ATXN7L1 and PHF1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ATXN7L1	PHF1
Gene Name		ataxin 7-like 1	PHD finger protein 1
Image		No pdb structure
Gene Ontology Annotations	Cellular Component		Nucleus Nucleoplasm Cytoplasm Microtubule Organizing Center ESC/E(Z) Complex Site Of Double-strand Break
	Molecular Function		Sequence-specific DNA Binding Transcription Factor Activity Zinc Ion Binding Methylated Histone Binding
	Biological Process		Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cellular Response To DNA Damage Stimulus Gene Expression Chromatin Modification Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Histone H3-K27 Methylation Positive Regulation Of Histone H3-K27 Methylation
Pathways			Epigenetic regulation of gene expression PRC2 methylates histones and DNA
Drugs
Diseases
GWAS		Alzheimer's disease (late onset) ( 22881374) Dental caries ( 23064961) Obesity-related traits ( 23251661)
Protein-Protein Interactions		5 interactors: KRT31 KRTAP10-9 PHF1 SP4 SSPO	22 interactors: ATXN7L1 BIRC7 CALCOCO2 EZH2 HIST1H3A HIST1H3B HIST1H3C HIST1H3E HIST1H3F HIST1H3G HIST1H3H HIST1H3I HIST1H3J HSD17B14 NAB2 NEK6 PDLIM7 RBPMS TFCP2 THAP1 TRIM23 VAC14
Entrez ID		222255	5252
HPRD ID		12508	04195
Ensembl ID		ENSG00000146776	ENSG00000112511
Uniprot IDs		A4D0Q2 Q9ULK2	O43189
PDB IDs			2E5P 2M0O 4HCZ
Enriched GO Terms of Interacting Partners?			DNA Replication-dependent Nucleosome Assembly DNA Methylation On Cytosine Chromatin Silencing At RDNA Regulation Of Gene Silencing DNA Methylation Chromatin Silencing Negative Regulation Of Gene Expression, Epigenetic DNA Modification Gene Silencing Nucleosome Assembly Regulation Of Gene Expression, Epigenetic Chromatin Assembly Nucleosome Organization Chromatin Assembly Or Disassembly Protein-DNA Complex Assembly DNA Packaging Methylation DNA Conformation Change Wound Healing Blood Coagulation Hemostasis Response To Wounding Chromatin Organization Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Body Fluid Levels Cellular Macromolecular Complex Assembly Negative Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Chromosome Organization Protein Complex Assembly DNA Metabolic Process Negative Regulation Of Cellular Metabolic Process Gene Expression Regulation Of Metabolic Process Response To Stress Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Cellular Component Assembly Regulation Of RNA Metabolic Process Organelle Organization Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process
Tagcloud ?			12e8 albeit at180 axon dendrite enter enters fyn glutamic map2 p301l pseudophosphorylated pseudophosphorylation replacements s235 s262 s356 s396 s404 s422 shaft shares spine spines synaptosomal t231 tau tau1 vastly
Tagcloud (Difference) ?			12e8 albeit at180 axon dendrite enter enters fyn glutamic map2 p301l pseudophosphorylated pseudophosphorylation replacements s235 s262 s356 s396 s404 s422 shaft shares spine spines synaptosomal t231 tau tau1 vastly
Tagcloud (Intersection) ?