ZNF652

Description		zinc finger protein 652
Image		No pdb structure
GO Annotations	Cellular Component	Nucleus
	Molecular Function	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Allergic disease (asthma, hay fever or eczema) ( 29083406) Asthma ( 34103634 29273806 32296059 31959851 30929738 31619474 31361310) Asthma (adult onset) ( 30929738) Asthma (childhood onset) ( 30929738 31036433) Asthma (moderate or severe) ( 30552067) Atopic dermatitis ( 23727859) Blood pressure ( 21909110) Body fat distribution (arm fat ratio) ( 30664634) Body fat distribution (leg fat ratio) ( 30664634) Body fat distribution (trunk fat ratio) ( 30664634) Brain morphology (MOSTest) ( 32665545) Cancer ( 29299148) Coronary artery disease ( 29212778) Diastolic blood pressure ( 27841878 27618452 27618447 28739976 19430483) Diastolic blood pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Diastolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Egg allergy (maternal genetic effects) ( 29489655) Eosinophil count ( 27863252) Eosinophil percentage of granulocytes ( 27863252) Eosinophil percentage of white cells ( 27863252) Height ( 20881960) Intraocular pressure ( 29785010) Mean arterial pressure x alcohol consumption (light vs heavy) interaction (2df test) ( 29912962) Mean arterial pressure x alcohol consumption interaction (2df test) ( 29912962) Mean reticulocyte volume ( 32888494) Multiple sclerosis ( 31604244) Myocardial infarction ( 33532862) Neutrophil percentage of granulocytes ( 27863252) Prostate cancer ( 23535732 21602798 34012061) Refractive error ( 32231278) Sex hormone-binding globulin levels ( 22829776) Systolic blood pressure ( 27841878 27618452) Systolic blood pressure x alcohol consumption interaction (2df test) ( 29912962) Thyroid stimulating hormone levels ( 32769997) Triglyceride levels ( 32203549)
Novel Interacting Genes		1 novel interacting genes: CD200
Interacting Genes		4 interacting genes: CBFA2T2 CBFA2T3 RUNX1T1 TRIM14
Entrez ID		22834
HPRD ID		18362
Ensembl ID		ENSG00000198740
Uniprot IDs		A8K9F2 D6RF85 Q9Y2D9
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription Corepressor Activity DNA-templated Transcription Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Zinc Ion Binding Glycosylated Region Protein Binding Nucleobase-containing Compound Biosynthetic Process Negative Regulation Of Macromolecule Biosynthetic Process Protein Binding Involved In Heterotypic Cell-cell Adhesion Negative Regulation Of Biosynthetic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Regulation Of Gene Expression Negative Regulation Of T Cell Migration Negative Regulation Of Matrix Metallopeptidase Secretion Negative Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Matrix Metallopeptidase Secretion Intestinal Epithelial Cell Differentiation Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Macromolecule Biosynthetic Process RNA Metabolic Process Negative Regulation Of Glycolytic Process Negative Regulation Of Lymphocyte Migration Negative Regulation Of Macrophage Migration Positive Regulation Of Transforming Growth Factor Beta Production Negative Regulation Of Macrophage Activation Negative Regulation Of Neuroinflammatory Response Negative Regulation Of Viral Transcription Regulation Of Viral Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of ATP Metabolic Process Metal Ion Binding Granulocyte Differentiation Regulation Of Aerobic Respiration Positive Regulation Of Macrophage Activation Protein K48-linked Deubiquitination
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