DLX2

Gene Name		distal-less homeobox 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus
	Molecular Function	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Single-stranded RNA Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Brain Development Proximal/distal Pattern Formation Subpallium Development Hippocampus Development Olfactory Bulb Development Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Cerebral Cortex GABAergic Interneuron Fate Commitment Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Cranial Skeleton Morphogenesis Negative Regulation Of Oligodendrocyte Differentiation Branching Morphogenesis Of A Nerve Cartilage Development
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729)
Protein-protein Interactions		14 interactors: AVP BZRAP1 DGCR6 DIP2A DLX5 GRN HOXC8 MSX1 MSX2 MVP NCOA2 PARK2 PIK3R1 XRCC6
Entrez ID		1746
HPRD ID		00527
Ensembl ID		ENSG00000115844
Uniprot IDs		Q07687 Q53QU7
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mesenchymal Cell Apoptotic Process Embryonic Nail Plate Morphogenesis Activation Of Meiosis Regulation Of Transcription From RNA Polymerase II Promoter BMP Signaling Pathway Involved In Heart Development Negative Regulation Of Cellular Metabolic Process Nail Development Positive Regulation Of Gene Expression BMP Signaling Pathway Hyperosmotic Salinity Response Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Morphogenesis Regulation Of DNA Binding Protein Stabilization Negative Regulation Of Transcription Regulatory Region DNA Binding Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Multicellular Organismal Development Bone Morphogenesis Positive Regulation Of Meiotic Nuclear Division Negative Regulation Of Release Of Cytochrome C From Mitochondria Endocardial Cushion Formation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Stability Hyperosmotic Response Endocardial Cushion Morphogenesis Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Apoptotic Process Embryonic Limb Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signaling Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Death Transcription, DNA-templated Limb Morphogenesis Developmental Process Negative Regulation Of Cell Death Negative Regulation Of Mitochondrion Organization RNA Biosynthetic Process Organ Morphogenesis Signal Transduction Involved In Regulation Of Gene Expression Signaling Limb Development Face Morphogenesis
Tagcloud ?		acquiring adopt ascl1 assemble bhlh combinatorial derepression derivative diencephalic discrete dlx5 dlxs helt interneurons nuclei prethalamic prethalamus progenitor relaying rostral spatiotemporal specification specified surprisingly th thalamic thalamus tracing whereby