-matrix Adhesion Myofibroblast Contraction
Pathways
Drugs
Diseases
GWAS		Serum metabolite levels ( 33031748)	Dupuytren's disease ( 21732829 28886342) Glaucoma (primary angle closure) ( 27064256) Heel bone mineral density ( 28869591 30598549) Height ( 31562340) Lateral ventricle volume ( 31530798) Lumbar spine bone mineral density ( 29499414) Rosacea symptom severity ( 29771307)
Interacting Genes		24 interacting genes: CERT1 CNNM3 DALRD3 DDIT4L DNAJC11 EPDR1 HAPLN2 KEL KRT75 KRTAP26-1 MEOX1 MYOZ3 NAA80 OGT POU6F2 PSMA1 REL RGS12 RP2 RUSC1 SAXO1 SIVA1 TAPBPL TDO2	13 interacting genes: ADAMTSL4 EHMT2 HOXA1 IGFBP6 KRT31 KRT34 KRTAP10-8 KRTAP13-2 KRTAP4-11 PM20D2 TNS2 TRIP6 UBQLN4
Entrez ID		135293	54749
HPRD ID		16473	16865
Ensembl ID		ENSG00000146281	ENSG00000086289
Uniprot IDs		Q8IYS1	Q96J80 Q9UM22
PDB IDs		7YH4 8XZC	6E7O 6E8N 6JLD
Enriched GO Terms of Interacting Partners?			Keratin Filament Intermediate Filament Identical Protein Binding Structural Molecule Activity Negative Regulation Of Macroautophagy Semicircular Canal Formation Insulin-like Growth Factor Binary Complex Histone H3K56 Methyltransferase Activity Pigment Cell Development Para-aminobenzoyl-glutamate Hydrolase Activity Structural Constituent Of Skin Epidermis Abducens Nerve Formation Optokinetic Behavior Intermediate Filament Organization Nuclear Proteasome Complex Folic Acid Catabolic Process Intermediate Filament Cytoskeleton Organization Intermediate Filament-based Process Phenotypic Switching Negative Regulation Of Autophagosome Maturation Kinase Binding Negative Regulation Of Autophagy
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