CIC and GABPB1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CIC	GABPB1
Gene Name		capicua transcriptional repressor	GA binding protein transcription factor, beta subunit 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	DNA Binding Chromatin Binding Protein Binding	Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Lung Alveolus Development	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Organelle Organization Mitochondrion Organization Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ATXN1 CENPJ CSNK2B GABPB1 GTPBP3 NFYC PICK1 PLK1 PYCR2 SEC62 SETD2 TRIM22 ZNRD1	23 interactors: ATF1 BAI2 CIC FAM90A1 FANCG GABPA HCFC1 IL16 LMO1 LMO3 LMO4 MAGEB18 POGZ RBM11 RSPH14 RYBP SNRPA SNRPB2 TDRD7 TRAF2 USO1 YAF2 ZDHHC17
Entrez ID		23152	2553
HPRD ID		10831	15975
Ensembl ID		ENSG00000079432	ENSG00000104064
Uniprot IDs		Q96RK0	Q06547
PDB IDs		4J2J 4J2L
Enriched GO Terms of Interacting Partners?		Heterocycle Metabolic Process Nitrogen Compound Metabolic Process Histone H3-K36 Trimethylation RNA Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Nucleobase-containing Compound Metabolic Process DNA-templated Transcription, Elongation Activation Of APC-Cdc20 Complex Activity Cellular Aromatic Compound Metabolic Process Centrosome Organization Positive Regulation Of Cellular Metabolic Process Regulation Of Gene Expression Cell Migration Involved In Vasculogenesis Microtubule Organizing Center Organization Cellular Nitrogen Compound Metabolic Process G2/M Transition Of Mitotic Cell Cycle Polar Body Extrusion After Meiotic Divisions Cellular Metabolic Process Activation Of Anaphase-promoting Complex Activity Meiotic Cytokinesis L-proline Biosynthetic Process Posttranslational Protein Targeting To Membrane Positive Regulation Of Mitotic Metaphase/anaphase Transition Positive Regulation Of Activin Receptor Signaling Pathway DNA Methylation Involved In Embryo Development Adiponectin-activated Signaling Pathway Regulation Of MRNA Export From Nucleus Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Metaphase/anaphase Transition Of Mitotic Cell Cycle Histone H3-K36 Methylation Dendritic Spine Maintenance Regulation Of Metabolic Process Regulation Of Gene Expression, Epigenetic Positive Regulation Of Metabolic Process Tube Development Coronary Vasculature Morphogenesis Endothelial Tube Morphogenesis Gene Expression Regulation Of Centriole Replication Protein Localization To Chromatin Neuronal Ion Channel Clustering Mitotic Cell Cycle Regulation Of RNA Export From Nucleus Negative Regulation Of Arp2/3 Complex-mediated Actin Nucleation	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Cellular Nitrogen Compound Metabolic Process Transcription, DNA-templated Regulation Of RNA Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Glucocorticoid Receptor Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Cellular Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Transcription From RNA Polymerase II Promoter TRIF-dependent Toll-like Receptor Signaling Pathway Positive Regulation Of Cellular Biosynthetic Process MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway Release From Viral Latency Golgi Vesicle Docking Regulation Of Metabolic Process Toll-like Receptor 4 Signaling Pathway Biosynthetic Process Cellular Protein Complex Assembly RNA Splicing Cellular Metabolic Process Positive Regulation Of Cellular Metabolic Process Toll-like Receptor Signaling Pathway Mitochondrion Organization Negative Regulation Of Megakaryocyte Differentiation MRNA Processing Transcription From RNA Polymerase II Promoter Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction
Tagcloud ?		aetiology assumed bacteriuria catheterization clean complaints distress epq evaluations eysenck ghq intermittent inventory neurogenic neurotic neuroticism personality practised prescription psychometric spielberger stai thirds tolerability trait undergone unnecessary verify x1	arsenic as1 cadmium capabilities cdkn2b chemical coding cycloheximide ethical flj33630 hipscs ideal indicators linc00152 linc0541471 lncrnas mir22hg mrnas peroxide pervasive pluripotent possess renewal responded rnas stresses surrogate toxicological v2
Tagcloud (Difference) ?		aetiology assumed bacteriuria catheterization clean complaints distress epq evaluations eysenck ghq intermittent inventory neurogenic neurotic neuroticism personality practised prescription psychometric spielberger stai thirds tolerability trait undergone unnecessary verify x1	arsenic as1 cadmium capabilities cdkn2b chemical coding cycloheximide ethical flj33630 hipscs ideal indicators linc00152 linc0541471 lncrnas mir22hg mrnas peroxide pervasive pluripotent possess renewal responded rnas stresses surrogate toxicological v2
Tagcloud (Intersection) ?