KDM4B

Description		lysine demethylase 4B
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm
	Molecular Function	Zinc Ion Binding Oxidoreductase Activity Histone Demethylase Activity Histone H3K9 Demethylase Activity Metal Ion Binding Dioxygenase Activity Histone H3K36 Demethylase Activity Histone H3K9me2/H3K9me3 Demethylase Activity
	Biological Process	Chromatin Organization Chromatin Remodeling Brain Development Regulation Of Gene Expression
Pathways		HDMs demethylate histones Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks Estrogen-dependent gene expression
Drugs
Diseases
GWAS		Granulocyte percentage of myeloid white cells ( 27863252) Hip circumference adjusted for BMI ( 34021172) Lymphocyte count ( 32888494) Lymphocyte percentage of white cells ( 27863252 32888494) Mean spheric corpuscular volume ( 32888494) Monocyte count ( 32888494) Monocyte percentage of white cells ( 27863252 32888494) Neutrophil count ( 32888494) Neutrophil percentage of white cells ( 27863252 32888494) Periodontitis (CDC/AAP) ( 24024966) Pulse pressure ( 30578418) Systemic lupus erythematosus ( 28714469) Systolic blood pressure ( 30224653) Triglyceride levels ( 32203549) Urate levels ( 31578528) Walking pace ( 33128006)
Novel Interacting Genes		1 novel interacting genes: TUBB4A
Interacting Genes		2 interacting genes: H3-5 MED10
Entrez ID		23030
HPRD ID		11056
Ensembl ID		ENSG00000127663
Uniprot IDs		A0A0C4DFL8 F5GX28 O94953
PDB IDs		4LXL 4UC4 7JM5 9H44
Enriched GO Terms of Interacting Partners?
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