F2RL3

Description		F2R like thrombin or trypsin receptor 3
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GO Annotations	Cellular Component	Extracellular Region Plasma Membrane Membrane
	Molecular Function	Protease Binding G Protein-coupled Receptor Activity Thrombin-activated Receptor Activity
	Biological Process	Signal Transduction G Protein-coupled Receptor Signaling Pathway Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Blood Coagulation Hemostasis Response To Wounding Platelet Activation Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Platelet Dense Granule Organization Thrombin-activated Receptor Signaling Pathway Platelet Aggregation
Pathways		Peptide ligand-binding receptors G alpha (q) signalling events Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs)
Drugs		Thrombin
Diseases
GWAS		Metabolite levels ( 23823483)
Interacting Genes		2 interacting genes: F2 F2RL2
Entrez ID		9002
HPRD ID		04148
Ensembl ID		ENSG00000127533
Uniprot IDs		Q96RI0
PDB IDs		2ZPK 3QDZ
Enriched GO Terms of Interacting Partners?		Thrombin-activated Receptor Signaling Pathway Ligand-gated Ion Channel Signaling Pathway Positive Regulation Of Peptide Hormone Secretion Platelet Activation Positive Regulation Of Peptide Secretion Positive Regulation Of Insulin Secretion Coagulation Blood Coagulation Hemostasis Receptor Ligand Activity Positive Regulation Of Protein Secretion Positive Regulation Of Hormone Secretion Regulation Of Insulin Secretion Regulation Of Peptide Hormone Secretion Response To Wounding Regulation Of Hormone Secretion Regulation Of Protein Secretion Positive Regulation Of Protein Transport Proteinase-activated Receptor Activity Regulation Of Body Fluid Levels Positive Regulation Of Secretion By Cell Positive Regulation Of Secretion Positive Regulation Of Establishment Of Protein Localization Thrombospondin Receptor Activity Neutrophil-mediated Killing Of Gram-negative Bacterium Thrombin-activated Receptor Activity Positive Regulation Of Protein Localization Regulation Of Protein Transport Positive Regulation Of Phospholipase C-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization Regulation Of Hormone Levels Regulation Of Secretion By Cell Neutrophil-mediated Killing Of Bacterium Cytolysis By Host Of Symbiont Cells Regulation Of Secretion Negative Regulation Of Fibrinolysis Cell Activation Negative Regulation Of Astrocyte Differentiation Regulation Of Fibrinolysis G Protein-coupled Receptor Signaling Pathway Negative Regulation Of Platelet Activation Fibrinolysis Positive Regulation Of Transport Neutrophil Mediated Immunity Regulation Of Protein Localization Positive Regulation Of Collagen Biosynthetic Process Phosphatidylinositol-4,5-bisphosphate Phospholipase C Activity Negative Regulation Of Glial Cell Differentiation Positive Regulation Of Blood Coagulation Positive Regulation Of Coagulation
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