SAMD3 and LMO3

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid)

		SAMD3	LMO3
Description		sterile alpha motif domain containing 3	LIM domain only 3
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component		Nucleus Cytoplasm
	Molecular Function	Protein Binding	Transcription Coactivator Activity Protein Binding Metal Ion Binding DNA-binding Transcription Factor Binding
	Biological Process		Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Fat Cell Differentiation Positive Regulation Of Transcription By RNA Polymerase II Negative Regulation Of ERK1 And ERK2 Cascade Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway
Pathways
Drugs
Diseases
GWAS		Height ( 18391951) Mosquito bite size ( 28199695) Proteinuria in chronic kidney disease ( 26420894)	Barrett's esophagus or Esophageal adenocarcinoma ( 32918910) Barrett's esophagus or esophageal adenocarcinoma x sex interaction (2df test) ( 32918910) Chronotype ( 30696823) Household income (MTAG) ( 31844048) Metastatic colorectal cancer survival in treatment with chemotherapy plus biologics ( 32958699) Smoking initiation ( 33082346) Tourette syndrome ( 30818990) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		8 interacting genes: AKAP9 CFAP206 CFTR FANCG HSPD1 KDM1A LMO3 PRMT1	124 interacting genes: ABI2 ACTMAP AIMP2 AMIGO1 AMOTL2 AVPI1 BANP BCAS2 BEND5 BEND7 BHLHE40 BLZF1 CARD9 CARF CBY2 CCDC33 CCDC85B CCSER1 CDYL2 CEP170P1 CEP57 CEP57L1 CYSRT1 DCDC2 DVL2 DYRK1A FAM131C FBLIM1 FOS GABPB1 GMEB2 GOLGA2 GOLGA6L9 GPATCH2L HMBOX1 HNRNPC HNRNPH1 HNRNPM HOMEZ HSPB2 HSPB2-C11orf52 IKZF1 IL16 INCA1 ITSN1 KANK2 KCTD1 KIF2A KRABD4 KRT31 KRT38 KXD1 LDB1 LDB2 LIMS1 LNPK LPXN LZTS1 LZTS2 MAD1L1 MALSU1 MBD3 MBD3L1 MBIP MDFI MEIS3 MID2 MTUS2 MYOG MYOZ3 NBPF22P NDOR1 NFKBID NHLH2 NIF3L1 NTAQ1 NUTM1 PELO PHC2 PICK1 PNMA1 POU6F2 PPP1R13B PXN QRICH1 RALYL RCN1 RFC5 RFX6 RORA SAMD3 SH2B2 SHISA6 SLAIN1 SP4 TAX1BP1 TCP10L TEPSIN THAP1 TMEM121 TRAPPC2L TRIB3 TRIM23 TRIM54 TUFT1 USP54 VBP1 VMAC VPS28 WASHC1 WWOX ZBTB43 ZBTB8A ZBTB8B ZIM3 ZNF143 ZNF526 ZNF587 ZNF620 ZNF641 ZNF69 ZNF84 ZRANB1 ZSCAN9
Entrez ID		154075	55885
HPRD ID		11530	11832
Ensembl ID		ENSG00000164483	ENSG00000048540
Uniprot IDs		Q8N6K7	Q8TAP4 Q9NYC6
PDB IDs
Enriched GO Terms of Interacting Partners?		Cellular Response To CAMP Response To CAMP Enzyme Binding Response To Purine-containing Compound Cellular Response To Oxygen-containing Compound Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding GATOR1 Complex Binding P53 Binding Mitochondrial Unfolded Protein Response Isotype Switching To IgG Isotypes A Axonemal Microtubule Regulation Of Double-strand Break Repair Via Homologous Recombination Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Protein-folding Chaperone Binding Positive Regulation Of Anion Channel Activity Telomeric Repeat-containing RNA Binding FAD-dependent H3K4me/H3K4me3 Demethylase Activity Positive Regulation Of Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Positive Regulation Of Monoatomic Anion Transport Coated Vesicle Protein Import Into Mitochondrial Intermembrane Space Dendritic Branch Negative Regulation Of Transcription Initiation-coupled Chromatin Remodeling Positive Regulation Of Enamel Mineralization Transepithelial Water Transport Positive Regulation Of Developmental Process Isomerase Activity Cell Maturation Regulation Of DNA Recombination Protein-arginine Omega-N Monomethyltransferase Activity Regulation Of Double-strand Break Repair N-methyltransferase Activity Histone H4R3 Methyltransferase Activity Positive Regulation Of Hemoglobin Biosynthetic Process Peptidyl-arginine Methylation Lipopolysaccharide Receptor Complex Migrasome Apolipoprotein A-I Binding Extrinsic Component Of Postsynaptic Density Membrane MRF Binding Protein Demethylase Activity Positive Regulation Of Tooth Mineralization Chloride Channel Inhibitor Activity Chloride Channel Regulator Activity Regulation Of Enamel Mineralization Membrane Hyperpolarization Organelle Organization Regulation Of Hemoglobin Biosynthetic Process	Protein Binding Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Identical Protein Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Nucleus Regulation Of Transcription By RNA Polymerase II Regulation Of Primary Metabolic Process DNA Binding Regulation Of Macromolecule Biosynthetic Process DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Microtubule Negative Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding
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