SAMD3 and AKAP9

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		SAMD3	AKAP9
Gene Name		sterile alpha motif domain containing 3	A kinase (PRKA) anchor protein 9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component		Pericentriolar Material Golgi Apparatus Centrosome Cytosol Cytoskeleton Voltage-gated Potassium Channel Complex Ciliary Basal Body Intracellular Membrane-bounded Organelle
	Molecular Function	Protein Binding	Receptor Binding Protein Binding Potassium Channel Regulator Activity Protein Complex Scaffold Ion Channel Binding
	Biological Process		G2/M Transition Of Mitotic Cell Cycle Mitotic Cell Cycle Transport Organelle Organization Signal Transduction Synaptic Transmission Spermatogenesis Positive Regulation Of Peptidyl-serine Phosphorylation Sertoli Cell Development Regulation Of Membrane Repolarization Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Cellular Response To CAMP Regulation Of Heart Rate By Cardiac Conduction Positive Regulation Of Potassium Ion Transmembrane Transporter Activity
Pathways			Organelle biogenesis and maintenance Assembly of the primary cilium G2/M Transition CREB phosphorylation through the activation of Ras Regulation of PLK1 Activity at G2/M Transition Anchoring of the basal body to the plasma membrane Cell Cycle, Mitotic Loss of proteins required for interphase microtubule organizationÂ from the centrosome Activation of NMDA receptor upon glutamate binding and postsynaptic events Loss of Nlp from mitotic centrosomes CREB phosphorylation through the activation of CaMKII Centrosome maturation Mitotic G2-G2/M phases Unblocking of NMDA receptor, glutamate binding and activation Neurotransmitter Receptor Binding And Downstream Transmission In The Postsynaptic Cell Recruitment of mitotic centrosome proteins and complexes Ras activation uopn Ca2+ infux through NMDA receptor Post NMDA receptor activation events Transmission across Chemical Synapses
Drugs
Diseases
GWAS		Height ( 18391951)
Protein-Protein Interactions		7 interactors: AKAP9 C6orf165 FANCG HSPD1 KDM1A LMO3 PRMT1	43 interactors: BLZF1 C1orf94 CALM1 CALM2 CALM3 CCP110 CDC5L CEP55 CLIC1 CSNK1D CSNK1E DISC1 FNBP1 GRIN1 HNRNPM IKZF3 KCNQ1 KDM1A MAGEA6 MAGED1 PCNT PKN1 PPP1CA PPP2R1B PPP2R3A PRDM14 PRKAR2A PRKAR2B PRKCE SAMD3 SSX2 SUV39H2 TACC3 TDP2 THAP1 TNIK TRIP10 TSG101 TSNAX TUBGCP3 USHBP1 USO1 WAC
Entrez ID		154075	10142
HPRD ID		11530	04921
Ensembl ID		ENSG00000164483	ENSG00000127914
Uniprot IDs		B4DY20 J3KQK4 Q8N6K7	Q5GIA7 Q6PJH3 Q99996
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Megakaryocyte Differentiation Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Glucocorticoid Receptor Signaling Pathway B Cell Cytokine Production Isotype Switching To IgG Isotypes Regulation Of Primitive Erythrocyte Differentiation Cell Development Positive Regulation Of T Cell Mediated Immune Response To Tumor Cell Regulation Of Myeloid Cell Differentiation System Development Negative Regulation Of Megakaryocyte Differentiation Gonad Development Development Of Primary Sexual Characteristics Multicellular Organismal Development Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Negative Regulation Of Histone H3-K4 Methylation Histone H3-K9 Demethylation Histone H3-K4 Demethylation Anatomical Structure Development Positive Regulation Of Immune Response To Tumor Cell Sex Differentiation Negative Regulation Of Hematopoietic Progenitor Cell Differentiation Positive Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Positive Regulation Of Megakaryocyte Differentiation Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Regulation Of Immune System Process Positive Regulation Of Hormone Biosynthetic Process Positive Regulation Of Potassium Ion Transmembrane Transporter Activity Positive Regulation Of Macrophage Activation Peptidyl-arginine N-methylation Negative Regulation Of Histone H3-K9 Methylation Negative Regulation Of Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Negative Regulation Of DNA Damage Response, Signal Transduction By P53 Class Mediator Developmental Process Histone H4-R3 Methylation Regulation Of Ventricular Cardiac Muscle Cell Membrane Repolarization Chaperone-mediated Protein Complex Assembly Cytokine Production Involved In Immune Response Organelle Organization Negative Regulation Of Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of Peroxisome Proliferator Activated Receptor Signaling Pathway Histone Modification Granulocyte Differentiation Negative Regulation Of Intracellular Signal Transduction Positive Regulation Of Potassium Ion Transmembrane Transport Histone Arginine Methylation Positive Regulation Of Interferon-alpha Production Peptidyl-arginine Methylation Negative Regulation Of Histone Methylation Regulation Of Cell Differentiation	Cell Cycle Activation Of Phospholipase C Activity Positive Regulation Of Phospholipase C Activity Organelle Organization Positive Regulation Of Phospholipase Activity Regulation Of Phospholipase Activity Positive Regulation Of Lipase Activity G2/M Transition Of Mitotic Cell Cycle Regulation Of Cytokinesis Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Cyclic-nucleotide Phosphodiesterase Activity Neurotrophin Signaling Pathway Regulation Of Signaling Energy Reserve Metabolic Process Regulation Of High Voltage-gated Calcium Channel Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Epidermal Growth Factor Receptor Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Response To Amphetamine Blood Coagulation Positive Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Positive Regulation Of Protein Metabolic Process Hemostasis Regulation Of Circadian Rhythm Cell Cycle Process Cellular Response To Fibroblast Growth Factor Stimulus Negative Regulation Of Transporter Activity Response To Fibroblast Growth Factor Positive Regulation Of Protein Kinase Activity Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Regulation Of Protein Metabolic Process Positive Regulation Of Phosphorylation Positive Regulation Of Kinase Activity Positive Regulation Of Cellular Protein Metabolic Process Detection Of Calcium Ion Negative Regulation Of Ion Transmembrane Transport Response To Amine Positive Regulation Of Protein Modification Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Communication By Electrical Coupling Regulation Of Cell Cycle Positive Regulation Of Phosphoprotein Phosphatase Activity Positive Regulation Of Protein Phosphorylation Regulation Of Metabolic Process Negative Regulation Of Transmembrane Transport Mitotic Cell Cycle Positive Regulation Of Transferase Activity Positive Regulation Of Peptidyl-threonine Phosphorylation Positive Regulation Of Protein Autophosphorylation
Tagcloud ?		adjacent androgen androgens antagonistic antagonistically ar btg1 cdca7l cdk6 chip confirming depends find htgp immunoprecipitation mapped position prostate proved publicly ra rar rare responsive restricted retinoic seq tgm4 transactivation	akap450 disrupting eb1 endoplasmic fragmentation functioned golgi immunoprecipitation interacting isoform mapre1 microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Difference) ?		adjacent androgen androgens antagonistic antagonistically ar btg1 cdca7l cdk6 chip confirming depends find htgp mapped position prostate proved publicly ra rar rare responsive restricted retinoic seq tgm4 transactivation	akap450 disrupting eb1 endoplasmic fragmentation functioned golgi interacting isoform mapre1 microtubule microtubules mmg8 myomegalin networks newly nucleation obscure organization organizing participates predominantly reticulum thereby tracking trafficking tubulin variant
Tagcloud (Intersection) ?		immunoprecipitation