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DCUN1D4 and CUL2
Number of citations of the paper that reports this interaction (PMID
23201271
)
5
Data Source:
BioGRID
(pull down)
DCUN1D4
CUL2
Gene Name
DCN1, defective in cullin neddylation 1, domain containing 4
cullin 2
Image
No pdb structure
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Nucleoplasm
Cytosol
Cul2-RING Ubiquitin Ligase Complex
Molecular Function
Molecular_function
Protein Binding
Protein Binding
Ubiquitin Protein Ligase Binding
Biological Process
Biological_process
G1/S Transition Of Mitotic Cell Cycle
Ubiquitin-dependent Protein Catabolic Process
Cell Cycle Arrest
Negative Regulation Of Cell Proliferation
Viral Process
Protein Ubiquitination
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Cellular Response To Hypoxia
Intrinsic Apoptotic Signaling Pathway
Pathways
Cellular response to hypoxia
Antigen processing: Ubiquitination & Proteasome degradation
Regulation of Hypoxia-inducible Factor (HIF) by oxygen
Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha
Class I MHC mediated antigen processing & presentation
Adaptive Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions
8 interactors:
CUL1
CUL2
CUL3
CUL4A
CUL4B
CUL5
UBE2M
VAV2
20 interactors:
ARID1B
CAND1
CDC34
COMMD1
COPS5
DCUN1D1
DCUN1D4
GPS1
KAT2A
MKNK2
NEDD8
PRAME
RNF7
SAP130
SENP8
TCEB1
UBE2D1
VHL
ZER1
ZYG11B
Entrez ID
23142
8453
HPRD ID
13791
06786
Ensembl ID
ENSG00000109184
ENSG00000108094
Uniprot IDs
B4DH25
B4DH26
Q92564
Q13617
PDB IDs
Enriched GO Terms of Interacting Partners
?
Protein Ubiquitination
Protein Modification By Small Protein Conjugation
Apoptotic Signaling Pathway
Cell Cycle Arrest
G1/S Transition Of Mitotic Cell Cycle
Intrinsic Apoptotic Signaling Pathway
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Protein Catabolic Process
Mitotic Cell Cycle Phase Transition
Cell Cycle Phase Transition
Cellular Macromolecule Catabolic Process
Regulation Of Cell Cycle
Apoptotic Process
Negative Regulation Of Cell Cycle
Programmed Cell Death
Cell Death
Death
Protein Monoubiquitination
Positive Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Phase Transition
Cell Cycle
Mitotic Cell Cycle Process
Mitotic Cell Cycle
Proteolysis
Catabolic Process
Intracellular Signal Transduction
Cellular Protein Modification Process
Positive Regulation Of Mitotic Cell Cycle
Cell Cycle Process
Viral Process
Positive Regulation Of G1/S Transition Of Mitotic Cell Cycle
Positive Regulation Of Cell Cycle G1/S Phase Transition
Cellular Response To Stimulus
Negative Regulation Of Cell Proliferation
Positive Regulation Of Protein Catabolic Process
Regulation Of Mitotic Cell Cycle Phase Transition
Positive Regulation Of Cell Cycle Process
Regulation Of Cell Proliferation
Cellular Protein Metabolic Process
Regulation Of Cell Cycle Phase Transition
Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process
Proteasomal Protein Catabolic Process
Positive Regulation Of Cell Cycle
Signal Transduction
Response To Stimulus
Regulation Of Protein Catabolic Process
Protein Metabolic Process
Cellular Protein Modification Process
Protein Deneddylation
Cellular Protein Metabolic Process
Protein Modification By Small Protein Conjugation
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Protein Modification By Small Protein Removal
Protein Ubiquitination
Protein Metabolic Process
Regulation Of Transcription From RNA Polymerase II Promoter In Response To Stress
Regulation Of DNA-templated Transcription In Response To Stress
Cullin Deneddylation
Protein Neddylation
Regulation Of Transcription From RNA Polymerase II Promoter
Regulation Of Gene Expression
Cellular Response To Hypoxia
Cellular Response To Decreased Oxygen Levels
Cellular Response To Oxygen Levels
Proteolysis
Regulation Of Transcription, DNA-templated
Regulation Of Nucleic Acid-templated Transcription
Regulation Of RNA Biosynthetic Process
Regulation Of RNA Metabolic Process
Regulation Of Metabolic Process
Cellular Metabolic Process
Positive Regulation Of Transcription, DNA-templated
Regulation Of Nitrogen Compound Metabolic Process
Protein K48-linked Ubiquitination
Positive Regulation Of Cellular Metabolic Process
Regulation Of Protein Ubiquitination
Ubiquitin-dependent Protein Catabolic Process
Modification-dependent Protein Catabolic Process
Histone H3 Acetylation
Positive Regulation Of Macromolecule Biosynthetic Process
Proteolysis Involved In Cellular Protein Catabolic Process
Cellular Protein Catabolic Process
Positive Regulation Of Gene Expression
Positive Regulation Of Cellular Biosynthetic Process
Protein Catabolic Process
Transcription, DNA-templated
Response To Hypoxia
RNA Biosynthetic Process
SCF Complex Assembly
Regulation Of Cellular Process
Regulation Of Ubiquitin-protein Transferase Activity
Positive Regulation Of Metabolic Process
Negative Regulation Of Transcription From RNA Polymerase II Promoter In Response To Hypoxia
Positive Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Exosomal Secretion
Protein Deubiquitination
Histone Acetylation
Tagcloud
?
adrenal
arise
bc
chromaffin
cnl
copy
disrupting
elongin
enrichment
harbored
heterozygosity
hif1
hif1a
hippel
hypoxic
indeed
inherited
lindau
merit
normoxic
pcc
pheochromocytomas
predisposing
pseudohypoxic
rbx1
tceb1
tceb2
vhl
von
Tagcloud (Difference)
?
adrenal
arise
bc
chromaffin
cnl
copy
disrupting
elongin
enrichment
harbored
heterozygosity
hif1
hif1a
hippel
hypoxic
indeed
inherited
lindau
merit
normoxic
pcc
pheochromocytomas
predisposing
pseudohypoxic
rbx1
tceb1
tceb2
vhl
von
Tagcloud (Intersection)
?