DAZL and DAZ4

Number of citations of the paper that reports this interaction (PubMedID 12511597)
35

Data Source:
HPRD (two hybrid)

		DAZL	DAZ4
Description		deleted in azoospermia like	deleted in azoospermia 4
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Ribosome Protein-containing Complex	Nucleus Cytoplasm Protein-containing Complex
	Molecular Function	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity Identical Protein Binding	Nucleic Acid Binding RNA Binding MRNA 3'-UTR Binding Protein Binding Translation Activator Activity
	Biological Process	Oocyte Maturation Regulation Of Translation Female Meiosis II Germ Cell Development Spermatogenesis Cell Differentiation Positive Regulation Of Meiotic Nuclear Division Positive Regulation Of Translational Initiation 3'-UTR-mediated MRNA Stabilization	Spermatogenesis Cell Differentiation Positive Regulation Of Translational Initiation 3'-UTR-mediated MRNA Stabilization
Pathways
Drugs
Diseases
GWAS		Feeling fed-up ( 29500382) Intelligence ( 28530673) Lung cancer ( 28604730) Metabolite levels ( 23823483) Night sleep phenotypes ( 27126917) Smoking initiation ( 33082346) Testicular germ cell tumor ( 23666240 25877299 28604728 28604732)
Interacting Genes		5 interacting genes: DAZ1 DAZ4 DAZAP1 DAZAP2 PUM2	6 interacting genes: BOLL CFTR DAZL DZIP1 PUM2 QKI
Entrez ID		1618	57135
HPRD ID		09029	13117
Ensembl ID		ENSG00000092345	ENSG00000205916
Uniprot IDs		A0A140VK77 Q92904	A0A804HKV4 Q86SG3
PDB IDs
Enriched GO Terms of Interacting Partners?		MRNA 3'-UTR Binding Regulation Of MRNA Metabolic Process Translation Activator Activity Regulation Of MRNA Stability Regulation Of RNA Stability 3'-UTR-mediated MRNA Stabilization Protein-containing Complex Stress Granule Assembly Positive Regulation Of Translational Initiation Regulation Of Translation MRNA Stabilization Male Gamete Generation Positive Regulation Of Macromolecule Metabolic Process Negative Regulation Of MRNA Catabolic Process Spermatogenesis RNA Stabilization RNA Binding Gamete Generation Negative Regulation Of RNA Catabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Cytoplasmic Stress Granule Pumilio-response Element Binding Negative Regulation Of MRNA Metabolic Process Nucleic Acid Binding Regulation Of Translational Initiation Post-transcriptional Regulation Of Gene Expression Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Sprouting Of Injured Axon Positive Regulation Of MRNA Metabolic Process Positive Regulation Of Translation Developmental Process Involved In Reproduction Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Intracellular MRNA Localization Regulation Of Primary Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Biological Quality Poly(G) Binding Positive Regulation Of Biosynthetic Process Membraneless Organelle Assembly Positive Regulation Of Axon Regeneration Maternal Placenta Development Regulation Of Macromolecule Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of RIG-I Signaling Pathway Positive Regulation Of MiRNA-mediated Gene Silencing Reproductive Process Negative Regulation Of Catabolic Process Mitogen-activated Protein Kinase Kinase Kinase Binding	MRNA 3'-UTR Binding Regulation Of MRNA Stability Regulation Of RNA Stability MRNA Stabilization Developmental Process Involved In Reproduction Negative Regulation Of MRNA Catabolic Process Regulation Of MRNA Metabolic Process RNA Stabilization Negative Regulation Of RNA Catabolic Process Negative Regulation Of MRNA Metabolic Process Regulation Of Translation Translation Activator Activity Reproductive Process 3'-UTR-mediated MRNA Stabilization Post-transcriptional Regulation Of Gene Expression Germ Cell Development Stress Granule Assembly MiRNA Binding Positive Regulation Of Translational Initiation Negative Regulation Of Catabolic Process Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Internal N(7)-methylguanine-containing RNA Reader Activity Pumilio-response Element Binding Regulation Of Biological Quality Male Gamete Generation Spermatogenesis Cytoplasmic Stress Granule Positive Regulation Of Anion Channel Activity Cellular Developmental Process Developmental Process Regulation Of Translational Initiation Female Meiosis II Gamete Generation Nucleic Acid Binding Myofibroblast Contraction Positive Regulation Of MRNA Catabolic Process Negative Regulation Of MiRNA Catabolic Process BBSome Binding Protein-containing Complex Localization To Centriolar Satellite Positive Regulation Of Sprouting Of Injured Axon RNA Binding Regulation Of Protein Metabolic Process Positive Regulation Of Monoatomic Anion Transport Positive Regulation Of MRNA Metabolic Process Cell Maturation Positive Regulation Of Translation Organelle Assembly Positive Regulation Of Enamel Mineralization
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