FOXO3 and SIRT1

  • Number of citations of the paper that reports this interaction (PMID 14976264)
  • 622
  • Data Source:
  • BioGRID (enzymatic study)
  • HPRD (two hybrid, in vivo, in vitro)

FOXO3

SIRT1

Gene Name forkhead box O3 sirtuin 1
Image
Gene Ontology Annotations Cellular Component
Molecular Function
Biological Process
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions 24 interactors: AKT1 ATM BTRC CDK6 CDT1 CHUK EP300 ERBB2IP ESR1 FOXG1 IKBKB MAPK1 MAPK6 NR1H2 NR1H3 SGK1 SIRT1 SMAD2 SMAD3 SMAD4 UBC VDR YWHAG YWHAZ 47 interactors: AKT1 ARNTL BCL11A BHLHE41 CDK6 CSNK2B CTTN EP300 ESRRA FOS FOXO1 FOXO3 GAPDH HES1 HEY2 HIC1 HIST1H1B HIST1H3A HNF4A IRS2 MAPK8 MAPT MYCN NBN NMNAT1 NR1H2 NR1H3 NR1H4 PARP1 PML PPARA PPARGC1A PSME3 RARA RELA RICTOR RRP8 SATB1 SETD7 SMAD7 SNW1 SREBF1 STK11 STK4 TP53 UBE2I VDR
Entrez ID 2309 23411
HPRD ID 04061 08381
Ensembl ID ENSG00000118689 ENSG00000096717
Uniprot IDs B4DVZ6 O43524 A8K128 B0QZ35 E9PC49 Q96EB6
PDB IDs 2K86 2LQH 2LQI 2UZK 4I5I
Enriched GO Terms of Interacting Partners?
Tagcloud ?
20b  34a  7e  actively  ccnd  ccne1  compromised  dysregulated  enterotoxin  exacerbation  infiltrating  let  lungs  mir  mirna  orchestrating  participating  pertaining  poisoning  ptgs2  runx1  saw  seb  silico  smad3  staphyloccocal  stringent  tbx21  tgfb 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Difference) ?
20b  34a  7e  actively  ccnd  ccne1  compromised  dysregulated  enterotoxin  exacerbation  infiltrating  let  lungs  mir  mirna  orchestrating  participating  pertaining  poisoning  ptgs2  runx1  saw  seb  silico  smad3  staphyloccocal  stringent  tbx21  tgfb 
1alpha  adipose  adrenergic  alternate  atgl  biogenesis  catalyzed  coactivator  coregulator  deacetylase  deacetylation  fatty  identifies  links  lipase  lipolysis  mediates  metabolism  nad  oxidative  partner  peroxisome  pgc  ppar  presumed  proliferator  promote  sirtuin  triglyceride 
Tagcloud (Intersection) ?