RASA3 and TUBGCP3

Data Source: HiPPIP (Novel)

		RASA3	TUBGCP3
Name		RAS p21 protein activator 3	tubulin gamma complex component 3
Structure		No pdb structure
GO Annotations	Cellular Component	Cytosol Plasma Membrane Cytoplasmic Side Of Plasma Membrane Membrane	Spindle Pole Gamma-tubulin Complex Cytoplasm Centrosome Centriole Microtubule Organizing Center Spindle Polar Microtubule Cytosol Cytoskeleton Microtubule Membrane
	Molecular Function	GTPase Activator Activity Calcium Channel Regulator Activity Zinc Ion Binding Metal Ion Binding	Structural Molecule Activity Structural Constituent Of Cytoskeleton Protein Binding Gamma-tubulin Binding Microtubule Minus-end Binding
	Biological Process	Response To Stress Signal Transduction Platelet Activation Intracellular Signal Transduction Negative Regulation Of Ras Protein Signal Transduction Regulation Of Intracellular Signal Transduction	Microtubule Cytoskeleton Organization Mitotic Cell Cycle Microtubule Nucleation Single Fertilization Cytoplasmic Microtubule Organization Spindle Assembly Meiotic Cell Cycle
Pathways		Regulation of RAS by GAPs	Recruitment of mitotic centrosome proteins and complexes Recruitment of NuMA to mitotic centrosomes
GWAS		Anti-Epstein-Barr virus IgG seropositivity ( 33204752 ) Cutaneous melanoma or hair colour ( 32341527 ) Lymphocyte count ( 32888494 ) Lymphocyte percentage of white cells ( 32888494 ) Phoneme awareness ( 30741946 ) Platelet distribution width ( 32888494 ) White blood cell count ( 32888494 ) Whole brain grey matter density ( 31530798 )	Glycated hemoglobin levels ( 20858683 )
Novel Interactors		1 novel interactors: TUBGCP3	5 novel interactors: ARTN CDC16 LRBA PROZ RASA3
Interacting Genes		5 interacting genes: APP FES HCK RACK1 RAP1A	7 interacting genes: AKAP9 CEBPA DNAJB6 IMMT PCNT TUBG1 TUBG2
Entrez ID		22821	10426
HPRD ID		05537	10289
Ensembl ID		ENSG00000185989	ENSG00000126216
Uniprot IDs		Q14644	A0A087WU06 B4DYP7 Q96CW5
PDB IDs		Not available	6V6B 6V6S 6X0U 7AS4 7QJ0 7QJ1 7QJ2 7QJ3 7QJ4 7QJ5 7QJ6 7QJ7 7QJ8 7QJ9 7QJA 7QJB 7QJC 7QJD 8Q62 8RX1 8VRD 8VRJ 8VRK
GO Terms Enriched among Interactors		Regulation Of Vesicle-mediated Transport Regulation Of Endocytosis Regulation Of Phagocytosis Positive Regulation Of Cellular Component Organization Positive Regulation Of Supramolecular Fiber Organization Positive Regulation Of Protein-containing Complex Assembly Regulation Of Transport Positive Regulation Of Phosphate Metabolic Process Cellular Response To Oxygen-containing Compound Response To Nerve Growth Factor Response To Growth Factor Cellular Response To Growth Factor Stimulus Cellular Response To Nerve Growth Factor Stimulus Peptidyl-tyrosine Phosphorylation Non-membrane Spanning Protein Tyrosine Kinase Activity Neuron Projection Cellular Response To CAMP Positive Regulation Of Immune System Process Regulation Of Supramolecular Fiber Organization Amyloid-beta Complex Regulation Of Cellular Component Organization Signaling Receptor Binding Growth Cone Lamellipodium Regulation Of Developmental Process Regulation Of Response To Calcium Ion Cell Body Amylin Binding Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Protein Polymerization Anchoring Junction Regulation Of Protein-containing Complex Assembly Cellular Response To Lipid Response To CAMP Positive Regulation Of GTPase Activity Regulation Of Biological Quality Regulation Of Response To Endoplasmic Reticulum Stress Positive Regulation Of Developmental Process Positive Regulation Of Cellular Component Biogenesis Acetylcholine Receptor Activator Activity Regulation Of Phosphorus Metabolic Process Defense Response To Gram-positive Bacterium Lipoprotein Particle Positive Regulation Of Protein Import Cytoplasmic Side Of Plasma Membrane Regulated Exocytosis Positive Regulation Of Hydrolase Activity Response To Antineoplastic Agent IRE1-RACK1-PP2A Complex Negative Regulation Of Translational Frameshifting Protein Autophosphorylation	Microtubule Nucleation Microtubule Nucleator Activity Gamma-tubulin Ring Complex Gamma-tubulin Complex Mitotic Spindle Organization Centrosome Microtubule Cytoskeleton Organization Involved In Mitosis Meiotic Spindle Organization Pericentriolar Material Spindle Organization Microtubule Cytoskeleton Organization Mitotic Sister Chromatid Segregation Cytoskeleton Organization Sister Chromatid Segregation Spindle Microtubule Spindle Organelle Organization Nuclear Chromosome Segregation RNA Polymerase I Transcription Regulatory Region Sequence-specific DNA Binding Cytoplasmic Microtubule Cytoplasmic Microtubule Organization Response To Vitamin B2 C/EBP Complex Microtubule CHOP-C/EBP Complex Microtubule Organizing Center Cytoskeleton Microtubule-based Process Peyer's Patch Morphogenesis Syncytiotrophoblast Cell Differentiation Involved In Labyrinthine Layer Development Chorion Development Dendritic Branch White Fat Cell Proliferation Glial Cell-derived Neurotrophic Factor Receptor Binding