H2AC1 and ANP32B

Number of citations of the paper that reports this interaction (PubMedID 18039846)
53

Data Source:
BioGRID (pull down)

		H2AC1	ANP32B
Description		H2A clustered histone 1	acidic nuclear phosphoprotein 32 family member B
Image
GO Annotations	Cellular Component	Chromosome, Telomeric Region Nucleosome Female Germ Cell Nucleus Nucleus Chromosome Extracellular Exosome	Nucleus Nucleoplasm Nucleolus Cytoplasm Extracellular Exosome
	Molecular Function	DNA Binding Structural Constituent Of Chromatin Protein Heterodimerization Activity	Protein Binding Histone Binding RNA Polymerase Binding
	Biological Process	Chromatin Organization Heterochromatin Formation	Vasculature Development Nucleosome Assembly Ventricular System Development Regulation Of Apoptotic Process Negative Regulation Of Apoptotic Process Negative Regulation Of Cell Differentiation Positive Regulation Of Protein Export From Nucleus Inner Ear Development Roof Of Mouth Development
Pathways		HDACs deacetylate histones HATs acetylate histones HATs acetylate histones RMTs methylate histone arginines UCH proteinases Ub-specific processing proteases Metalloprotease DUBs HCMV Early Events HCMV Late Events
Drugs
Diseases
GWAS			Alopecia areata ( 25608926) Coronary artery disease ( 29212778) Eosinophil count ( 32888494) Immature fraction of reticulocytes ( 27863252) Mean corpuscular hemoglobin ( 27863252 32888494) Mean corpuscular volume ( 32888494) Red blood cell count ( 27863252 32888494) Serum thyroid-stimulating hormone levels ( 25436638)
Interacting Genes		5 interacting genes: ANP32B HDAC1 HDAC2 HDAC3 TLE3	42 interacting genes: AIM2 APC APP AURKA BAX BCL10 BEND7 BUB1 CHAF1A CSNK2A1 DCC DNTTIP1 ELAVL1 ESR1 FAM217B FAM3A FBXW7 H2AC1 H2BC1 H3C1 H4C1 HNF4A KLF5 KPNA1 KPNA5 MCC MEOX2 MLH3 MYNN PMS2 POLR1A PTEN PTPN12 PTPRJ SDCBP SMAD2 SMARCD1 STK11 TLR2 UCHL5 XPO1 YAF2
Entrez ID		221613	10541
HPRD ID		13653	09803
Ensembl ID		ENSG00000164508	ENSG00000136938
Uniprot IDs		Q96QV6	Q92688
PDB IDs		5GSU 5GT0	2ELL 2RR6 8R1J 8R1L
Enriched GO Terms of Interacting Partners?		Protein Lysine Delactylase Activity Protein Decrotonylase Activity Histone Decrotonylase Activity Histone Deacetylase Activity, Hydrolytic Mechanism Protein Lysine Deacetylase Activity Histone Deacetylase Activity NF-kappaB Binding Protein De-2-hydroxyisobutyrylase Activity Histone Deacetylase Complex Fungiform Papilla Formation Circadian Regulation Of Gene Expression Hair Follicle Placode Formation Deacetylase Activity Histone Deacetylase Binding Circadian Rhythm Eyelid Development In Camera-type Eye Heterochromatin Formation Protein Deacetylation Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Hydrolase Activity, Acting On Carbon-nitrogen (but Not Peptide) Bonds, In Linear Amides NuRD Complex Negative Regulation Of Gene Expression, Epigenetic Negative Regulation Of Myotube Differentiation Chromatin Remodeling DNA-binding Transcription Factor Binding Positive Regulation Of Oligodendrocyte Differentiation Sin3-type Complex Transcription Corepressor Activity Regulation Of Cell Fate Specification Negative Regulation Of Stem Cell Population Maintenance Macromolecule Deacylation Chromatin Organization Negative Regulation Of Apoptotic Process Rhythmic Process Negative Regulation Of Programmed Cell Death Epigenetic Regulation Of Gene Expression Negative Regulation Of Developmental Process Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Protein Export From Nucleus Positive Regulation Of Glial Cell Differentiation Nucleosomal DNA Binding Regulation Of Oligodendrocyte Differentiation Negative Regulation Of Striated Muscle Cell Differentiation Regulation Of Myotube Differentiation Regulation Of Cell Fate Commitment Positive Regulation Of Stem Cell Population Maintenance Transcription Corepressor Binding Embryonic Digit Morphogenesis Negative Regulation Of Multicellular Organismal Process Enzyme Binding	Nucleoplasm Nucleus Chromatin Remodeling Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Cell Cycle Protein Heterodimerization Activity Regulation Of Macromolecule Metabolic Process Developmental Growth DNA Binding Chromatin Organization Regulation Of Ubiquitin-dependent Protein Catabolic Process Regulation Of Multicellular Organismal Process Regulation Of Developmental Process Regulation Of Primary Metabolic Process Positive Regulation Of Catabolic Process Regulation Of Signal Transduction Programmed Cell Death Positive Regulation Of Nucleobase-containing Compound Metabolic Process Cell Death Regulation Of Wnt Signaling Pathway Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Cell Communication DNA Damage Response Regulation Of Signaling Microglia Development Satellite Cell Activation Involved In Skeletal Muscle Regeneration Nucleosome Organization Chromatin Binding Chromosome Organization Protein Localization To Organelle Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Regulation Of Cell Population Proliferation Regulation Of Metabolic Process Regulation Of Mitotic Cell Cycle Regulation Of Protein Catabolic Process Regulation Of Cellular Component Organization Regulation Of Proteolysis Negative Regulation Of Metabolic Process Cytosol Apoptotic Process Regulation Of Gene Expression Kinetochore Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Negative Regulation Of Cell Population Proliferation Structural Constituent Of Chromatin Mismatch Repair Complex Positive Regulation Of RNA Metabolic Process Protein Dephosphorylation
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