SIRT1 and SREBF1

  • Number of citations of the paper that reports this interaction (PMID 20595232)
  • 72
  • Data Source:
  • BioGRID (enzymatic study)

SIRT1

SREBF1

Gene Name sirtuin 1 sterol regulatory element binding transcription factor 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 47 interactors: AKT1 ARNTL BCL11A BHLHE41 CDK6 CSNK2B CTTN EP300 ESRRA FOS FOXO1 FOXO3 GAPDH HES1 HEY2 HIC1 HIST1H1B HIST1H3A HNF4A IRS2 MAPK8 MAPT MYCN NBN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARGC1A PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 SREBF1 STK11 STK4 TP53 UBE2I VDR 35 interactors: AR ATXN1 ATXN1L CDK8 CREBBP ESR1 ESR2 GSK3B HNF4A ID3 KLF13 LMNA MAPK1 MAPK3 MED1 MED12 MED13 MED14 MED17 MED23 MED24 MED25 MED26 MED6 MED7 NR0B1 SIRT1 SMARCD3 SP1 SREBF2 SUMO1 TWIST2 UBE2I YY1 ZBTB7C
Entrez ID 23411 6720
HPRD ID 08381 01701
Ensembl ID ENSG00000096717 ENSG00000072310
Uniprot IDs A8K128 B0QZ35 E9PC49 Q96EB6 B4DEU6 P36956
PDB IDs 4I5I 1AM9
Enriched GO Terms of Interacting Partners?
Tagcloud ?
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
aberrations  acly  biphasic  cascade  chemoprevention  citrate  desaturase  disturbed  fads2  fatty  harboring  hbv  hcc  hepatocytes  lipid  livers  lyase  metabolism  mtor  pre  remarkably  s2  starting  sterol  subsided  synchronized  transgenic  tumorigenesis  upregulate 
Tagcloud (Difference) ?
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  identifies  links  lipase  lipolysis  mediates  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
aberrations  acly  biphasic  cascade  chemoprevention  citrate  desaturase  disturbed  fads2  harboring  hbv  hcc  hepatocytes  lipid  livers  lyase  mtor  pre  remarkably  s2  starting  sterol  subsided  synchronized  transgenic  tumorigenesis  upregulate 
Tagcloud (Intersection) ?
fatty  metabolism