DLX2 and MVP

Number of citations of the paper that reports this interaction (PMID 24722188)
1

Data Source:
BioGRID (two hybrid)

		DLX2	MVP
Gene Name		distal-less homeobox 2	major vault protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nuclear Pore Cytoplasm Cytoskeleton Membrane Ribonucleoprotein Complex Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Single-stranded RNA Binding Sequence-specific DNA Binding	Protein Binding Protein Kinase Binding Protein Phosphatase Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Brain Development Proximal/distal Pattern Formation Subpallium Development Hippocampus Development Olfactory Bulb Development Regulation Of Transcription From RNA Polymerase II Promoter Involved In Forebrain Neuron Fate Commitment Cerebral Cortex GABAergic Interneuron Fate Commitment Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Notch Signaling Pathway Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Cranial Skeleton Morphogenesis Negative Regulation Of Oligodendrocyte Differentiation Branching Morphogenesis Of A Nerve Cartilage Development	Cell Proliferation Protein Transport Negative Regulation Of Signaling Negative Regulation Of Protein Autophosphorylation ERBB Signaling Pathway MRNA Transport Negative Regulation Of Protein Tyrosine Kinase Activity Protein Activation Cascade
Pathways
Drugs
Diseases
GWAS		Breast cancer ( 23535729)
Protein-Protein Interactions		14 interactors: AVP BZRAP1 DGCR6 DIP2A DLX5 GRN HOXC8 MSX1 MSX2 MVP NCOA2 PARK2 PIK3R1 XRCC6	57 interactors: ADAMTSL4 AES BANP BZRAP1 C1orf94 CALCOCO2 CAMK2B CCDC36 CKAP4 CYTB DISC1 DLX2 EPHX2 ESR1 FAM154A FAM46C GIT2 GOLGA2 HP KCTD9 KPNA2 KPNA3 MDFI MEOX1 MEOX2 MID2 MKL1 NNT NOTCH2NL OBFC1 PARP4 PIH1D2 PLSCR1 POT1 PSTPIP1 PTEN PTPN11 RAB3IP RBPMS REL RHOXF2 RIMBP3 RNF111 SERTAD1 SKIL SLC2A4 TCF4 TFCP2 TP53 TRAF2 TRIM27 TRIM42 TRIP13 TRIP6 VAC14 ZBTB32 ZMIZ2
Entrez ID		1746	9961
HPRD ID		00527	05475
Ensembl ID		ENSG00000115844	ENSG00000013364
Uniprot IDs		Q07687 Q53QU7	B4DP93 Q14764
PDB IDs			1Y7X
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Mesenchymal Cell Apoptotic Process Embryonic Nail Plate Morphogenesis Activation Of Meiosis Regulation Of Transcription From RNA Polymerase II Promoter BMP Signaling Pathway Involved In Heart Development Negative Regulation Of Cellular Metabolic Process Nail Development Positive Regulation Of Gene Expression BMP Signaling Pathway Hyperosmotic Salinity Response Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Skeletal System Morphogenesis Regulation Of DNA Binding Protein Stabilization Negative Regulation Of Transcription Regulatory Region DNA Binding Epithelial To Mesenchymal Transition Involved In Endocardial Cushion Formation Multicellular Organismal Development Bone Morphogenesis Positive Regulation Of Meiotic Nuclear Division Negative Regulation Of Release Of Cytochrome C From Mitochondria Endocardial Cushion Formation Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of Protein Stability Hyperosmotic Response Endocardial Cushion Morphogenesis Regulation Of Transcription Regulatory Region DNA Binding Regulation Of Apoptotic Process Embryonic Limb Morphogenesis Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signaling Cardiac Epithelial To Mesenchymal Transition Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Cell Death Transcription, DNA-templated Limb Morphogenesis Developmental Process Negative Regulation Of Cell Death Negative Regulation Of Mitochondrion Organization RNA Biosynthetic Process Organ Morphogenesis Signal Transduction Involved In Regulation Of Gene Expression Signaling Limb Development Face Morphogenesis	Regulation Of Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Signal Transduction Regulation Of Signal Transduction Regulation Of Nucleic Acid-templated Transcription Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Signaling Cellular Aromatic Compound Metabolic Process Biosynthetic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Regulation Of Cellular Process Positive Regulation Of Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Response To Cytokine RNA Metabolic Process Defense Response Positive Regulation Of Cellular Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Gene Expression Response To Stress Positive Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Immune System Process Nitrogen Compound Metabolic Process Negative Regulation Of Signaling Negative Regulation Of Transcription From RNA Polymerase II Promoter Response To Organic Substance Positive Regulation Of Apoptotic Process Protein Localization To Nucleus Positive Regulation Of Programmed Cell Death Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Regulation Of Intracellular Signal Transduction Cellular Metabolic Process Regulation Of Cell Death Negative Regulation Of Cellular Metabolic Process Regulation Of Catalytic Activity
Tagcloud ?		acquiring adopt ascl1 assemble bhlh combinatorial derepression derivative diencephalic discrete dlx5 dlxs helt interneurons nuclei prethalamic prethalamus progenitor relaying rostral spatiotemporal specification specified surprisingly th thalamic thalamus tracing whereby	afp bleomycin bronchogenic cap chance cisplatin cooperative crs cyclophosphamide doxorubicin eastern ecog efficacious entered est evaluable fluorouracil institution lethal mitomycin modest nscbc october oncology prs regimens shrinkage threatening vinblastine
Tagcloud (Difference) ?		acquiring adopt ascl1 assemble bhlh combinatorial derepression derivative diencephalic discrete dlx5 dlxs helt interneurons nuclei prethalamic prethalamus progenitor relaying rostral spatiotemporal specification specified surprisingly th thalamic thalamus tracing whereby	afp bleomycin bronchogenic cap chance cisplatin cooperative crs cyclophosphamide doxorubicin eastern ecog efficacious entered est evaluable fluorouracil institution lethal mitomycin modest nscbc october oncology prs regimens shrinkage threatening vinblastine
Tagcloud (Intersection) ?