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ZBTB12 and RAP1GAP
Number of citations of the paper that reports this interaction (PMID
8939933
)
11
Data Source:
HPRD
(two hybrid, in vitro)
ZBTB12
RAP1GAP
Gene Name
zinc finger and BTB domain containing 12
RAP1 GTPase activating protein
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Nucleus
Golgi Membrane
Cytosol
Membrane
Molecular Function
DNA Binding
Metal Ion Binding
GTPase Activity
GTPase Activator Activity
Protein Binding
Ras GTPase Binding
Protein Homodimerization Activity
Rap GTPase Activator Activity
Biological Process
Transcription, DNA-templated
Regulation Of Transcription, DNA-templated
Signal Transduction
Metabolic Process
Regulation Of Ras GTPase Activity
Positive Regulation Of Rap GTPase Activity
Negative Regulation Of Microvillus Assembly
Pathways
Rap1 signalling
Adaptive Immune System
Drugs
Diseases
GWAS
Hematology traits (
23263863
)
Liver enzyme levels (
18940312
)
Protein-Protein Interactions
2 interactors:
HRAS
RAP1GAP
15 interactors:
BRAF
CDK1
CSNK1G2
DYNC1I1
GNAZ
MAP1LC3B
MAPK6
MEX3B
MLLT4
PFN2
PLK1
PRKACA
RALGDS
RAP1A
ZBTB12
Entrez ID
221527
5909
HPRD ID
15691
02609
Ensembl ID
ENSG00000204366
ENSG00000076864
Uniprot IDs
Q9Y330
P47736
PDB IDs
1SRQ
3BRW
Enriched GO Terms of Interacting Partners
?
Regulation Of Cell Projection Assembly
Negative Regulation Of Microvillus Assembly
Positive Regulation Of Ras GTPase Activity
Positive Regulation Of Rac Protein Signal Transduction
Regulation Of Cell Projection Organization
Regulation Of Microvillus Assembly
Positive Regulation Of MiRNA Metabolic Process
Positive Regulation Of Ruffle Assembly
Regulation Of Ras GTPase Activity
Regulation Of Ras Protein Signal Transduction
Regulation Of MiRNA Metabolic Process
Positive Regulation Of GTPase Activity
Regulation Of Small GTPase Mediated Signal Transduction
Regulation Of GTPase Activity
Negative Regulation Of Rho GTPase Activity
Positive Regulation Of Actin Cytoskeleton Reorganization
Positive Regulation Of Rap GTPase Activity
Regulation Of Ruffle Assembly
Negative Regulation Of Ras GTPase Activity
Regulation Of Rap GTPase Activity
Positive Regulation Of Hydrolase Activity
Regulation Of Rap Protein Signal Transduction
Cellular Senescence
Regulation Of Long-term Neuronal Synaptic Plasticity
Negative Regulation Of GTPase Activity
Regulation Of Synaptic Transmission, GABAergic
Regulation Of Rac Protein Signal Transduction
Regulation Of Actin Cytoskeleton Reorganization
Social Behavior
Positive Regulation Of Wound Healing
Epithelial Tube Branching Involved In Lung Morphogenesis
Positive Regulation Of Catalytic Activity
Positive Regulation Of Ras Protein Signal Transduction
Regulation Of Neuronal Synaptic Plasticity
Positive Regulation Of Rac GTPase Activity
Positive Regulation Of Small GTPase Mediated Signal Transduction
Visual Learning
Visual Behavior
Activation Of MAPKK Activity
Lung Morphogenesis
Regulation Of Intracellular Signal Transduction
Positive Regulation Of DNA Replication
Cell Aging
Regulation Of Cellular Component Organization
Associative Learning
Ephrin Receptor Signaling Pathway
Vascular Endothelial Growth Factor Receptor Signaling Pathway
Neurotrophin TRK Receptor Signaling Pathway
Neurotrophin Signaling Pathway
Peptidyl-serine Phosphorylation
Regulation Of Synaptic Vesicle Exocytosis
Positive Regulation Of Catalytic Activity
Mitotic Nuclear Envelope Disassembly
Regulation Of Synaptic Vesicle Transport
Nuclear Envelope Disassembly
Positive Regulation Of Protein Phosphorylation
Protein Phosphorylation
Positive Regulation Of Phosphorylation
Regulation Of Neurotransmitter Secretion
Activation Of MAPKK Activity
Nuclear Envelope Organization
Positive Regulation Of Protein Modification Process
Positive Regulation Of Transferase Activity
Cellular Response To Growth Factor Stimulus
Activation Of Protein Kinase Activity
Response To Growth Factor
Regulation Of Protein Phosphorylation
Regulation Of Synaptic Transmission
Regulation Of Catalytic Activity
Positive Regulation Of Cellular Protein Metabolic Process
Negative Regulation Of Synaptic Vesicle Exocytosis
Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway
Positive Regulation Of Rap GTPase Activity
Positive Regulation Of Mitotic Cell Cycle
G2/M Transition Of Mitotic Cell Cycle
Nucleus Organization
Positive Regulation Of Protein Metabolic Process
Phosphorylation
Regulation Of Protein Kinase Activity
Intracellular Signal Transduction
Positive Regulation Of ERK1 And ERK2 Cascade
Negative Regulation Of Neurotransmitter Secretion
Regulation Of Rap GTPase Activity
Regulation Of Phosphorylation
Regulation Of Cellular Amino Acid Metabolic Process
Regulation Of Kinase Activity
Negative Regulation Of Neurotransmitter Transport
Regulation Of Rap Protein Signal Transduction
Regulation Of Exocytosis
Positive Regulation Of MAPK Cascade
Fibroblast Growth Factor Receptor Signaling Pathway
Establishment Of Endothelial Barrier
Protein Localization To Chromosome
Enzyme Linked Receptor Protein Signaling Pathway
Positive Regulation Of Protein Kinase Activity
Regulation Of Phosphorus Metabolic Process
Positive Regulation Of Kinase Activity
Tagcloud
?
autophosphorylated
burst
c3g
crk
detrimental
fascin
filamentous
forced
gradual
gtpase
guanine
holds
hyperactivation
imperative
irrespective
labile
microspikes
motile
n17rap1
presumed
protrusions
recruits
releasing
reverses
sh3
unidentified
v12rap1
Tagcloud (Difference)
?
autophosphorylated
burst
c3g
crk
detrimental
fascin
filamentous
forced
gradual
gtpase
guanine
holds
hyperactivation
imperative
irrespective
labile
microspikes
motile
n17rap1
presumed
protrusions
recruits
releasing
reverses
sh3
unidentified
v12rap1
Tagcloud (Intersection)
?