FAAP20 and PRDM5

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		FAAP20	PRDM5
Description		FA core complex associated protein 20	PR/SET domain 5
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GO Annotations	Cellular Component	Chromatin Nucleus Nucleoplasm Chromosome Cytosol Nuclear Body Cell Junction Fanconi Anaemia Nuclear Complex	Nucleus Nucleoplasm Nucleolus Nuclear Body
	Molecular Function	Protein Binding Zinc Ion Binding Polyubiquitin Modification-dependent Protein Binding Ubiquitin Binding Metal Ion Binding K63-linked Polyubiquitin Modification-dependent Protein Binding Ubiquitin-modified Protein Reader Activity	Transcription Cis-regulatory Region Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding DNA-binding Transcription Factor Activity Protein Binding Methyltransferase Activity Zinc Ion Binding Transferase Activity Sequence-specific DNA Binding Metal Ion Binding DNA-binding Transcription Factor Binding
	Biological Process	DNA Repair DNA Damage Response Translesion Synthesis Interstrand Cross-link Repair	Negative Regulation Of Transcription By RNA Polymerase II Mitotic Cell Cycle Chromatin Organization Methylation Negative Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II Regulation Of Extracellular Matrix Organization Cellular Response To Leukemia Inhibitory Factor
Pathways		Fanconi Anemia Pathway PKR-mediated signaling
Drugs
Diseases
GWAS		Sedentary behaviour duration ( 30531941) TPE interval (resting) ( 32386560)	F-cell distribution in sickle cell anaemia ( 21326311) Fasting plasma glucose ( 17903298) Hemoglobin levels ( 33491795) Loneliness (multivariate analysis) ( 27629369) Monobrow thickness ( 26926045) Obesity-related traits ( 23251661) Schizophrenia, bipolar disorder or recurrent major depressive disorder ( 34099189) Sensorimotor dexterity ( 31596458)
Interacting Genes		28 interacting genes: ARNT2 BPIFA1 CRX CT55 CTDSP1 DDIT4L DUSP21 FANCF GOLGA6L9 INCA1 KRTAP6-2 KRTAP8-1 LCN2 LMO2 LRP2BP MEOX2 MOB2 NFKBID PFDN5 PIN1 PRDM5 REL REV1 SERTAD1 SERTAD3 TEX11 TRIB3 UBC	7 interacting genes: ADPRS CLCN1 FAAP20 FBXO44 RASD1 TYK2 VIPR1
Entrez ID		199990	11107
HPRD ID		08707	17902
Ensembl ID		ENSG00000162585	ENSG00000138738
Uniprot IDs		F6S8H2 Q6NZ36 Q6ZRT9 Q7Z4P6	Q9NQX1
PDB IDs		2MUQ 2MUR 3WWQ	6XAZ
Enriched GO Terms of Interacting Partners?			ADP-ribosylserine Hydrolase Activity Cellular Response To Superoxide Peptidyl-serine ADP-deribosylation Interleukin-12 Receptor Complex Vasoactive Intestinal Polypeptide Receptor Activity Pituitary Adenylate Cyclase-activating Polypeptide Receptor Activity Poly(ADP-ribose) Glycohydrolase Activity Voltage-gated Chloride Channel Activity Interleukin-23-mediated Signaling Pathway Growth Hormone Receptor Binding Interleukin-10-mediated Signaling Pathway Receptor Complex Extrinsic Component Of Plasma Membrane Positive Regulation Of NK T Cell Proliferation Interleukin-12-mediated Signaling Pathway Interleukin-23 Receptor Complex Type III Interferon-mediated Signaling Pathway Positive Regulation Of NK T Cell Activation Response To Superoxide Response To Oxygen Radical Protein De-ADP-ribosylation O-acetyl-ADP-ribose Deacetylase Activity Ubiquitin-modified Protein Reader Activity Action Potential Propagation Neuronal Action Potential Propagation
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