SATB2 and FOXP4

Number of citations: 0 (PubMedID 29365100)
Data Source: BioGRID (fluorescent resonance energy transfer)

		SATB2	FOXP4
Name		SATB homeobox 2	forkhead box P4
Structure
GO Annotations	Cellular Component	Histone Deacetylase Complex Chromatin Nucleus Nucleoplasm Transcription Regulator Complex Nuclear Matrix Nuclear Lumen	Chromatin Nucleus Nucleoplasm Cytosol
	Molecular Function	RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Protein Binding Histone Deacetylase Binding Sequence-specific DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Zinc Ion Binding Sequence-specific DNA Binding Metal Ion Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Neuron Migration Osteoblast Development Chromatin Organization Chromatin Remodeling Regulation Of Transcription By RNA Polymerase II Embryonic Pattern Specification Regulation Of Gene Expression Positive Regulation Of Transcription By RNA Polymerase II Embryonic Skeletal System Morphogenesis Cartilage Development Roof Of Mouth Development	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II
Pathways		SUMOylation of chromatin organization proteins RUNX2 regulates osteoblast differentiation	None
GWAS		Appendicular lean mass ( 33097823 ) Autism spectrum disorder or schizophrenia ( 28540026 ) Barrett's esophagus or Esophageal adenocarcinoma ( 27527254 ) Brain cytoarchitecture ( 20308991 ) Cerebrospinal fluid immune biomarker levels ( 32066700 ) Chin dimples ( 27182965 ) Colorectal cancer or advanced adenoma ( 30510241 ) Cortical volume ( 32963231 ) FEV1 ( 30804560 ) Heel bone mineral density ( 30598549 ) Height ( 31562340 ) Insomnia ( 23728906 ) Loneliness (multivariate analysis) ( 27629369 ) Lung function (FVC) ( 30804560 ) Menarche (age at onset) ( 25231870 27182965 29773799 ) Rheumatoid arthritis ( 30891314 ) Schizophrenia ( 29483656 30285260 28991256 25056061 ) Serum alkaline phosphatase levels ( 33547301 ) Sun-seeking behavior ( 32920024 ) Type 2 diabetes ( 25760438 ) Ulcerative colitis ( 20228799 ) Waist circumference ( 23966867 )	Chronotype ( 30696823 ) EGFR mutation-positive lung adenocarcinoma ( 27501781 ) Fasting insulin ( 34059833 ) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223 ) High light scatter reticulocyte count ( 32888494 ) High light scatter reticulocyte percentage of red cells ( 32888494 ) Metabolite levels ( 23823483 ) Non-small cell lung cancer ( 31326317 ) Prostate cancer ( 20676098 31562322 )
Novel Interactors		2 novel interactors: ABI2 ADAM23	None recorded
Interacting Genes		8 interacting genes: FOXP1 FOXP2 FOXP4 HDAC1 MTA2 PIAS1 POLR2J3 RAB3IL1	10 interacting genes: FOXP1 FOXP2 NR2F1 NR2F2 SATB1 SATB2 SOX5 XAGE2 YY1 ZMYM2
Entrez ID		23314	116113
HPRD ID		12178	10600
Ensembl ID		ENSG00000119042	ENSG00000137166
Uniprot IDs		B3KPQ9 Q59FT3 Q9UPW6	B7ZBM3 Q8IVH2
PDB IDs		1WI3 1WIZ 2CSF	6XAT
GO Terms Enriched among Interactors		Negative Regulation Of Transcription By RNA Polymerase II Chromatin Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Androgen Receptor Signaling Pathway NuRD Complex DNA Binding Core Promoter Sequence-specific DNA Binding Negative Regulation Of RNA Biosynthetic Process Histone Deacetylase Activity Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Fate Specification Regulation Of Muscle Cell Differentiation Sequence-specific DNA Binding DNA-binding Transcription Factor Binding Regulation Of Androgen Receptor Signaling Pathway Transcription Corepressor Activity Negative Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Nucleosomal DNA Binding Histone Deacetylase Complex Regulation Of Cell Fate Commitment DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific Negative Regulation Of Macromolecule Biosynthetic Process Putamen Development Caudate Nucleus Development Negative Regulation Of Biosynthetic Process Negative Regulation Of Muscle Cell Differentiation Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Stem Cell Differentiation Positive Regulation Of Smooth Muscle Cell Proliferation Krueppel-associated Box Domain Binding Regulation Of Transcription By RNA Polymerase II Zonula Adherens Assembly Positive Regulation Of Interleukin-21 Production Regulation Of Striated Muscle Cell Differentiation Negative Regulation Of Macromolecule Metabolic Process Protein Lysine Delactylase Activity RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Fungiform Papilla Formation Negative Regulation Of Metabolic Process Protein Decrotonylase Activity Histone Decrotonylase Activity Transcription Coregulator Activity Histone Deacetylase Binding Hair Follicle Placode Formation Zinc Ion Binding Positive Regulation Of Hydrogen Peroxide-mediated Programmed Cell Death Epithelial Cell Proliferation Involved In Lung Morphogenesis Regulation Of Smooth Muscle Cell Proliferation	DNA-binding Transcription Factor Activity Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process DNA Binding Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Macromolecule Metabolic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin Negative Regulation Of Metabolic Process Negative Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Nuclear Matrix Regulation Of Cell Growth Involved In Cardiac Muscle Cell Development Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Negative Regulation Of Cardiac Muscle Tissue Growth Negative Regulation Of Organ Growth Nuclear Lumen Negative Regulation Of Cardiac Muscle Hypertrophy Regulation Of Macromolecule Metabolic Process Negative Regulation Of Muscle Hypertrophy Negative Regulation Of Striated Muscle Cell Differentiation Cellular Developmental Process Zinc Ion Binding Nuclear Receptor Activity Regulation Of Metabolic Process Radial Pattern Formation Putamen Development Caudate Nucleus Development Animal Organ Development Skeletal Muscle Tissue Development Regulation Of Heart Growth Negative Regulation Of Muscle Cell Differentiation Regulation Of Cardiac Muscle Hypertrophy Forebrain Development Cell Differentiation Nucleus Cis-regulatory Region Sequence-specific DNA Binding