RAB25 and RAB11FIP1

Number of citations of the paper that reports this interaction (PMID 11495908)
79

Data Source:
BioGRID (two hybrid)

		RAB25	RAB11FIP1
Gene Name		RAB25, member RAS oncogene family	RAB11 family interacting protein 1 (class I)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasmic Membrane-bounded Vesicle Pseudopodium Pseudopodium Membrane Cytoplasmic Vesicle Recycling Endosome Extracellular Vesicular Exosome	Cytoplasm Phagocytic Vesicle Membrane Intracellular Membrane-bounded Organelle Recycling Endosome
	Molecular Function	GTPase Activity Protein Binding GTP Binding GDP Binding Myosin V Binding	Rab GTPase Binding
	Biological Process	Epithelial Cell Morphogenesis Intracellular Protein Transport Exocytosis Positive Regulation Of Cell Proliferation Positive Regulation Of Epithelial Cell Migration Pseudopodium Organization Melanosome Transport Rab Protein Signal Transduction Regulation Of Vesicle-mediated Transport	Protein Transport Regulated Secretory Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		13 interactors: ACVR1 BMPR1B ITGB1 MED31 MYO5B OPTN RAB11FIP1 RAB11FIP2 RAB11FIP3 RAB11FIP5 SMAD4 SMURF2 TGFBR1	4 interactors: RAB11A RAB11B RAB25 RAB4A
Entrez ID		57111	80223
HPRD ID		06698	09787
Ensembl ID		ENSG00000132698	ENSG00000156675
Uniprot IDs		P57735	Q6WKZ4
PDB IDs		2OIL 3TSO
Enriched GO Terms of Interacting Partners?		Response To Transforming Growth Factor Beta BMP Signaling Pathway Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Transforming Growth Factor Beta Receptor Signaling Pathway Positive Regulation Of Pathway-restricted SMAD Protein Phosphorylation Cellular Response To Transforming Growth Factor Beta Stimulus Regulation Of Pathway-restricted SMAD Protein Phosphorylation Regulated Secretory Pathway Endocardial Cell Differentiation Insulin Secretion Involved In Cellular Response To Glucose Stimulus Endothelial Cell Activation Response To Growth Factor Positive Regulation Of SMAD Protein Import Into Nucleus Cell Fate Commitment Germ Cell Migration Negative Regulation Of Cell Proliferation Cellular Response To Organic Substance Regulation Of SMAD Protein Import Into Nucleus Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Pathway-restricted SMAD Protein Phosphorylation Negative Regulation Of Transmembrane Receptor Protein Serine/threonine Kinase Signaling Pathway Positive Regulation Of Signal Transduction Mesenchymal Cell Development Endocardium Development Atrioventricular Valve Morphogenesis Pharyngeal System Development Cardiocyte Differentiation Mesenchymal Cell Differentiation Atrioventricular Valve Development Protein Transport Mesoderm Development Vesicle-mediated Transport Establishment Of Protein Localization Cardiac Epithelial To Mesenchymal Transition Enzyme Linked Receptor Protein Signaling Pathway Pattern Specification Process Activin Receptor Signaling Pathway Transcription Initiation From RNA Polymerase II Promoter Ameboidal-type Cell Migration Cellular Localization Renal Water Homeostasis In Utero Embryonic Development Heart Development Gastrulation Regulation Of Cellular Response To Growth Factor Stimulus Heart Valve Morphogenesis Response To Organic Substance Heart Valve Development Cell Cycle Process Mesenchyme Development	Rab Protein Signal Transduction Ras Protein Signal Transduction Melanosome Transport Pigment Granule Transport Establishment Of Melanosome Localization Melanosome Localization Cellular Pigmentation Regulation Of Vesicle-mediated Transport Pigmentation Small GTPase Mediated Signal Transduction Intracellular Protein Transport Establishment Of Vesicle Localization Vesicle Localization Establishment Of Organelle Localization Cellular Protein Localization Exocytosis Protein Transport Establishment Of Protein Localization Intracellular Transport Organelle Localization Secretion By Cell Intracellular Signal Transduction Protein Localization Establishment Of Localization In Cell Positive Regulation Of Epithelial Cell Migration Secretion Cellular Localization Multivesicular Body Assembly Regulation Of Multivesicular Body Size Membrane Organization Regulation Of Epithelial Cell Migration Constitutive Secretory Pathway Multivesicular Body Organization Endosomal Transport Regulation Of Endosome Size Pseudopodium Organization Establishment Of Protein Localization To Membrane Exosomal Secretion Insulin Secretion Involved In Cellular Response To Glucose Stimulus Vesicle-mediated Transport Positive Regulation Of Cell Migration Positive Regulation Of Cell Motility Cellular Response To Acidic PH Plasma Membrane To Endosome Transport Astral Microtubule Organization Positive Regulation Of Cellular Component Movement Positive Regulation Of Locomotion Protein Localization To Membrane Regulation Of Endocytic Recycling Receptor Recycling
Tagcloud ?		acini acquire alpha5beta1 basement cargo clic3 com compartments concert correspondingly drives endosomal endosomes integrin invasiveness matrigel mcf10dcis metalloproteinase mmp mmp14 mt1 opposes organotypic plane plugs predicts recycling trafficking transferred	11q13 12p13 17q12 20q13 20q13co 20q13z 8p12 8q24 amplification amplifications amplified aurka bac centered fgfr1 frequencies histoclinical impacts loci mybl2 never nol1 organized probes recurrently spanning subregions tma znf217
Tagcloud (Difference) ?		acini acquire alpha5beta1 basement cargo clic3 com compartments concert correspondingly drives endosomal endosomes integrin invasiveness matrigel mcf10dcis metalloproteinase mmp mmp14 mt1 opposes organotypic plane plugs predicts recycling trafficking transferred	11q13 12p13 17q12 20q13 20q13co 20q13z 8p12 8q24 amplification amplifications amplified aurka bac centered fgfr1 frequencies histoclinical impacts loci mybl2 never nol1 organized probes recurrently spanning subregions tma znf217
Tagcloud (Intersection) ?