ATG14 and EXOC1

Number of citations of the paper that reports this interaction (PMID 21241894)
45

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		ATG14	EXOC1
Gene Name		autophagy related 14	exocyst complex component 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytoplasm Autophagic Vacuole Axoneme Pre-autophagosomal Structure Membrane ER-mitochondrion Membrane Contact Site Phagocytic Vesicle Extrinsic Component Of Omegasome Membrane Extrinsic Component Of Pre-autophagosomal Structure Membrane	Exocyst Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding	Protein Binding
	Biological Process	Autophagic Vacuole Assembly Endosome To Lysosome Transport Positive Regulation Of Autophagy Posttranscriptional Regulation Of Gene Expression Macroautophagy Regulation Of Triglyceride Metabolic Process	Exocytosis Organelle Organization Protein Transport Cellular Protein Metabolic Process Membrane Organization
Pathways			Peptide hormone metabolism Cargo trafficking to the periciliary membrane Organelle biogenesis and maintenance Translocation of GLUT4 to the plasma membrane VxPx cargo-targeting to cilium Assembly of the primary cilium Insulin processing
Drugs
Diseases
GWAS			Cervical cancer ( 23817570)
Protein-Protein Interactions		2 interactors: BECN1 EXOC1	28 interactors: ATG14 CCDC88A CCDC93 CCSER2 CDC5L CEP295 COLEC12 DISC1 DST GOLGA4 KANSL1 KDM1A KIAA0226 KIAA1551 KIF5A LUC7L2 MACF1 NUF2 RALA RB1CC1 SFR1 SH3BP5 SPTAN1 SRGAP2 SYBU TRAF3IP1 TRIM9 TRIO
Entrez ID		22863	55763
HPRD ID		13820	07615
Ensembl ID		ENSG00000126775	ENSG00000090989
Uniprot IDs		Q6ZNE5	Q9NV70
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To Aluminum Ion Positive Regulation Of Mitochondrion Degradation CVT Pathway Response To Aluminum Ion Late Endosome To Vacuole Transport Regulation Of Mitochondrion Degradation Positive Regulation Of Macroautophagy Cellular Response To Nitrogen Starvation Response To Vitamin E Nucleophagy Beta-amyloid Metabolic Process Protein Targeting To Vacuole Cellular Response To Epidermal Growth Factor Stimulus Establishment Of Protein Localization To Vacuole Response To Epidermal Growth Factor Positive Regulation Of Autophagy Autophagic Vacuole Assembly Protein Transport Establishment Of Protein Localization Cellular Defense Response Lysosome Organization Macroautophagy Positive Regulation Of Mitochondrion Organization Vacuolar Transport Protein Localization Establishment Of Localization In Cell Regulation Of Mitochondrion Organization Vacuole Organization Response To Vitamin Cytokinesis Regulation Of Autophagy Cellular Localization Cellular Response To Metal Ion Cellular Response To Starvation Cellular Response To Inorganic Substance Peptide Metabolic Process Autophagy Defense Response To Virus Cellular Response To Nutrient Levels Response To Starvation	Golgi To Plasma Membrane Transport Movement Of Cell Or Subcellular Component Regulation Of Cellular Component Organization Locomotion Nervous System Development Post-Golgi Vesicle-mediated Transport Microtubule-based Process Regulation Of Cell Projection Organization Generation Of Neurons Regulation Of Autophagy TOR Signaling Organelle Organization Golgi To Plasma Membrane Protein Transport Neurogenesis Regulation Of Cell Size Regulation Of Cellular Component Size Chemotaxis Intracellular Signal Transduction Cellular Component Assembly Regulation Of Neuron Projection Development Vesicle-mediated Transport Autophagy Cellular Localization Axon Guidance Regulation Of Neurogenesis Positive Regulation Of Axon Extension Autophagic Vacuole Assembly Establishment Of Localization In Cell Regulation Of Primitive Erythrocyte Differentiation Lamellipodium Assembly Involved In Ameboidal Cell Migration Lamellipodium Assembly Microtubule Cytoskeleton Organization Cell Projection Organization Cell Communication Lamellipodium Organization Positive Regulation Of Neural Precursor Cell Proliferation Macroautophagy Cell Projection Morphogenesis Regulation Of Cell Development Extension Of A Leading Process Involved In Cell Motility In Cerebral Cortex Radial Glia Guided Migration Negative Regulation Of SNARE Complex Assembly Cell Part Morphogenesis Cerebral Cortex Radially Oriented Cell Migration Axonogenesis Regulation Of Axon Extension Regulation Of Neuron Differentiation Regulation Of Organelle Organization Cell Cycle Response To External Stimulus Golgi Vesicle Transport
Tagcloud ?		autophagic autophagosome autophagy beclin1 bvdv clean damaged degrade deprivation diarrhea doesn dysfunctional e1 envelope evolutionarily glycoproteins lc3 lentivirus macroautophagy maintains mdbk mechanistic nadl nutrient organelles principally puncta rns serves
Tagcloud (Difference) ?		autophagic autophagosome autophagy beclin1 bvdv clean damaged degrade deprivation diarrhea doesn dysfunctional e1 envelope evolutionarily glycoproteins lc3 lentivirus macroautophagy maintains mdbk mechanistic nadl nutrient organelles principally puncta rns serves
Tagcloud (Intersection) ?