SATB2 and MTA2

Number of citations of the paper that reports this interaction (PMID 18333962)
18

Data Source:
BioGRID (pull down)

		SATB2	MTA2
Gene Name		SATB homeobox 2	metastasis associated 1 family, member 2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Histone Deacetylase Complex Nucleoplasm Transcription Factor Complex Cytoplasm Nuclear Matrix	Histone Deacetylase Complex Nuclear Chromatin Nucleoplasm Transcription Factor Complex Membrane NuRD Complex Protein Complex
	Molecular Function	Chromatin Binding Protein Binding Sequence-specific DNA Binding	RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding RNA Polymerase II Distal Enhancer Sequence-specific DNA Binding Transcription Factor Binding Transcription Factor Activity RNA Polymerase II Transcription Factor Binding RNA Polymerase II Repressing Transcription Factor Binding Sequence-specific DNA Binding Transcription Factor Activity Histone Deacetylase Activity Protein Binding Zinc Ion Binding Nucleosomal DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Neuron Migration Osteoblast Development Chromatin Remodeling Transcription, DNA-templated Embryonic Pattern Specification Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Morphogenesis Cartilage Development Palate Development Cellular Response To Organic Substance	Negative Regulation Of Transcription From RNA Polymerase II Promoter DNA Methylation Chromatin Organization Chromatin Assembly Or Disassembly Histone Deacetylation ATP-dependent Chromatin Remodeling Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways			Chromatin modifying enzymes Chromatin organization HDACs deacetylate histones RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance
Drugs
Diseases
GWAS		Brain cytoarchitecture ( 20308991) Insomnia ( 23728906) Ulcerative colitis ( 20228799)
Protein-Protein Interactions		4 interactors: HDAC1 MTA2 PIAS1 RAB3IL1	21 interactors: APPL1 APPL2 BCL11B ESR1 FKBP3 HDAC2 HIST3H3 HNRNPD MBD3 MBD3L2 MED30 NACC2 RBBP4 RBBP7 SATB1 SATB2 SPEN TP53 TSC22D3 UBE3C YY1
Entrez ID		23314	9219
HPRD ID		12178	07233
Ensembl ID		ENSG00000119042	ENSG00000149480
Uniprot IDs		B3KPQ9 Q59FT3 Q9UPW6	O94776
PDB IDs		1WI3 1WIZ 2CSF
Enriched GO Terms of Interacting Partners?		Histone Deacetylation Protein Deacetylation ATP-dependent Chromatin Remodeling Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Remodeling Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Smooth Muscle Cell Differentiation Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Histone Modification Positive Regulation Of Receptor Biosynthetic Process Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation By Host Of Viral Transcription Fungiform Papilla Formation Negative Regulation Of Androgen Receptor Signaling Pathway Positive Regulation Of Protein Sumoylation Fungiform Papilla Morphogenesis Negative Regulation Of Cellular Metabolic Process Fungiform Papilla Development Regulation Of Receptor Biosynthetic Process Regulation Of Smooth Muscle Cell Differentiation Eyelid Development In Camera-type Eye Hair Follicle Placode Formation Regulation Of Protein Sumoylation Regulation Of Androgen Receptor Signaling Pathway Tongue Morphogenesis Regulation Of Interferon-gamma-mediated Signaling Pathway Negative Regulation Of Viral Transcription Chromatin Modification Regulation Of Response To Interferon-gamma Histone H4 Deacetylation Protein Sumoylation Positive Regulation Of Cellular Metabolic Process Chromatin Organization Interaction With Symbiont Histone H3 Deacetylation Regulation Of Signal Transduction Negative Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Histone H3-K9 Modification Tongue Development Androgen Receptor Signaling Pathway Regulation Of Signaling	Negative Regulation Of Gene Expression Chromosome Organization Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter RNA Biosynthetic Process Chromatin Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process RNA Metabolic Process Chromatin Modification Regulation Of Nitrogen Compound Metabolic Process Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Negative Regulation Of Cellular Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Transcription From RNA Polymerase II Promoter ATP-dependent Chromatin Remodeling Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Gene Expression, Epigenetic Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Organelle Organization Positive Regulation Of Macromolecule Biosynthetic Process Cell Proliferation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Gene Expression, Epigenetic Commitment Of Neuronal Cell To Specific Neuron Type In Forebrain Rhythmic Process Regulation Of Apoptotic Process Forebrain Neuron Fate Commitment Cellular Metabolic Process Regulation Of Cell Death DNA Metabolic Process Negative Regulation Of Cell Proliferation Chromatin Assembly
Tagcloud ?		anomalies cleft clefts cnv cnvs comprise disrupting doi etiology fgf8 foxe1 gli2 grouped highlighting irf6 jhg journal kif7 lip mentioned msx1 msx2 ofc ofcs orofacial palate postulated ski tceb3	ag ag1478 blocking combat combinatorial dosage egfr exerts fasn greatly hsp90 ideal iialpha iressa isotope labeling lc mechanistically oncogenes phosphatidylinositol pi3k pi4kiialpha prdx2 presents proteomic silac strengthened ultimately xenograft
Tagcloud (Difference) ?		anomalies cleft clefts cnv cnvs comprise disrupting doi etiology fgf8 foxe1 gli2 grouped highlighting irf6 jhg journal kif7 lip mentioned msx1 msx2 ofc ofcs orofacial palate postulated ski tceb3	ag ag1478 blocking combat combinatorial dosage egfr exerts fasn greatly hsp90 ideal iialpha iressa isotope labeling lc mechanistically oncogenes phosphatidylinositol pi3k pi4kiialpha prdx2 presents proteomic silac strengthened ultimately xenograft
Tagcloud (Intersection) ?