DLX2 and DIP2A

Number of citations of the paper that reports this interaction (PubMedID 11675124)
0

Data Source:
HPRD (two hybrid)

		DLX2	DIP2A
Description		distal-less homeobox 2	disco interacting protein 2 homolog A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus	Mitochondrion Plasma Membrane Cell Surface Membrane Cell Projection Dendritic Spine Synapse
	Molecular Function	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Chromatin Binding DNA-binding Transcription Factor Activity Single-stranded RNA Binding Protein Binding Sequence-specific Double-stranded DNA Binding	Acetate-CoA Ligase Activity Protein Binding Ligase Activity
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of DNA-templated Transcription Regulation Of Transcription By RNA Polymerase II Notch Signaling Pathway Brain Development Proximal/distal Pattern Formation Neuroblast Differentiation Subpallium Development Hippocampus Development Olfactory Bulb Development Forebrain Neuron Differentiation Cerebral Cortex GABAergic Interneuron Differentiation Cerebral Cortex GABAergic Interneuron Fate Commitment Cell Differentiation Odontogenesis Of Dentin-containing Tooth Positive Regulation Of Cell Differentiation Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Photoreceptor Cell Differentiation Embryonic Cranial Skeleton Morphogenesis Embryonic Skeletal System Development Oligodendrocyte Differentiation Negative Regulation Of Oligodendrocyte Differentiation Branching Morphogenesis Of A Nerve Cartilage Development GABAergic Neuron Differentiation Positive Regulation Of Amacrine Cell Differentiation	Acetyl-CoA Biosynthetic Process Nervous System Development Negative Regulation Of Gene Expression Dendritic Spine Morphogenesis Positive Regulation Of Peptidyl-lysine Acetylation
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729) Food allergy ( 29030101) Peanut allergy ( 29030101)	Anti-saccade response ( 29064472) Lymphocyte count ( 27863252 32888494) Mean corpuscular volume ( 32888494) Mean reticulocyte volume ( 32888494) Mean spheric corpuscular volume ( 32888494) Neutrophil count ( 32888494) Pulse pressure ( 30224653) White blood cell count ( 32888494)
Interacting Genes		14 interacting genes: AVP DGCR6 DIP2A DLX5 GRN HOXC8 MSX1 MSX2 MVP NCOA2 PIK3R1 PRKN TSPOAP1 XRCC6	20 interacting genes: ADAMTSL4 ATOSB CCDC33 CEP44 DAB2 DLX2 DSCAM GPATCH2L IQUB JMJD6 MBIP PSME3 PTPN3 SORBS3 STAC3 TLE5 TMCC2 TRIM39 TRIP13 ZBTB43
Entrez ID		1746	23181
HPRD ID		00527	07611
Ensembl ID		ENSG00000115844	ENSG00000160305
Uniprot IDs		Q07687 Q53QU7 X5D7D8	A0A494C143 Q14689 Q96NX2
PDB IDs
Enriched GO Terms of Interacting Partners?		Bone Morphogenesis Embryonic Nail Plate Morphogenesis Cell Surface Receptor Signaling Pathway Involved In Heart Development Activation Of Meiosis Positive Regulation Of Mesenchymal Cell Apoptotic Process Locomotory Behavior Regulation Of Primary Metabolic Process Negative Regulation Of Programmed Cell Death Regulation Of Macromolecule Metabolic Process Negative Regulation Of Apoptotic Process Transcription Cis-regulatory Region Binding Embryonic Limb Morphogenesis Animal Organ Morphogenesis BMP Signaling Pathway Transcription Regulator Complex Protein Stabilization Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Mammary Gland Epithelium Development Mesenchymal Cell Apoptotic Process Negative Regulation Of Metabolic Process Positive Regulation Of Meiotic Nuclear Division Cardiac Conduction System Development Limb Morphogenesis Response To Salt Stress Cellular Homeostasis Enzyme-linked Receptor Protein Signaling Pathway Regulation Of Metabolic Process Regulation Of Cell Population Proliferation Positive Regulation Of Multicellular Organismal Process Positive Regulation Of Macromolecule Metabolic Process Regulation Of Protein Stability Positive Regulation Of Meiotic Cell Cycle Regulation Of Transcription By RNA Polymerase II Embryonic Hindlimb Morphogenesis Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Transcription By RNA Polymerase II Face Morphogenesis Anterior/posterior Pattern Specification Embryonic Forelimb Morphogenesis Negative Regulation Of DNA-templated Transcription Negative Regulation Of Macromolecule Metabolic Process Regulation Of Meiotic Nuclear Division Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Regulation Of Cell Communication Transforming Growth Factor Beta Receptor Superfamily Signaling Pathway Positive Regulation Of Developmental Process Hindlimb Morphogenesis Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Negative Regulation Of Actin Filament Bundle Assembly
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