RASA3 and GNB2L1

Number of citations of the paper that reports this interaction (PMID 11350068)
8

Data Source:
HPRD (in vivo)

		RASA3	GNB2L1
Gene Name		RAS p21 protein activator 3	guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Intrinsic Component Of The Cytoplasmic Side Of The Plasma Membrane	Phagocytic Cup Nucleus Cytoplasm Mitochondrion Cytosol Cytoskeleton Small Ribosomal Subunit Dendrite Midbody Neuronal Cell Body Perikaryon Perinuclear Region Of Cytoplasm Extracellular Vesicular Exosome
	Molecular Function	GTPase Activator Activity Ras GTPase Activator Activity Calcium-release Channel Activity Metal Ion Binding	Protein Kinase C Binding Receptor Binding Protein Binding Ion Channel Inhibitor Activity Cysteine-type Endopeptidase Activator Activity Involved In Apoptotic Process Enzyme Binding Protein Phosphatase Binding Protein Tyrosine Kinase Inhibitor Activity Receptor Tyrosine Kinase Binding Protein Complex Scaffold SH2 Domain Binding Protein Homodimerization Activity Poly(A) RNA Binding
	Biological Process	Signal Transduction Positive Regulation Of Ras GTPase Activity Intracellular Signal Transduction Negative Regulation Of Ras Protein Signal Transduction Calcium Ion Transmembrane Transport	Osteoblast Differentiation Positive Regulation Of Protein Phosphorylation Activation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Cell Cycle Gastrulation Negative Regulation Of Gene Expression Viral Process Negative Regulation Of Translation Negative Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Growth Positive Regulation Of Cell Migration Positive Regulation Of CAMP Catabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of Protein Homooligomerization Regulation Of Protein Localization Positive Regulation Of Apoptotic Process Positive Regulation Of GTPase Activity Rhythmic Process Negative Regulation Of Phagocytosis Regulation Of Cell Division Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Cell Cycle Negative Regulation Of Protein Kinase B Signaling Positive Regulation Of Mitochondrial Depolarization Negative Regulation Of Protein Tyrosine Kinase Activity Regulation Of Establishment Of Protein Localization To Plasma Membrane Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Regulation Of Establishment Of Cell Polarity Positive Regulation Of Gastrulation Positive Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		5 interactors: APP FES GNB2L1 HCK RAP1A	86 interactors: ADH1B ADRB2 AGTRAP AR AURKB BCL2L11 CCNA1 CDKN1A CHERP CSF2RB DDX19B DGCR14 DNM1 DYNLL1 EIF6 EPOR FBXW7 FYN GABRB3 GNB1 GOLM1 GRAP2 GRIN2B HABP4 HIF1A HNRNPH2 IFNAR1 IFNAR2 IFNR IGF1R IK IL2RB IL4R IL7R INSR ITGB1 ITGB2 ITGB5 ITGB7 JAK1 LARP4B LRP12 MAPK6 MKRN2 NFATC1 NR3C1 NSMAF PABPC1 PDE4D PLCG1 PLEC PRKAB2 PRKCA PRKCB PRKCD PRKCE PRKD1 PRPF31 PTN PTOV1 PTPRM RASA1 RASA3 RB1 RHOA SAT1 SLC27A6 SLC6A3 SRC SREK1 ST7 STAT1 STAT3 SUMO4 SYT1 TARDBP TBXA2R TCEB1 TCEB2 TNFRSF1A TP63 TP73 TSC22D4 TUBB TYK2 WDR83
Entrez ID		22821	10399
HPRD ID		05537	01503
Ensembl ID		ENSG00000185989	ENSG00000204628
Uniprot IDs		F8W6X8 Q14644	E9KL35 P63244
PDB IDs			3J3A 4AOW
Enriched GO Terms of Interacting Partners?		Regulation Of Vesicle-mediated Transport Positive Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Protein Complex Assembly Positive Regulation Of Cellular Component Biogenesis Peptidyl-tyrosine Autophosphorylation Regulation Of Actin Cytoskeleton Reorganization Regulation Of Protein Complex Assembly Cell Differentiation Regulation Of Protein Tyrosine Kinase Activity Regulation Of Phagocytosis Regulation Of Neuron Differentiation Respiratory Burst After Phagocytosis Regulation Of Cellular Component Organization Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Neurogenesis Positive Regulation Of Protein Polymerization Regulation Of Protein Kinase Activity Regulation Of Kinase Activity Innate Immune Response Positive Regulation Of Peptidase Activity Anatomical Structure Development Leukocyte Migration Involved In Immune Response Synaptic Growth At Neuromuscular Junction Positive Regulation Of CAMP Catabolic Process Regulation Of Exocytosis Regulation Of Cell Development Regulation Of Cell Shape Enzyme Linked Receptor Protein Signaling Pathway Collateral Sprouting In Absence Of Injury Negative Regulation Of Hydrogen Peroxide-induced Neuron Death Regulation Of Endocytosis Platelet Activation Developmental Process Positive Regulation Of Cytoskeleton Organization Regulation Of Peptidyl-tyrosine Phosphorylation Regulation Of Cellular Localization Positive Regulation Of Hydrolase Activity Protein Autophosphorylation Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Regulation Of Protein Phosphorylation Positive Regulation Of Neuron Projection Development Positive Regulation Of Cellular Protein Metabolic Process Collateral Sprouting Axon Midline Choice Point Recognition Respiratory Burst Involved In Defense Response Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Regulation Of Translation Positive Regulation Of Protein Metabolic Process Axon Choice Point Recognition Negative Regulation Of Oxidative Stress-induced Neuron Death	Signaling Cell Communication Cellular Response To Stimulus Signal Transduction Response To Stimulus Cell Surface Receptor Signaling Pathway Cellular Response To Organic Substance Intracellular Signal Transduction Response To Organic Substance Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Regulation Of Signaling Regulation Of Signal Transduction Response To External Stimulus Defense Response Viral Process Response To Stress Immune System Process Regulation Of Immune Response Regulation Of Body Fluid Levels Regulation Of Cell Proliferation Regulation Of Immune System Process Response To Abiotic Stimulus Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Protein Localization Positive Regulation Of Signal Transduction Regulation Of Cellular Localization Response To Cytokine Regulation Of Cell Death Regulation Of Cellular Process Cytokine-mediated Signaling Pathway Cellular Response To Cytokine Stimulus Platelet Activation Innate Immune Response Immune Response Regulation Of Phosphorylation Blood Coagulation Regulation Of Apoptotic Process Hemostasis Regulation Of Protein Phosphorylation Positive Regulation Of Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Cell Cycle Positive Regulation Of Transport Peptidyl-tyrosine Autophosphorylation Cellular Process Neurotrophin TRK Receptor Signaling Pathway Developmental Process Regulation Of Angiogenesis Positive Regulation Of Cellular Metabolic Process
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