ALDOC and SQLE

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ALDOC	SQLE
Gene Name		aldolase C, fructose-bisphosphate	squalene epoxidase
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Cytoskeleton Axon Extracellular Vesicular Exosome	Endoplasmic Reticulum Membrane Integral Component Of Membrane
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding	Squalene Monooxygenase Activity Flavin Adenine Dinucleotide Binding
	Biological Process	Response To Hypoxia Carbohydrate Metabolic Process Fructose Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Apoptotic Process Aging Pathogenesis Response To Organonitrogen Compound Response To Organic Cyclic Compound Fructose 1,6-bisphosphate Metabolic Process Epithelial Cell Differentiation Organ Regeneration Small Molecule Metabolic Process Protein Homotetramerization Protein Heterotetramerization	Cholesterol Biosynthetic Process Cellular Aromatic Compound Metabolic Process Response To Organic Substance Sterol Biosynthetic Process Small Molecule Metabolic Process Oxidation-reduction Process
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates	Regulation of cholesterol biosynthesis by SREBP (SREBF) Cholesterol biosynthesis Metabolism of lipids and lipoproteins Activation of gene expression by SREBF (SREBP)
Drugs			Naftifine Terbinafine Butenafine Ellagic Acid
Diseases
GWAS
Protein-Protein Interactions		6 interactors: ALDOA ATP6V1E1 LNX1 MAP2K3 PLD2 SQLE	3 interactors: ALDOC CREB3 ZNF641
Entrez ID		230	6713
HPRD ID		02386	11802
Ensembl ID		ENSG00000109107	ENSG00000104549
Uniprot IDs		P09972	Q14534 Q5HYI4 Q9UNR6
PDB IDs		1XFB
Enriched GO Terms of Interacting Partners?		Striated Muscle Contraction	Negative Regulation Of Ligand-dependent Nuclear Receptor Transcription Coactivator Activity Release From Viral Latency Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Unfolded Protein Response Fructose 1,6-bisphosphate Metabolic Process Positive Regulation Of Deacetylase Activity Establishment Of Viral Latency Positive Regulation Of Monocyte Chemotaxis Protein Heterotetramerization Regulation Of Monocyte Chemotaxis Positive Regulation Of Defense Response To Virus By Host Induction Of Positive Chemotaxis Fructose Metabolic Process Cytoplasmic Sequestering Of Transcription Factor Cytoplasmic Sequestering Of Protein Negative Regulation Of Endoplasmic Reticulum Stress-induced Intrinsic Apoptotic Signaling Pathway Regulation Of Defense Response To Virus By Host Positive Regulation Of Positive Chemotaxis Transcription From RNA Polymerase II Promoter Positive Regulation Of Transcription From RNA Polymerase II Promoter Involved In Cellular Response To Chemical Stimulus
Tagcloud ?		1c2 acads acat1 adipocyte adiposity aldolase altogether anxa2 aop1 apoa1 apparoach bisphosphate calorie droplet fabp4 ffa fructose glut4 hadh intensities ketoreductase proteome proteomics scaffolding spot tubb5 underscore vimentin	activin alp c1orf19 cdm chsy cobblestone cryab csrp1 dusp6 epas1 foetal gfpt2 grem1 hmgcs1 immunocytochemistry intermediary morphogenetic mt1x osr2 postn ppl rabgap1 sc4mol sox sox15 srgn stro therein wif1
Tagcloud (Difference) ?		1c2 acads acat1 adipocyte adiposity aldolase altogether anxa2 aop1 apoa1 apparoach bisphosphate calorie droplet fabp4 ffa fructose glut4 hadh intensities ketoreductase proteome proteomics scaffolding spot tubb5 underscore vimentin	activin alp c1orf19 cdm chsy cobblestone cryab csrp1 dusp6 epas1 foetal gfpt2 grem1 hmgcs1 immunocytochemistry intermediary morphogenetic mt1x osr2 postn ppl rabgap1 sc4mol sox sox15 srgn stro therein wif1
Tagcloud (Intersection) ?