KLRK1

Gene Name		killer cell lectin-like receptor subfamily K, member 1
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Gene Ontology Annotations	Cellular Component	Plasma Membrane Integral Component Of Plasma Membrane Cell Surface Integral Component Of Membrane
	Molecular Function	Receptor Activity Protein Binding Carbohydrate Binding
	Biological Process	Signal Transduction Natural Killer Cell Activation Cell Differentiation T Cell Costimulation Innate Immune Response Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Regulation Of Immune Response
Pathways		DAP12 signaling DAP12 interactions Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell Adaptive Immune System Innate Immune System
Drugs
Diseases
GWAS		Obesity-related traits ( 23251661)
Protein-protein Interactions		7 interactors: HCST MICB RAE1 RAET1E RAET1G TYROBP ULBP3
Entrez ID		22914
HPRD ID		17240
Ensembl ID		ENSG00000213809
Uniprot IDs		P26718
PDB IDs		1HYR 1KCG 1MPU
Enriched GO Terms of Interacting Partners?		Natural Killer Cell Mediated Cytotoxicity Natural Killer Cell Mediated Immunity Leukocyte Mediated Cytotoxicity Leukocyte Mediated Immunity Antigen Processing And Presentation Innate Immune Response Regulation Of Immune Response T Cell Mediated Cytotoxicity Immune Response Antigen Processing And Presentation Of Peptide Antigen Via MHC Class I Regulation Of Immune System Process Defense Response Antigen Processing And Presentation Of Peptide Antigen T Cell Mediated Immunity Immune System Process Leukocyte Activation Viral Process Cell Activation Response To Stress Adaptive Immune Response Based On Somatic Recombination Of Immune Receptors Built From Immunoglobulin Superfamily Domains Regulation Of Osteoclast Development Gamma-delta T Cell Activation Adaptive Immune Response Neutrophil Activation Involved In Immune Response Negative Regulation Of Defense Response To Virus By Host Macrophage Activation Involved In Immune Response Lymphocyte Activation Neutrophil Activation Cytolysis Negative Regulation Of Defense Response To Virus Response To Stimulus Macrophage Activation Regulation Of Defense Response To Virus By Host Mitotic Nuclear Envelope Disassembly
Tagcloud ?		15rbeta aa alopecia areata autoreactive cd8 cytotoxic dermal effectors eliminated follicle gammac gwas hair ifn indicative infiltration jak jak1 janus nkg2d rational regrowth ruxolitinib signature signatures systemically therapeutically topical