CD93 and COL4A6

Number of citations of the paper that reports this interaction (PubMedID 1377218)
0

Data Source:
HPRD (in vitro, in vivo)

		CD93	COL4A6
Description		CD93 molecule	collagen type IV alpha 6 chain
Image			No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Cell Surface Membrane Secretory Granule Membrane Cytoplasmic Vesicle Specific Granule Membrane Tertiary Granule Membrane Ficolin-1-rich Granule Membrane	Extracellular Region Collagen Trimer Collagen Type IV Trimer Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix
	Molecular Function	Complement Component C1q Complex Binding Calcium Ion Binding Protein Binding Carbohydrate Binding Signaling Receptor Activity	Extracellular Matrix Structural Constituent Protein Binding Extracellular Matrix Structural Constituent Conferring Tensile Strength
	Biological Process	Angiogenesis Phagocytosis Cell Adhesion Macrophage Activation Cell-cell Adhesion	Cell Adhesion Extracellular Matrix Organization Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Cellular Response To Amino Acid Stimulus
Pathways		Neutrophil degranulation	Collagen degradation Collagen degradation Fibronectin matrix formation Collagen biosynthesis and modifying enzymes Assembly of collagen fibrils and other multimeric structures Integrin cell surface interactions Integrin cell surface interactions Anchoring fibril formation Crosslinking of collagen fibrils Laminin interactions Laminin interactions Non-integrin membrane-ECM interactions ECM proteoglycans Collagen chain trimerization Attachment of bacteria to epithelial cells
Drugs
Diseases
GWAS		Liver enzyme levels (alanine transaminase) ( 24124411) Obesity-related traits ( 23251661) Venous thromboembolism ( 26888256 31676865)	Electrodermal activity ( 25387706)
Interacting Genes		25 interacting genes: ARHGAP15 BAG6 C1QA COL1A1 COL1A2 COL4A1 COL4A2 COL4A3 COL4A4 COL4A5 COL4A6 COPS5 F12 GIPC1 ITGB1 KIR2DL2 KNG1 MBL2 MMRN2 MSN MYD88 RANBP1 SCYL1 TENT5A UBQLN2	12 interacting genes: APP CD93 DCN FBLN2 FN1 HABP2 MAGEA6 MATN2 MMP9 NOTCH1 OSM SERPINE2
Entrez ID		22918	1288
HPRD ID		00396	02364
Ensembl ID		ENSG00000125810	ENSG00000197565
Uniprot IDs		Q9NPY3	A0A087WZY5 A8MXH5 A8VPY0 B2RTX6 B7ZMM7 F5H3Q5 Q14031
PDB IDs		8A59 8IVD
Enriched GO Terms of Interacting Partners?		Collagen Trimer Collagen Type IV Trimer Extracellular Matrix Structural Constituent Conferring Tensile Strength Collagen-activated Tyrosine Kinase Receptor Signaling Pathway Collagen-activated Signaling Pathway Extracellular Matrix Structural Constituent Extracellular Matrix Basement Membrane Endoplasmic Reticulum Lumen Extracellular Matrix Organization Extracellular Structure Organization Extracellular Region Platelet-derived Growth Factor Binding Response To Amino Acid Collagen Type I Trimer Enzyme-linked Receptor Protein Signaling Pathway Cellular Response To Amino Acid Stimulus Signal Transduction Signaling Receptor Binding Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Cell Surface Receptor Signaling Pathway Fibrillar Collagen Trimer Inflammatory Response Glomerular Basement Membrane Development Molecular Adaptor Activity Skin Morphogenesis Regulation Of Proteolysis Endothelial Cell Migration Misfolded Protein Binding Positive Regulation Of ERAD Pathway Regulation Of Response To Endoplasmic Reticulum Stress Symbiont Cell Surface Protease Binding Cell Migration Involved In Sprouting Angiogenesis Regulation Of ERAD Pathway Killing Of Cells Of Another Organism Angiogenesis Cellular Response To Low-density Lipoprotein Particle Stimulus Killing By Host Of Symbiont Cells Leukocyte Activation Leukocyte Activation Involved In Inflammatory Response Complement Activation, Classical Pathway Cellular Response To Vitamin E Protein Heterotrimerization Neuromuscular Junction Development Basement Membrane Organization Regulation Of Anatomical Structure Morphogenesis Regulation Of Wound Healing Zymogen Activation Cellular Response To Lipoprotein Particle Stimulus	Extracellular Region Extracellular Matrix Glycosaminoglycan Binding Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Positive Regulation Of Phosphatidylinositol 3-kinase/protein Kinase B Signal Transduction Peptidase Activator Activity Extracellular Space Regulation Of Cell Migration Regulation Of Locomotion Regulation Of Cell Motility Calcium Ion Binding Regulation Of Development, Heterochronic Positive Regulation Of Astrocyte Differentiation Regulation Of Timing Of Cell Differentiation Positive Regulation Of Cell Communication Positive Regulation Of Signaling Extracellular Matrix Structural Constituent Platelet Alpha Granule Signaling Receptor Binding Regulation Of Intracellular Signal Transduction Heparin Binding Negative Regulation Of Transport Extracellular Matrix Binding Regulation Of Astrocyte Differentiation Negative Regulation Of Signaling Negative Regulation Of Cell Communication Endodermal Cell Differentiation Regulation Of Cell Differentiation Positive Regulation Of Glial Cell Differentiation Amyloid-beta Complex Regulation Of Phosphorus Metabolic Process Growth Cone Lamellipodium Regulation Of Growth Regulation Of Developmental Process Regulation Of Response To Calcium Ion Regulation Of Cell Population Proliferation Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Cell Migration Positive Regulation Of Intracellular Signal Transduction Positive Regulation Of Cell Motility Positive Regulation Of Locomotion Extracellular Matrix Organization Positive Regulation Of Signal Transduction Dendrite Development Extracellular Structure Organization Regulation Of Cell-substrate Adhesion Positive Regulation Of Neurogenesis Response To Wounding Negative Regulation Of Epithelial Cell Differentiation
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