ZBTB12 and ZBTB26

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ZBTB12	ZBTB26
Description		zinc finger and BTB domain containing 12	zinc finger and BTB domain containing 26
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus Nucleoplasm
	Molecular Function	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding	RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Identical Protein Binding Metal Ion Binding Sequence-specific Double-stranded DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process	Negative Regulation Of Transcription By RNA Polymerase II Regulation Of Cytokine Production Regulation Of Immune System Process
Pathways
Drugs
Diseases
GWAS		A body shape index ( 34021172) Asthma ( 31619474) Autism spectrum disorder or schizophrenia ( 28540026) Clostridioides difficle infection ( 33841421) Clostridioides difficle infection in antibiotics-users ( 33841421) Hematology traits ( 23263863) Inflammatory bowel disease ( 28067908) Rosacea symptom severity ( 29771307) Ulcerative colitis ( 28067908) Waist-hip index ( 34021172) Waist-to-hip ratio adjusted for BMI ( 34021172)	Appendicular lean mass ( 33097823) Body mass index ( 26426971) Brain morphology (MOSTest) ( 32665545)
Interacting Genes		5 interacting genes: GRB2 HRAS NCK2 RAP1GAP ZBTB26	35 interacting genes: AXIN1 CARD10 CDC37 CDC7 CYP2W1 DAXX DRC4 DVL3 EHHADH EIF6 GIPC2 HMBOX1 L3MBTL2 LNX1 MORF4L1 MORF4L2 PBK PPL RAD23A RAD54L2 RNF4 SOX5 SUMO1 SUMO1P1 TRAF4 TRIM41 TSGA10 UBE2I ZBTB12 ZBTB34 ZBTB48 ZBTB6 ZBTB9 ZMYM5 ZNF408
Entrez ID		221527	57684
HPRD ID		15691	15692
Ensembl ID		ENSG00000204366	ENSG00000171448
Uniprot IDs		Q9Y330	Q9HCK0
PDB IDs
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Cell-cell Adhesion Positive Regulation Of Cellular Component Organization Phosphotyrosine Residue Binding Positive Regulation Of Protein Polymerization Regulation Of Multicellular Organismal Process Positive Regulation Of Cellular Component Biogenesis Positive Regulation Of Cell Adhesion Regulation Of Actin Cytoskeleton Organization Regulation Of Cytoskeleton Organization Guanyl-nucleotide Exchange Factor Adaptor Activity Endocytosis Regulation Of Actin Filament-based Process Schwann Cell Development ERBB Signaling Pathway Glial Cell Development Regulation Of Cell-cell Adhesion Cellular Response To Ionizing Radiation Positive Regulation Of Actin Filament Polymerization Insulin Receptor Signaling Pathway Cell Surface Receptor Protein Tyrosine Kinase Signaling Pathway Myelination Axon Ensheathment Vesicle Membrane Epidermal Growth Factor Receptor Signaling Pathway Ras Protein Signal Transduction Negative Regulation Of Thyroid Gland Epithelial Cell Proliferation Negative Regulation Of Microvillus Assembly Regulation Of Immune System Process Import Into Cell Regulation Of Actin Filament Polymerization Enzyme-linked Receptor Protein Signaling Pathway Grb2-EGFR Complex GTPase Complex Cellular Response To Glial Cell Derived Neurotrophic Factor Immune System Process Regulation Of Actin Polymerization Or Depolymerization Regulation Of Actin Filament Length Response To Ionizing Radiation Negative Regulation Of Cell Population Proliferation Antigen Receptor-mediated Signaling Pathway Regulation Of Intracellular Signal Transduction Phospholipase C Activator Activity Positive Regulation Of Supramolecular Fiber Organization Regulation Of Cell Adhesion Cellular Response To Radiation Positive Regulation Of Cytoskeleton Organization Response To Glial Cell Derived Neurotrophic Factor Regulation Of Translation Initiation In Response To Endoplasmic Reticulum Stress Positive Regulation Of Protein-containing Complex Assembly Positive Regulation Of Translation In Response To Endoplasmic Reticulum Stress	Regulation Of Primary Metabolic Process PML Body Regulation Of Macromolecule Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Transcription Factor Binding Nucleus Small Protein Activating Enzyme Binding Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process PML Body Organization Nuclear Body Enzyme Binding Double-stranded Telomeric DNA Binding Modification-dependent Protein Catabolic Process Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Protein Sumoylation Zinc Ion Binding Negative Regulation Of RNA Metabolic Process Proteolysis Involved In Protein Catabolic Process Protein Modification By Small Protein Conjugation Protein Tag Activity Regulation Of Ubiquitin-dependent Protein Catabolic Process Identical Protein Binding Positive Regulation Of Metabolic Process DNA Metabolic Process Positive Regulation Of Proteasomal Ubiquitin-dependent Protein Catabolic Process Nuclear Body Organization Positive Regulation Of Macromolecule Metabolic Process Ubiquitin-specific Protease Binding Negative Regulation Of Nucleobase-containing Compound Metabolic Process Cellular Response To Cadmium Ion Regulation Of Proteasomal Protein Catabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Positive Regulation Of JNK Cascade Positive Regulation Of Ubiquitin-dependent Protein Catabolic Process Post-translational Protein Modification Ubiquitin-like Protein Ligase Binding NuA4 Histone Acetyltransferase Complex Presynaptic Cytosol Response To Arsenic-containing Substance Postsynaptic Cytosol Positive Regulation Of Proteasomal Protein Catabolic Process
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