APC2

Gene Name		adenomatosis polyposis coli 2
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Golgi Membrane Cytoplasm Golgi Apparatus Cytoplasmic Microtubule Actin Filament Microtubule Cytoskeleton Catenin Complex Lamellipodium Membrane Perinuclear Region Of Cytoplasm
	Molecular Function	Protein Binding Beta-catenin Binding Microtubule Binding
	Biological Process	Wnt Signaling Pathway Negative Regulation Of Catenin Import Into Nucleus Negative Regulation Of Canonical Wnt Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-protein Interactions		5 interactors: AXIN2 CTNNB1 MAPRE1 MAPRE3 UBC
Entrez ID		10297
HPRD ID		09802
Ensembl ID		ENSG00000115266
Uniprot IDs		O95996
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Microtubule Plus-end Binding Regulation Of Centromeric Sister Chromatid Cohesion Positive Regulation Of Canonical Wnt Signaling Pathway Regulation Of Sister Chromatid Cohesion Positive Regulation Of Wnt Signaling Pathway Dorsal/ventral Axis Specification Regulation Of Canonical Wnt Signaling Pathway Positive Regulation Of Phosphorylation Positive Regulation Of Protein Modification Process Regulation Of Cell Cycle Cell Cycle Process Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Wnt Signaling Pathway Positive Regulation Of Cellular Protein Metabolic Process Organ Formation Positive Regulation Of Protein Metabolic Process Regulation Of Phosphorylation Positive Regulation Of Stem Cell Differentiation Cell Cycle Regulation Of Epithelial To Mesenchymal Transition Regulation Of Phosphorus Metabolic Process Regulation Of Chondrocyte Differentiation Positive Regulation Of Protein Binding Regulation Of Cell Cycle Process Regulation Of Chromosome Segregation Positive Regulation Of Type I Interferon Production Regulation Of Cartilage Development Positive Regulation Of Cell Death Regulation Of Type I Interferon Production Regulation Of Chondrocyte Development Axis Specification Mitotic Cell Cycle Process Regulation Of Cellular Protein Metabolic Process G2/M Transition Of Mitotic Cell Cycle Dorsal/ventral Pattern Formation Positive Regulation Of Binding Regulation Of Osteoblast Differentiation Cell Proliferation Positive Regulation Of Protein Phosphorylation Odontogenesis Mitotic Cell Cycle Regulation Of Protein Metabolic Process Regulation Of Microtubule Cytoskeleton Organization Regulation Of Protein Binding Negative Regulation Of Canonical Wnt Signaling Pathway Regulation Of Mismatch Repair Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus
Tagcloud ?		anaphase attenuation believed binds correlates cyclosome degradation demonstrates dispensable downregulated downregulation e3 implications knock ligase mdm2 oncoprotein polyubiquitination promoting proteasomal proto regulator rnai scaffold senescence shows stabilization ubiquitin