POGZ and NFYC

Number of citations of the paper that reports this interaction (PMID 20936779)
48

Data Source:
BioGRID (two hybrid)

		POGZ	NFYC
Gene Name		pogo transposable element with ZNF domain	nuclear transcription factor Y, gamma
Image
Gene Ontology Annotations	Cellular Component	Nuclear Chromatin Nucleus Nucleoplasm Cytoplasm	Nucleus Nucleoplasm CCAAT-binding Factor Complex Protein-DNA Complex
	Molecular Function	DNA Binding Protein Binding Metal Ion Binding	DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Coactivator Activity Protein Binding Transcription Factor Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding Protein Heterodimerization Activity
	Biological Process	Mitotic Sister Chromatid Cohesion Cell Division Kinetochore Assembly	Transcription, DNA-templated Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Protein Folding Cellular Lipid Metabolic Process Small Molecule Metabolic Process Positive Regulation Of Transcription, DNA-templated
Pathways			PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins ATF4 activates genes ATF6-alpha activates chaperone genes Regulation of cholesterol biosynthesis by SREBP (SREBF) Activation of gene expression by SREBF (SREBP) Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha) PERK regulates gene expression ATF6-alpha activates chaperones Unfolded Protein Response (UPR)
Drugs
Diseases
GWAS		Blood trace element (Cu levels) ( 23720494)	Platelet counts ( 21507922)
Protein-Protein Interactions		19 interactors: APP BANP CDK6 CREB1 DAB1 DAZAP2 GABPB1 HGS HIST3H3 NFYA NFYC NRF1 POU2F1 PRR20A RBPMS SP1 VAV2 ZBTB24 ZXDC	27 interactors: ADNP2 ARID2 ATF6 ATF6B CIC CSN2 DR1 DST GAPDH GLTSCR1 GLTSCR1L KIAA2018 LMO4 MYC NFYA NFYB POGZ SMAD2 SMAD3 SNX2 SP1 SREBF2 TAF11 TAF12 TAF6 TBP ZDHHC17
Entrez ID		23126	4802
HPRD ID		11445	05633
Ensembl ID		ENSG00000143442	ENSG00000066136
Uniprot IDs		Q7Z3K3	Q13952
PDB IDs		2E72	1N1J 4AWL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Gene Expression Positive Regulation Of Metabolic Process Regulation Of Gene Expression Positive Regulation Of Cellular Metabolic Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated RNA Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Gene Expression Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Cellular Macromolecule Biosynthetic Process Nitrogen Compound Metabolic Process Macromolecule Biosynthetic Process Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Biosynthetic Process Negative Regulation Of JAK-STAT Cascade Notch Signaling Pathway Regulation Of Cellular Process Hematopoietic Progenitor Cell Differentiation Cell Differentiation Forebrain Development Transcription From RNA Polymerase II Promoter Immune System Process Multicellular Organismal Development Organ Development Cell-cell Adhesion Involved In Neuronal-glial Interactions Involved In Cerebral Cortex Radial Glia Guided Migration Cell Dedifferentiation Sequestering Of Nodal From Receptor Via Nodal Binding Anatomical Structure Morphogenesis Hemopoiesis System Development Cellular Metabolic Process Respiratory System Development Rhythmic Process Immune System Development Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Negative Regulation Of Nodal Signaling Pathway Cerebellum Structural Organization	Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process RNA Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Gene Expression Biosynthetic Process Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Initiation Regulation Of Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Regulation Of Metabolic Process DNA-templated Transcription, Elongation Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter In Response To Endoplasmic Reticulum Stress Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Transforming Growth Factor Beta Receptor Signaling Pathway Negative Regulation Of RNA Biosynthetic Process Primary MiRNA Processing Viral Process Regulation Of Nodal Signaling Pathway Cellular Metabolic Process SMAD Protein Complex Assembly Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Paraxial Mesoderm Morphogenesis Positive Regulation By Host Of Viral Transcription Positive Regulation Of Metabolic Process Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway
Tagcloud ?			associates attempt blastocyst cdc25a cdc42 egg embryonal esg1 exist forced icm immediately immunoprecipitated inner kh notion nr5a2 oct3 overlap pluripotency polar pou5f1 preimplantation supporting te transcript transcriptase transcripts trophectoderm
Tagcloud (Difference) ?			associates attempt blastocyst cdc25a cdc42 egg embryonal esg1 exist forced icm immediately immunoprecipitated inner kh notion nr5a2 oct3 overlap pluripotency polar pou5f1 preimplantation supporting te transcript transcriptase transcripts trophectoderm
Tagcloud (Intersection) ?