KDM4B and MED10

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		KDM4B	MED10
Gene Name		lysine (K)-specific demethylase 4B	mediator complex subunit 10
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Focal Adhesion Cell Junction	Nucleoplasm Mediator Complex
	Molecular Function	Zinc Ion Binding Dioxygenase Activity	RNA Polymerase II Transcription Cofactor Activity Protein Binding
	Biological Process	Chromatin Organization Transcription, DNA-templated Regulation Of Transcription, DNA-templated Chromatin Modification Oxidation-reduction Process	Transcription Initiation From RNA Polymerase II Promoter Gene Expression Stem Cell Maintenance Positive Regulation Of Transcription From RNA Polymerase II Promoter
Pathways		Chromatin modifying enzymes Chromatin organization HDMs demethylate histones	PPARA activates gene expression Fatty acid, triacylglycerol, and ketone body metabolism Metabolism of lipids and lipoproteins Generic Transcription Pathway Transcriptional regulation of white adipocyte differentiation Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
Drugs
Diseases
GWAS
Protein-Protein Interactions		2 interactors: H3F3C MED10	7 interactors: ESR1 ESR2 HNF4A KDM4B MOB4 NAP1L1 PEBP1
Entrez ID		23030	84246
HPRD ID		11056	14680
Ensembl ID		ENSG00000127663	ENSG00000133398
Uniprot IDs		F5GX28 O94953	Q9BTT4
PDB IDs
Enriched GO Terms of Interacting Partners?			Steroid Hormone Mediated Signaling Pathway Hormone-mediated Signaling Pathway Vagina Development Uterus Development Intracellular Estrogen Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus Female Genitalia Development Intracellular Receptor Signaling Pathway DNA-templated Transcription, Initiation Prostate Gland Epithelium Morphogenesis Prostate Gland Morphogenesis Sex Differentiation Genitalia Development Cellular Response To Organic Cyclic Compound Ovarian Follicle Development Prostate Gland Development Cellular Response To Lipid Intracellular Steroid Hormone Receptor Signaling Pathway Response To Steroid Hormone Ovulation Cycle Process Female Gonad Development Regulation Of Cell Proliferation Ovulation Cycle Cellular Response To Hormone Stimulus Development Of Primary Female Sexual Characteristics Chromatin Organization Prostate Epithelial Cord Elongation Negative Regulation Of Cell Growth Developmental Process Involved In Reproduction Gland Morphogenesis Positive Regulation Of Cholesterol Homeostasis Cellular Macromolecule Biosynthetic Process Response To Lipid Regulation Of Growth Hormone Receptor Signaling Pathway Epithelial Cell Maturation Involved In Prostate Gland Development Epithelial Cell Proliferation Involved In Mammary Gland Duct Elongation Positive Regulation Of Retinoic Acid Receptor Signaling Pathway Hormone-mediated Apoptotic Signaling Pathway Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Epithelial Cell Development Response To Organic Cyclic Compound Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Branch Elongation Involved In Mammary Gland Duct Branching Antral Ovarian Follicle Growth Gonad Development Response To Hormone Development Of Primary Sexual Characteristics Negative Regulation Of Growth
Tagcloud ?		c2c12 counter demethylase demethylases demethylation depleted driven evidences exogenous gradually interacts k9 luciferase methylated methyltransferases myoblast myod myogenic myogenin nonhistone obscure posttranslational presumably promoters represses rescues shrna skeletal tri	adapted bipolar colonies constituent desired ends front glycogen gsk3beta inositol integrations intergenic linc lithium mood msi2 mutated neuroblastoma pms1 presumed proliferate race readily salts screen stabilizing sy5y trapped variously
Tagcloud (Difference) ?		c2c12 counter demethylase demethylases demethylation depleted driven evidences exogenous gradually interacts k9 luciferase methylated methyltransferases myoblast myod myogenic myogenin nonhistone obscure posttranslational presumably promoters represses rescues shrna skeletal tri	adapted bipolar colonies constituent desired ends front glycogen gsk3beta inositol integrations intergenic linc lithium mood msi2 mutated neuroblastoma pms1 presumed proliferate race readily salts screen stabilizing sy5y trapped variously
Tagcloud (Intersection) ?