DIP2A and DLX2

Number of citations of the paper that reports this interaction (PMID 11675124)
7

Data Source:
HPRD (two hybrid)

		DIP2A	DLX2
Gene Name		DIP2 disco-interacting protein 2 homolog A (Drosophila)	distal-less homeobox 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cell Surface	Nucleus
	Molecular Function	Catalytic Activity Protein Binding Transcription Factor Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Single-stranded RNA Binding Sequence-specific DNA Binding
	Biological Process	Multicellular Organismal Development Metabolic Process Negative Regulation Of Gene Expression Regulation Of Apoptotic Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Brain Development Proximal/distal Pattern Formation Subpallium Development Hippocampus Development Olfactory Bulb Development Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Cerebral Cortex GABAergic Interneuron Fate Commitment Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Cranial Skeleton Morphogenesis Negative Regulation Of Oligodendrocyte Differentiation Branching Morphogenesis Of A Nerve Cartilage Development
Pathways
Drugs
Diseases
GWAS			Breast cancer ( 23535729)
Protein-Protein Interactions		18 interactors: ADAMTSL4 AES CCDC33 CEP44 DAB2 DLX2 FAM214B GPATCH2L JMJD6 MBIP PSME3 PTPN3 SORBS3 STAC3 TMCC2 TRIM39 TRIP13 ZBTB43	14 interactors: AVP BZRAP1 DGCR6 DIP2A DLX5 GRN HOXC8 MSX1 MSX2 MVP NCOA2 PARK2 PIK3R1 XRCC6
Entrez ID		23181	1746
HPRD ID		07611	00527
Ensembl ID		ENSG00000160305	ENSG00000115844
Uniprot IDs		Q14689 Q96NX2	Q07687 Q53QU7
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of Cellular Metabolic Process Regulation Of Protein Catabolic Process Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Metabolic Process Regulation Of Cellular Process Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Signal Transduction Regulation Of Canonical Wnt Signaling Pathway Regulation Of Signal Transduction Negative Regulation Of Signaling Regulation Of Proteolysis Negative Regulation Of Protein Binding Regulation Of Signaling Regulation Of Wnt Signaling Pathway Inactivation Of MAPK Activity Involved In Osmosensory Signaling Pathway Histone H3-R2 Demethylation Histone H4-R3 Demethylation Peptidyl-lysine Hydroxylation To 5-hydroxy-L-lysine Regulation Of Apoptotic Process Negative Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Death Negative Regulation Of Protein Metabolic Process Leading Edge Cell Differentiation Regulation Of Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Binding Negative Regulation Of Protein Ubiquitination Apoptotic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Clathrin-mediated Endocytosis Programmed Cell Death Negative Regulation Of Protein Catabolic Process Cell Death Death Cerebral Cortex GABAergic Interneuron Fate Commitment Liver Regeneration Positive Regulation Of Anoikis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Membrane Depolarization During Action Potential Positive Regulation Of Early Endosome To Late Endosome Transport Branching Morphogenesis Of A Nerve Regulation Of Cellular Protein Metabolic Process Positive Regulation Of Proteolysis Involved In Cellular Protein Catabolic Process Regulation Of Protein Binding Organ Development Positive Regulation Of Cellular Protein Catabolic Process Positive Regulation Of Wnt Signaling Pathway Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment	Positive Regulation Of Mesenchymal Cell Apoptotic Process Embryonic Nail Plate Morphogenesis Activation Of Meiosis Regulation Of Transcription From RNA Polymerase II Promoter BMP Signaling Pathway Involved In Heart Development Negative Regulation Of Cellular Metabolic Process Nail Development Positive Regulation Of Gene Expression BMP Signaling Pathway Hyperosmotic Salinity Response Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Morphogenesis Regulation Of DNA Binding Protein Stabilization Negative Regulation Of Transcription Regulatory Region DNA Binding Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Multicellular Organismal Development Bone Morphogenesis Positive Regulation Of Meiotic Nuclear Division Negative Regulation Of Release Of Cytochrome C From Mitochondria Endocardial Cushion Formation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Stability Hyperosmotic Response Endocardial Cushion Morphogenesis Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Apoptotic Process Embryonic Limb Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signaling Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Death Transcription, DNA-templated Limb Morphogenesis Developmental Process Negative Regulation Of Cell Death Negative Regulation Of Mitochondrion Organization RNA Biosynthetic Process Organ Morphogenesis Signal Transduction Involved In Regulation Of Gene Expression Signaling Limb Development Face Morphogenesis
Tagcloud ?			acquiring adopt ascl1 assemble bhlh combinatorial derepression derivative diencephalic discrete dlx5 dlxs helt interneurons nuclei prethalamic prethalamus progenitor relaying rostral spatiotemporal specification specified surprisingly th thalamic thalamus tracing whereby
Tagcloud (Difference) ?			acquiring adopt ascl1 assemble bhlh combinatorial derepression derivative diencephalic discrete dlx5 dlxs helt interneurons nuclei prethalamic prethalamus progenitor relaying rostral spatiotemporal specification specified surprisingly th thalamic thalamus tracing whereby
Tagcloud (Intersection) ?