DNAJC13 and RPS6KA6

Number of citations of the paper that reports this interaction (PMID 21900206)
27

Data Source:
BioGRID (two hybrid)

		DNAJC13	RPS6KA6
Gene Name		DnaJ (Hsp40) homolog, subfamily C, member 13	ribosomal protein S6 kinase, 90kDa, polypeptide 6
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Lysosomal Membrane Endosome Membrane Membrane Early Endosome Membrane Extracellular Vesicular Exosome WASH Complex	Nucleus Nucleoplasm Nucleolus Mitochondrion Cytosol
	Molecular Function	Protein Binding	Magnesium Ion Binding Protein Kinase Activity Protein Serine/threonine Kinase Activity ATP Binding
	Biological Process	Osteoblast Differentiation Endosome Organization Regulation Of Early Endosome To Recycling Endosome Transport Regulation Of Early Endosome To Late Endosome Transport	Protein Phosphorylation DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Signal Transduction Synaptic Transmission Axon Guidance Central Nervous System Development Negative Regulation Of Embryonic Development Negative Regulation Of ERK1 And ERK2 Cascade Negative Regulation Of Mesoderm Development
Pathways			Axon guidance RSK activation Activation of NMDA receptor upon glutamate binding and postsynaptic events L1CAM interactions Recycling pathway of L1 CREB phosphorylation through the activation of Ras Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Transmission across Chemical Synapses Post NMDA receptor activation events
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: CALM1 DNAJB11 GADD45A GSK3B RPS6KA6	28 interactors: ADIRF APP C14orf1 CEBPZ CENPB CLEC3B DHX34 DNAJC13 DNMT1 FBN3 FZD5 LMO4 MAPK3 MASP1 MED24 MICAL1 MPP1 NR4A1 RBPJ RPLP1 RXRA SAP30BP SPTBN4 SYNE4 UBE2I UFM1 ZNF227 ZNF746
Entrez ID		23317	27330
HPRD ID		10915	02250
Ensembl ID		ENSG00000138246
Uniprot IDs		O75165	Q9UK32
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Phosphorylation Regulation Of Phosphorylation Regulation Of Phosphorus Metabolic Process Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Phosphorylation Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Regulation Of Protein Phosphorylation Negative Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Protein Metabolic Process Glycogen Metabolic Process Response To Stress Positive Regulation Of Protein Kinase Activity Cellular Response To Stress Positive Regulation Of Catalytic Activity Positive Regulation Of Kinase Activity Cellular Response To Mechanical Stimulus Polysaccharide Metabolic Process Positive Regulation Of Transferase Activity Signal Transduction In Response To DNA Damage Response To External Stimulus Regulation Of MAPK Cascade Intracellular Signal Transduction ER-nucleus Signaling Pathway Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Cellular Metabolic Process Energy Reserve Metabolic Process Cellular Response To Radiation Regulation Of Protein Metabolic Process Negative Regulation Of Cellular Protein Metabolic Process Negative Regulation Of Type B Pancreatic Cell Development Superior Temporal Gyrus Development Negative Regulation Of MAPK Cascade Response To Endoplasmic Reticulum Stress Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Regulation Of Catalytic Activity Negative Regulation Of Protein Metabolic Process Signal Transduction Re-entry Into Mitotic Cell Cycle Negative Regulation Of Neuron Maturation Cellular Response To Fibroblast Growth Factor Stimulus Positive Regulation Of Cellular Metabolic Process Response To Fibroblast Growth Factor Central Nervous System Development Positive Regulation Of Hydrolase Activity	Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process RNA Biosynthetic Process Positive Regulation Of Cellular Biosynthetic Process Gene Expression Regulation Of Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Transcription, DNA-templated Positive Regulation Of Metabolic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Initiation Positive Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Intracellular Receptor Signaling Pathway Regulation Of Protein Metabolic Process Regulation Of Protein Processing Regulation Of Early Endosome To Late Endosome Transport Cell Differentiation Biosynthetic Process Cardiac Ventricle Development Negative Regulation Of Cellular Metabolic Process Labyrinthine Layer Blood Vessel Development Sterol Metabolic Process Tissue Development Cardiac Chamber Development Neuron Maturation Regulation Of Cell Fate Commitment Apoptotic Process Cell Maturation Negative Regulation Of Protein Processing Regulation Of Cellular Process Tissue Morphogenesis Programmed Cell Death Placenta Blood Vessel Development
Tagcloud ?		1858g 2564a advance causing clathrin d620n descent doi ejhg endosomal et exome genetics haplotype harboring homolog hsp40 journal microsatellite n855s owing publication rs188286943 rs387907571 subfamily taqman tremor vacuolar vps35	anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized
Tagcloud (Difference) ?		1858g 2564a advance causing clathrin d620n descent doi ejhg endosomal et exome genetics haplotype harboring homolog hsp40 journal microsatellite n855s owing publication rs188286943 rs387907571 subfamily taqman tremor vacuolar vps35	anchorage anticipated attribution azacytidine cdna chemoresponse clines codons deleted demethylation depended duplet encompass exclude exon immunoblots indolocarbazole isoforms nt nucleotides penultimate rsk4 situation sparse splice starvation suppressive triplet uncharacterized
Tagcloud (Intersection) ?