ALDOC and PLD2

Number of citations of the paper that reports this interaction (PMID 11876650)
14

Data Source:
HPRD (in vitro)

		ALDOC	PLD2
Gene Name		aldolase C, fructose-bisphosphate	phospholipase D2
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Mitochondrion Cytosol Cytoskeleton Axon Extracellular Vesicular Exosome	Endoplasmic Reticulum Membrane Plasma Membrane Brush Border Membrane
	Molecular Function	Fructose-bisphosphate Aldolase Activity Protein Binding Cytoskeletal Protein Binding	Phospholipase D Activity Protein Binding Phosphatidylinositol Binding N-acylphosphatidylethanolamine-specific Phospholipase D Activity
	Biological Process	Response To Hypoxia Carbohydrate Metabolic Process Fructose Metabolic Process Glucose Metabolic Process Gluconeogenesis Glycolytic Process Apoptotic Process Aging Pathogenesis Response To Organonitrogen Compound Response To Organic Cyclic Compound Fructose 1,6-bisphosphate Metabolic Process Epithelial Cell Differentiation Organ Regeneration Small Molecule Metabolic Process Protein Homotetramerization Protein Heterotetramerization	G-protein Coupled Receptor Internalization Phospholipid Metabolic Process Phosphatidic Acid Biosynthetic Process Phosphatidylglycerol Biosynthetic Process Cytoskeleton Organization Small GTPase Mediated Signal Transduction Lipid Catabolic Process Synaptic Vesicle Recycling Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Small Molecule Metabolic Process Innate Immune Response Glycerophospholipid Biosynthetic Process
Pathways		Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Glycolysis Metabolism of carbohydrates	Synthesis of PA Metabolism of lipids and lipoproteins Synthesis of PG Role of phospholipids in phagocytosis Phospholipid metabolism Glycerophospholipid biosynthesis Fcgamma receptor (FCGR) dependent phagocytosis Innate Immune System
Drugs
Diseases
GWAS			Sphingolipid levels ( 22359512)
Protein-Protein Interactions		6 interactors: ALDOA ATP6V1E1 LNX1 MAP2K3 PLD2 SQLE	26 interactors: ACTB ACTN1 ALDOA ALDOC AMPH AQP3 ARF1 BIN1 CAV1 CSK DPYSL2 EGFR FYN GAPDH GM2A LCK MTOR OPRM1 PEA15 PIP5K1A PLCG1 PRKCA PRKCD RPTOR SRC STXBP1
Entrez ID		230	5338
HPRD ID		02386	03857
Ensembl ID		ENSG00000109107	ENSG00000129219
Uniprot IDs		P09972	I3L2C9 O14939
PDB IDs		1XFB
Enriched GO Terms of Interacting Partners?		Striated Muscle Contraction	Platelet Activation Blood Coagulation Regulation Of Body Fluid Levels Hemostasis Wound Healing Epidermal Growth Factor Receptor Signaling Pathway Response To Wounding ERBB Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Response To Stress Response To Organic Substance Endocytosis Cell Activation Vesicle-mediated Transport Enzyme Linked Receptor Protein Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Response To External Stimulus Neurotrophin Signaling Pathway Positive Regulation Of Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Immune System Process T Cell Costimulation Positive Regulation Of Intracellular Signal Transduction Innate Immune Response Response To Organonitrogen Compound Fc Receptor Signaling Pathway Immune Response-regulating Signaling Pathway Positive Regulation Of Immune System Process Protein Autophosphorylation Immune Response Regulation Of Cellular Localization Regulation Of Cell-cell Adhesion Defense Response Regulation Of Intracellular Signal Transduction Response To Growth Factor Immune System Process Regulation Of Signaling Positive Regulation Of Phosphorylation Negative Regulation Of Signaling Immune Response-activating Cell Surface Receptor Signaling Pathway Transport Response To Stimulus Positive Regulation Of Protein Modification Process Positive Regulation Of Catalytic Activity Cellular Response To Organonitrogen Compound Regulation Of Cell Activation
Tagcloud ?		1c2 acads acat1 adipocyte adiposity aldolase altogether anxa2 aop1 apoa1 apparoach bisphosphate calorie droplet fabp4 ffa fructose glut4 hadh intensities ketoreductase proteome proteomics scaffolding spot tubb5 underscore vimentin	1alpha abolished believed blocks butanol catalyzes ectopic elevate explored generating glioma hif hydrolysis messenger overexpressed pa pc phosphatidic phosphatidylcholine phospholipase pld1 responsive se secretion tumorigenesis u87 utilize vegf
Tagcloud (Difference) ?		1c2 acads acat1 adipocyte adiposity aldolase altogether anxa2 aop1 apoa1 apparoach bisphosphate calorie droplet fabp4 ffa fructose glut4 hadh intensities ketoreductase proteome proteomics scaffolding spot tubb5 underscore vimentin	1alpha abolished believed blocks butanol catalyzes ectopic elevate explored generating glioma hif hydrolysis messenger overexpressed pa pc phosphatidic phosphatidylcholine phospholipase pld1 responsive se secretion tumorigenesis u87 utilize vegf
Tagcloud (Intersection) ?