POGZ and TMBIM4

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		POGZ	TMBIM4
Description		pogo transposable element derived with ZNF domain	transmembrane BAX inhibitor motif containing 4
Image			No pdb structure
GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome Cytoplasm Cytosol Plasma Membrane Ciliary Basal Body	Golgi Membrane Endoplasmic Reticulum Membrane Golgi Apparatus Golgi Stack Membrane
	Molecular Function	Nucleic Acid Binding DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Calcium Channel Activity Protein Binding
	Biological Process	Double-strand Break Repair Via Homologous Recombination DNA Repair DNA Recombination DNA Damage Response Mitotic Sister Chromatid Cohesion Positive Regulation Of Transcription By RNA Polymerase II Cell Division Kinetochore Assembly	Apoptotic Process Locomotory Behavior Endoplasmic Reticulum Unfolded Protein Response Negative Regulation Of Apoptotic Process Negative Regulation Of Neuron Apoptotic Process Regulation Of Calcium-mediated Signaling Calcium Ion Transmembrane Transport
Pathways
Drugs
Diseases
GWAS		Blood trace element (Cu levels) ( 23720494) Body mass index ( 26426971) Gut microbiota (bacterial taxa, rank normal transformation method) ( 32572223) Pulse pressure ( 30578418)	Hip circumference adjusted for BMI ( 34021172) Pulse pressure ( 28498854)
Interacting Genes		87 interacting genes: A1CF ACTMAP AGR2 ANKRD10 AOC1 APP ATXN1 BANP BOLL C10orf55 CCDC136 CDK6 CERCAM CREB1 CRX DAB1 DAZAP2 DMXL1 DTX2 EID2B EIF3F EYA2 FAM168B FCSK FHL2 FNDC3B FOSB GABPB1 GMEB2 H3-4 HGS HIVEP1 HSF2BP HSPB2 HSPB2-C11orf52 HYI JMJD7 KLHDC7B KLHL26 KRTAP3-2 KRTAP6-2 KRTAP8-1 LITAF MBLAC1 MYO1B NFYA NFYC NHLRC4 NICN1 NRF1 ODAM PFDN5 PIDD1 PLEKHB2 PLIN2 POU2AF1 POU2F1 PRR20A PRR20B PRR20C PRR20D PRR20E QRICH1 RBFOX1 RBPMS RSPH1 SP1 SP3 SP4 SPATA12 SPRYD7 STH SUMO2 TBX19 TCIRG1 TMBIM4 TSC1 UFSP1 VAV2 VEZF1 VGLL3 ZBTB24 ZNF143 ZNF410 ZNF710 ZNF76 ZXDC	4 interacting genes: POGZ SLC22A1 VENTX VKORC1
Entrez ID		23126	51643
HPRD ID		11445	13032
Ensembl ID		ENSG00000143442	ENSG00000155957
Uniprot IDs		A0A8V8TQ67 Q7Z3K3	G3V1M2 G3XAA5 Q7Z782 Q9HC24
PDB IDs		2E72 2N3A 6EMP
Enriched GO Terms of Interacting Partners?		Positive Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of RNA Metabolic Process Positive Regulation Of DNA-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Protein Binding DNA Binding Positive Regulation Of Macromolecule Metabolic Process Nucleus DNA-binding Transcription Factor Activity Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process RNA Polymerase II Transcription Regulator Complex Protein-DNA Complex DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process CCAAT-binding Factor Complex Identical Protein Binding Sequence-specific DNA Binding Regulation Of Macromolecule Metabolic Process Sequence-specific Double-stranded DNA Binding Adult Locomotory Behavior	(R)-carnitine Transmembrane Transport Acetylcholine Transport Xenobiotic Metabolic Process Pyrimidine Nucleoside Transmembrane Transporter Activity (R)-carnitine Transmembrane Transporter Activity Metanephric Proximal Tubule Development Epinephrine Transport Norepinephrine:sodium Symporter Activity (R)-carnitine Transport Spermidine Transmembrane Transport Putrescine Transport Dopamine:sodium Symporter Activity Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity O-acyl-L-carnitine Transmembrane Transport Acetylcholine Transmembrane Transporter Activity Peptidyl-glutamic Acid Carboxylation Oxidoreductase Activity, Acting On CH Or CH2 Groups, Disulfide As Acceptor Vitamin-K-epoxide Reductase (warfarin-insensitive) Activity Vitamin-K-epoxide Reductase (warfarin-sensitive) Activity Spermidine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Thiamine Transmembrane Transport Carnitine Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Proximal Tubule Development Carnitine Transmembrane Transport Polyamine Transmembrane Transport Serotonin Uptake Norepinephrine Transport Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Organic Cation Transmembrane Transporter Activity Azole Transmembrane Transport Amino-acid Betaine Transport Quaternary Ammonium Group Transport Catecholamine Uptake Dopamine Uptake Prostaglandin Transport Serotonin Transport Metanephric Nephron Tubule Development Pyrimidine-containing Compound Transmembrane Transport Kinetochore Assembly Quinone Binding Vitamin K Metabolic Process
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