ETV5 and SEZ6L2

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ETV5	SEZ6L2
Gene Name		ets variant 5	seizure related 6 homolog (mouse)-like 2
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Regulatory Region DNA Binding
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Neuromuscular Synaptic Transmission Locomotory Behavior Cell Differentiation Cellular Response To Oxidative Stress Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Male Germ-line Stem Cell Asymmetric Division Regulation Of Synapse Organization Positive Regulation Of Glial Cell Proliferation Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Skeletal Muscle Acetylcholine-gated Channel Clustering
Pathways
Drugs
Diseases
GWAS		Body mass index ( 23563607 19079260 20935630) Menarche (age at onset) ( 21102462) Obesity ( 23563607) Weight ( 19079260)	Anthropometric traits ( 19260139) Response to taxane treatment (placlitaxel) ( 23006423) Systemic lupus erythematosus ( 23273568)
Protein-Protein Interactions		11 interactors: AMH APP AR BRCA1 CCR5 CISH CYP3A5 DHRS7 HOXD9 SEZ6L2 SLC22A2	5 interactors: ETV5 FOXA1 OASL TK1 UNG
Entrez ID		2119	26470
HPRD ID		09035	06686
Ensembl ID		ENSG00000244405	ENSG00000174938
Uniprot IDs		P41161	B7Z5L4 Q6UXD5
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase III Promoter Intracellular Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Intracellular Steroid Hormone Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Histone H4-K20 Methylation Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Preantral Ovarian Follicle Growth Adult Locomotory Behavior Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Integrin Biosynthetic Process Positive Regulation Of Histone H4 Acetylation Alkaloid Catabolic Process Negative Regulation Of Histone H3-K4 Methylation Collateral Sprouting In Absence Of Injury Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Reproductive Process Positive Regulation Of Transcription, DNA-templated Cellular Response To Cytokine Stimulus Regulation Of Integrin Biosynthetic Process Cell Growth Cellular Response To Indole-3-methanol Collateral Sprouting Axon Midline Choice Point Recognition Response To Organic Substance Adult Behavior Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Centriole Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Signaling Response To Cytokine Cell Communication Dosage Compensation By Inactivation Of X Chromosome Axon Choice Point Recognition Oogenesis Stage Positive Regulation Of Cellular Biosynthetic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Protein K6-linked Ubiquitination Gonadal Mesoderm Development Mullerian Duct Regression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation	Fetal Process Involved In Parturition Skeletal Muscle Cell Proliferation Epithelial-mesenchymal Signaling Involved In Prostate Gland Development Prostate Gland Stromal Morphogenesis Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Depyrimidination Male Germ-line Stem Cell Asymmetric Division Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Response To Cortisol Thymidine Metabolic Process Epithelial Cell Maturation Involved In Prostate Gland Development Single Organism Reproductive Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Base-excision Repair, AP Site Formation Deoxyribonucleoside Monophosphate Biosynthetic Process Skeletal Muscle Acetylcholine-gated Channel Clustering Pyrimidine Deoxyribonucleotide Catabolic Process Reproductive Process Positive Regulation Of Neuron Differentiation Epithelial-mesenchymal Cell Signaling Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Glial Cell Proliferation Positive Regulation Of Neurogenesis Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Deoxyribose Phosphate Catabolic Process Parturition Epithelial Cell Differentiation Involved In Prostate Gland Development Response To Steroid Hormone System Development Negative Regulation Of Epithelial To Mesenchymal Transition Gland Development Positive Regulation Of Cell Development Epithelial Cell Maturation Neuromuscular Synaptic Transmission Response To Copper Ion Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Stimulus Regulation Of Neuron Differentiation Nucleotide Metabolic Process Postsynaptic Membrane Organization Nucleobase-containing Compound Metabolic Process Deoxyribonucleotide Catabolic Process Multicellular Organismal Development Neuron Fate Specification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process
Tagcloud ?		3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated exhibits fbln1 filopodia fmn2 gfra2 gpm6a gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi
Tagcloud (Difference) ?		3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated exhibits fbln1 filopodia fmn2 gfra2 gpm6a gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi
Tagcloud (Intersection) ?