KLRK1 and ULBP3

Number of citations of the paper that reports this interaction (PMID 11754823)
23

Data Source:
HPRD (in vitro)

		KLRK1	ULBP3
Gene Name		killer cell lectin-like receptor subfamily K, member 1	UL16 binding protein 3
Image
Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane	Plasma Membrane Anchored Component Of Plasma Membrane
	Molecular Function	Receptor Activity Protein Binding Carbohydrate Binding	Peptide Antigen Binding Natural Killer Cell Lectin-like Receptor Binding
	Biological Process	Signal Transduction Natural Killer Cell Activation Cell Differentiation T Cell Costimulation Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response	Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Viral Process Natural Killer Cell Activation Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response
Pathways		DAP12 signaling DAP12 interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System Innate Immune System	Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)	Alopecia areata ( 20596022) Metabolite levels (HVA/5-HIAA ratio) ( 23319000)
Protein-Protein Interactions		7 interactors: HCST MICB RAE1 RAET1E RAET1G TYROBP ULBP3	1 interactors: KLRK1
Entrez ID		22914	79465
HPRD ID		17240	16144
Ensembl ID		ENSG00000213809	ENSG00000131019
Uniprot IDs		P26718	B4DN91 Q9BZM4
PDB IDs		1HYR 1KCG 1MPU	1KCG
Enriched GO Terms of Interacting Partners?		Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Leukocyte Mediated Immunity Antigen Processing And Presentation Innate Immune Response Regulation Of Immune Response T Cell Mediated Cytotoxicity Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Immune System Process Defense Response Antigen Processing And Presentation Of Peptide Antigen T Cell Mediated Immunity Immune System Process Leukocyte Activation Viral Process Cell Activation Response To Stress Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Osteoclast Development Gamma-delta T Cell Activation Adaptive Immune Response Neutrophil Activation Involved In Immune Response Negative Regulation Of Defense Response To Virus By Host Macrophage Activation Involved In Immune Response Lymphocyte Activation Neutrophil Activation Cytolysis Negative Regulation Of Defense Response To Virus Response To Stimulus Macrophage Activation Regulation Of Defense Response To Virus By Host Mitotic Nuclear Envelope Disassembly	Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Positive Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Natural Killer Cell Mediated Immunity Natural Killer Cell Activation T Cell Costimulation Positive Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Cell Killing Regulation Of Leukocyte Mediated Cytotoxicity Positive Regulation Of Innate Immune Response Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Regulation Of Innate Immune Response Regulation Of T Cell Activation Positive Regulation Of Cell Activation Regulation Of Cell-cell Adhesion Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Lymphocyte Activation Regulation Of Cell Activation Leukocyte Activation Regulation Of Cell Adhesion Positive Regulation Of Immune Response Cell Activation Innate Immune Response
Tagcloud ?		15rbeta aa alopecia areata autoreactive cd8 cytotoxic dermal effectors eliminated follicle gammac gwas hair ifn indicative infiltration jak jak1 janus nkg2d rational regrowth ruxolitinib signature signatures systemically therapeutically topical	antimyeloma ark constitutively degranulation engagement erk expressions hdac histocompatibility immunotherapeutic killer lysis mic mica myeloma nk nkg2d nkp30 nkp44 nkp46 pd98059 ul16 ulbp1 ulbp2 ulbp4 upregulate valproic vpa
Tagcloud (Difference) ?		15rbeta aa alopecia areata autoreactive cd8 cytotoxic dermal effectors eliminated follicle gammac gwas hair ifn indicative infiltration jak jak1 janus rational regrowth ruxolitinib signature signatures systemically therapeutically topical	antimyeloma ark constitutively degranulation engagement erk expressions hdac histocompatibility immunotherapeutic killer lysis mic mica myeloma nk nkp30 nkp44 nkp46 pd98059 ul16 ulbp1 ulbp2 ulbp4 upregulate valproic vpa
Tagcloud (Intersection) ?		nkg2d