KLRK1 and RAE1

Number of citations of the paper that reports this interaction (PMID 11520456)
26

Data Source:
BioGRID (pull down)

		KLRK1	RAE1
Gene Name		killer cell lectin-like receptor subfamily K, member 1	ribonucleic acid export 1
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane	Nucleus Nuclear Envelope Nuclear Outer Membrane Nuclear Pore Nucleolus Cytoplasm Cytoskeleton
	Molecular Function	Receptor Activity Protein Binding Carbohydrate Binding	RNA Binding Microtubule Binding
	Biological Process	Signal Transduction Natural Killer Cell Activation Cell Differentiation T Cell Costimulation Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response	Mitotic Cell Cycle Carbohydrate Metabolic Process MRNA Export From Nucleus Mitotic Nuclear Envelope Disassembly Hexose Transport Pathogenesis Gene Expression Regulation Of Glucose Transport Glucose Transport Viral Process Viral Life Cycle Viral Transcription Cytokine-mediated Signaling Pathway Small Molecule Metabolic Process Transmembrane Transport Cellular Response To Organic Cyclic Compound
Pathways		DAP12 signaling DAP12 interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System Innate Immune System	Mitotic Prophase HIV Infection Nuclear import of Rev protein Regulatory RNA pathways Rev-mediated nuclear export of HIV RNA Nuclear Envelope Breakdown SLC-mediated transmembrane transport M Phase Influenza Life Cycle HIV Life Cycle Influenza Viral RNA Transcription and Replication Rev-mediated nuclear export of HIV RNA Myoclonic epilepsy of Lafora Glycogen storage diseases Transcriptional regulation by small RNAs Vpr-mediated nuclear import of PICs ISG15 antiviral mechanism Interferon Signaling Host Interactions of HIV factors Nuclear Pore Complex (NPC) Disassembly Regulation of Glucokinase by Glucokinase Regulatory Protein Cytokine Signaling in Immune system Interactions of Vpr with host cellular proteins Interactions of Rev with host cellular proteins Influenza Infection Hexose transport Cell Cycle, Mitotic Late Phase of HIV Life Cycle Antiviral mechanism by IFN-stimulated genes Viral Messenger RNA Synthesis Metabolism of carbohydrates Glucose transport
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-Protein Interactions		7 interactors: HCST MICB RAE1 RAET1E RAET1G TYROBP ULBP3	7 interactors: BUB1 DDX24 KLRC4 KLRK1 NUMA1 NUP98 NXF1
Entrez ID		22914	8480
HPRD ID		17240	11939
Ensembl ID		ENSG00000213809
Uniprot IDs		P26718	P78406
PDB IDs		1HYR 1KCG 1MPU	3MMY
Enriched GO Terms of Interacting Partners?		Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Leukocyte Mediated Immunity Antigen Processing And Presentation Innate Immune Response Regulation Of Immune Response T Cell Mediated Cytotoxicity Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Immune System Process Defense Response Antigen Processing And Presentation Of Peptide Antigen T Cell Mediated Immunity Immune System Process Leukocyte Activation Viral Process Cell Activation Response To Stress Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Osteoclast Development Gamma-delta T Cell Activation Adaptive Immune Response Neutrophil Activation Involved In Immune Response Negative Regulation Of Defense Response To Virus By Host Macrophage Activation Involved In Immune Response Lymphocyte Activation Neutrophil Activation Cytolysis Negative Regulation Of Defense Response To Virus Response To Stimulus Macrophage Activation Regulation Of Defense Response To Virus By Host Mitotic Nuclear Envelope Disassembly	Viral Process MRNA Transport Nucleus Organization Protein Import Into Nucleus, Docking RNA Transport Mitotic Cell Cycle Process RNA Localization Mitotic Cell Cycle Nuclear Pore Complex Assembly Nucleocytoplasmic Transport Cell Cycle Process Nuclear Transport Nuclear Pore Organization Poly(A)+ MRNA Export From Nucleus Pore Complex Assembly Mitotic Nuclear Division
Tagcloud ?		15rbeta aa alopecia areata autoreactive cd8 cytotoxic dermal effectors eliminated follicle gammac gwas hair ifn indicative infiltration jak jak1 janus nkg2d rational regrowth ruxolitinib signature signatures systemically therapeutically topical	constitutively cytosolic ddr effector emu enabling express immunoreceptor immunosurveillance irf3 killer ligands myc nk nkg2d nkg2dl occurrence originally recognizes relies revealing sensor sting sufficient tbk1 thereby transcript transfection upregulated
Tagcloud (Difference) ?		15rbeta aa alopecia areata autoreactive cd8 cytotoxic dermal effectors eliminated follicle gammac gwas hair ifn indicative infiltration jak jak1 janus rational regrowth ruxolitinib signature signatures systemically therapeutically topical	constitutively cytosolic ddr effector emu enabling express immunoreceptor immunosurveillance irf3 killer ligands myc nk nkg2dl occurrence originally recognizes relies revealing sensor sting sufficient tbk1 thereby transcript transfection upregulated
Tagcloud (Intersection) ?		nkg2d