MED23 and FOXJ3

Number of citations of the paper that reports this interaction (PubMedID 12421765)
39

Data Source:
HPRD (two hybrid)

		MED23	FOXJ3
Description		mediator complex subunit 23	forkhead box J3
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Mediator Complex Core Mediator Complex	Chromatin Nucleus
	Molecular Function	Transcription Coactivator Activity Protein Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Sequence-specific DNA Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Transcription Initiation At RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription Elongation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II Positive Regulation Of T Cell Extravasation	Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Male Meiosis I Spermatogenesis Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Meiotic Cell Cycle
Pathways		PPARA activates gene expression Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Transcriptional regulation of white adipocyte differentiation RSV-host interactions MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		L-arginine levels ( 25245031) Type 2 diabetes ( 30054458)
Interacting Genes		17 interacting genes: CEBPA CEBPB CTDP1 ELF3 ESR1 ESR2 ETS1 FOXJ3 MED13 MED9 NCOA6 PUM2 RELA SREBF1 VDR WDTC1 WEE2-AS1	5 interacting genes: MED23 MED4 NEDD4 NEK6 YAP1
Entrez ID		9439	22887
HPRD ID		05436	13549
Ensembl ID		ENSG00000112282	ENSG00000198815
Uniprot IDs		Q05DL5 Q9ULK4	Q9UPW0
PDB IDs		6H02 7EMF 7ENA 7ENC 7ENJ 7LBM 8GXQ 8GXS 8T9D 8TQW 8TRH
Enriched GO Terms of Interacting Partners?		Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Factor Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Positive Regulation Of Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Metabolic Process Chromatin DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Macromolecule Metabolic Process Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Metabolic Process Nuclear Receptor Activity Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Macromolecule Metabolic Process C/EBP Complex Regulation Of MiRNA Transcription Nucleoplasm Nuclear Steroid Receptor Activity Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of MiRNA Metabolic Process Negative Regulation Of Biosynthetic Process Intracellular Receptor Signaling Pathway CHOP-C/EBP Complex RNA Metabolic Process Macromolecule Biosynthetic Process Nuclear Estrogen Receptor Activity Mammary Gland Branching Involved In Pregnancy Chromatin Binding Histone Deacetylase Binding Response To Lipid Negative Regulation Of Macromolecule Metabolic Process	Proline-rich Region Binding Core Mediator Complex Transcription Coactivator Activity Mediator Complex Mesenchyme Development Positive Regulation Of DNA-templated Transcription, Elongation Transcription Preinitiation Complex Assembly Positive Regulation Of Transcription Initiation By RNA Polymerase II RNA Polymerase II Preinitiation Complex Assembly Positive Regulation Of Transcription Elongation By RNA Polymerase II Positive Regulation Of DNA-templated Transcription Initiation Regulation Of Transcription Initiation By RNA Polymerase II Regulation Of DNA-templated Transcription Initiation Formation Of Structure Involved In A Symbiotic Process Regulation Of Transcription Elongation By RNA Polymerase II Enterocyte Differentiation Regulation Of DNA-templated Transcription Elongation Transcription Coregulator Activity Channel Inhibitor Activity Nucleoplasm Phosphothreonine Residue Binding TEAD-YAP Complex Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Cellular Response To Radiation Nucleobase-containing Compound Biosynthetic Process Positive Regulation Of T Cell Extravasation Protein-DNA Complex Assembly Lateral Mesoderm Development Cardiac Muscle Tissue Regeneration DNA-binding Transcription Factor Binding Nuclear Receptor-mediated Corticosteroid Signaling Pathway Phosphoserine Residue Binding Beta-2 Adrenergic Receptor Binding Negative Regulation Of Potassium Ion Export Across Plasma Membrane Cellular Component Assembly Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Regulation Of Transcription By RNA Polymerase II Transcription Regulator Complex Bud Elongation Involved In Lung Branching Nucleobase-containing Compound Metabolic Process Sodium Channel Inhibitor Activity Paraxial Mesoderm Development Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Tube Morphogenesis Regulation Of Potassium Ion Export Across Plasma Membrane Progesterone Receptor Signaling Pathway Transcription By RNA Polymerase II Potassium Channel Inhibitor Activity Protein-containing Complex Assembly Positive Regulation Of Transcription By RNA Polymerase II
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