ERC1 and RAB6B

Number of citations of the paper that reports this interaction (PMID 11929610)
27

Data Source:
HPRD (two hybrid, in vitro)

		ERC1	RAB6B
Gene Name		ELKS/RAB6-interacting/CAST family member 1	RAB6B, member RAS oncogene family
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm IkappaB Kinase Complex Presynaptic Membrane Synapse	Golgi Membrane Golgi Apparatus Cytoplasmic Membrane-bounded Vesicle
	Molecular Function	Protein Binding Rab GTPase Binding PDZ Domain Binding Leucine Zipper Domain Binding	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding
	Biological Process	Regulation Of Transcription, DNA-templated I-kappaB Phosphorylation Multicellular Organismal Development Protein Transport Retrograde Transport, Endosome To Golgi Positive Regulation Of NF-kappaB Transcription Factor Activity	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport Rab Protein Signal Transduction Retrograde Transport, Endosome To Golgi
Pathways
Drugs
Diseases
GWAS		Bone mineral density ( 22504420)	Immune reponse to smallpox (secreted IL-1beta) ( 22610502)
Protein-Protein Interactions		7 interactors: APP ITSN2 PPFIA1 RAB6A RAB6B RIMS1 YWHAG	7 interactors: ACVR1 BMPR1B ERC1 KIF20A RABGAP1 SMAD1 TGFBR1
Entrez ID		23085	51560
HPRD ID		06181	11474
Ensembl ID		ENSG00000082805	ENSG00000154917
Uniprot IDs		Q8IUD2	Q9NRW1
PDB IDs			2E9S 2FE4 2FFQ
Enriched GO Terms of Interacting Partners?		Establishment Of Localization In Cell Cellular Localization Vesicle-mediated Transport Transport Glutamate Secretion Intracellular Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intracellular Protein Transport Intra-Golgi Vesicle-mediated Transport Rab Protein Signal Transduction Acid Secretion Retrograde Transport, Endosome To Golgi Dicarboxylic Acid Transport Secretion By Cell Cellular Protein Localization Protein Transport Neurotransmitter Secretion Establishment Of Protein Localization Synaptic Growth At Neuromuscular Junction Secretion Microtubule-based Transport Cytoskeleton-dependent Intracellular Transport Regulation Of Neurotransmitter Levels Collateral Sprouting In Absence Of Injury Minus-end-directed Organelle Transport Along Microtubule Peptidyl-cysteine Methylation Amino Acid Transport Signaling Regulation Of Synaptic Plasticity Neurotransmitter Transport Cell Communication Protein Localization Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Inhibitory Postsynaptic Membrane Potential Endosomal Transport Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Ras Protein Signal Transduction Axon Choice Point Recognition Calcium Ion-dependent Exocytosis Of Neurotransmitter Regulation Of Cellular Localization Golgi Vesicle Transport Negative Regulation Of Stress Fiber Assembly Neuron Remodeling Regulation Of Catalytic Activity Early Endosome To Golgi Transport Carboxylic Acid Transport Regulation Of Synaptic Transmission Organic Acid Transport Negative Regulation Of Actin Filament Bundle Assembly See more	Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Signal Transduction By Phosphorylation Positive Regulation Of Osteoblast Differentiation BMP Signaling Pathway Regulation Of Cartilage Development Positive Regulation Of Ossification Regulation Of Osteoblast Differentiation Pattern Specification Process Pathway-restricted SMAD Protein Phosphorylation Transforming Growth Factor Beta Receptor Signaling Pathway Pharyngeal System Development Protein Phosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus Response To Transforming Growth Factor Beta Gamete Generation Regulation Of Ossification Regulation Of Extrinsic Apoptotic Signaling Pathway Activin Receptor Signaling Pathway Sexual Reproduction Multicellular Organismal Reproductive Process Multicellular Organism Reproduction Phosphorylation Intracellular Signal Transduction Positive Regulation Of Cartilage Development Positive Regulation Of Bone Mineralization Cell Fate Commitment Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Biomineral Tissue Development Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Peptidyl-threonine Phosphorylation Regulation Of Pathway-restricted SMAD Protein Phosphorylation Reproduction Urogenital System Development Inflammatory Response Single Organism Reproductive Process Regulation Of Bone Mineralization Mesoderm Formation Mesoderm Morphogenesis Reproductive Process Endocardial Cushion Cell Fate Commitment Cell Cycle Heart Development Skeletal System Development Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Regulation Of Apoptotic Process Phosphate-containing Compound Metabolic Process Cellular Response To Growth Factor Stimulus Movement Of Cell Or Subcellular Component Mesenchymal Cell Development Response To Growth Factor See more
Tagcloud ?		betweenness calr calreticulin centrosome chance coagulation colocalized create cytoskeleton ddx3x dengue denv dsrna golga2 interacted mosquito ns3 ns5 occupy overlapping preferentially replication replicon starting throughput transmitted trip11 ube2i vast
Tagcloud (Difference) ?		betweenness calr calreticulin centrosome chance coagulation colocalized create cytoskeleton ddx3x dengue denv dsrna golga2 interacted mosquito ns3 ns5 occupy overlapping preferentially replication replicon starting throughput transmitted trip11 ube2i vast
Tagcloud (Intersection) ?