ZNF652 and CBFA2T2

Number of citations of the paper that reports this interaction (PubMedID 16966434)
0

Data Source:
HPRD (in vivo)

		ZNF652	CBFA2T2
Description		zinc finger protein 652	CBFA2/RUNX1 partner transcriptional co-repressor 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II	Negative Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Epithelial Cell Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of DNA-templated Transcription Intestinal Epithelial Cell Differentiation
Pathways			Specification of primordial germ cells
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 34103634 29273806 32296059 31959851 30929738 31619474 31361310) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 30929738 31036433) Asthma (moderate or severe) ( 30552067) Atopic dermatitis ( 23727859) Blood pressure ( 21909110) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Cancer ( 29299148) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878 27618452 27618447 28739976 19430483) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Egg allergy (maternal genetic effects) ( 29489655) Eosinophil count ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Height ( 20881960) Intraocular pressure ( 29785010) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Myocardial infarction ( 33532862) Neutrophil percentage of granulocytes ( 27863252) Prostate cancer ( 23535732 21602798 34012061) Refractive error ( 32231278) Sex hormone-binding globulin levels ( 22829776) Systolic blood pressure ( 27841878 27618452) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Thyroid stimulating hormone levels ( 32769997) Triglyceride levels ( 32203549)	Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Triglyceride levels ( 32203549)
Interacting Genes		4 interacting genes: CBFA2T2 CBFA2T3 RUNX1T1 TRIM14	34 interacting genes: APP ATN1 ATXN1L BAG4 CBFA2T3 CBFB CEP83 FBXL19 GTF2E1 ID3 KIFC3 KRTAP13-2 LBP MAGEA6 MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 PEX14 PHAF1 PRDM6 RERE RUNX1 SIKE1 SIN3A SORBS3 TAL2 TCF4 TCP1 ZC2HC1A ZNF652
Entrez ID		22834	9139
HPRD ID		18362	04721
Ensembl ID		ENSG00000198740	ENSG00000078699
Uniprot IDs		A8K9F2 D6RF85 Q9Y2D9	O43439
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Corepressor Activity DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding Glycosylated Region Protein Binding Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Protein Binding Involved In Heterotypic Cell-cell Adhesion Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Negative Regulation Of T Cell Migration Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Matrix Metallopeptidase Secretion Intestinal Epithelial Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process RNA Metabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Lymphocyte Migration Negative Regulation Of Macrophage Migration Positive Regulation Of Transforming Growth Factor Beta Production Negative Regulation Of Macrophage Activation Negative Regulation Of Neuroinflammatory Response Negative Regulation Of Viral Transcription Regulation Of Viral Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of ATP Metabolic Process Metal Ion Binding Granulocyte Differentiation Regulation Of Aerobic Respiration Positive Regulation Of Macrophage Activation Protein K48-linked Deubiquitination	Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Corepressor Activity Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Core-binding Factor Complex Regulation Of MiRNA Transcription Negative Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Positive Regulation Of Neuron Differentiation Regulation Of Neuron Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Transcription Regulator Inhibitor Activity Nucleus Histone Deacetylase Complex Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Activation Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Protein Binding Transcription Repressor Complex Chromatin Binding Protein Dimerization Activity Regulation Of ATP Metabolic Process DNA Binding Negative Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus Regulation Of Purine Nucleotide Metabolic Process Response To Catecholamine Neuron Differentiation Regulation Of CD8-positive, Alpha-beta T Cell Activation Negative Regulation Of Glycolytic Process Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of ATP Metabolic Process Amyloid-beta Complex
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?