ETV5 and HOXD9

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		ETV5	HOXD9
Gene Name		ets variant 5	homeobox D9
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus
	Molecular Function	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Regulatory Region DNA Binding	RNA Polymerase II Regulatory Region Sequence-specific DNA Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Negative Regulation Of Transcription
	Biological Process	Regulation Of Transcription From RNA Polymerase II Promoter Transcription From RNA Polymerase II Promoter Neuromuscular Synaptic Transmission Locomotory Behavior Cell Differentiation Cellular Response To Oxidative Stress Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Male Germ-line Stem Cell Asymmetric Division Regulation Of Synapse Organization Positive Regulation Of Glial Cell Proliferation Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Skeletal Muscle Acetylcholine-gated Channel Clustering	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Single Fertilization Skeletal Muscle Tissue Development Adult Locomotory Behavior Anterior/posterior Pattern Specification Proximal/distal Pattern Formation Mammary Gland Development Embryonic Forelimb Morphogenesis Hindlimb Morphogenesis Positive Regulation Of Transcription From RNA Polymerase II Promoter Embryonic Skeletal System Morphogenesis Peripheral Nervous System Neuron Development
Pathways
Drugs
Diseases
GWAS		Body mass index ( 23563607 19079260 20935630) Menarche (age at onset) ( 21102462) Obesity ( 23563607) Weight ( 19079260)	Magnesium levels ( 20700443)
Protein-Protein Interactions		11 interactors: AMH APP AR BRCA1 CCR5 CISH CYP3A5 DHRS7 HOXD9 SEZ6L2 SLC22A2	9 interactors: BARX1 ETV5 FAIM3 GORAB HMGB1 HOXC9 MEIS1 PBX1 PKNOX1
Entrez ID		2119	3235
HPRD ID		09035	00865
Ensembl ID		ENSG00000244405
Uniprot IDs		P41161	P28356
PDB IDs
Enriched GO Terms of Interacting Partners?		Regulation Of Transcription From RNA Polymerase III Promoter Intracellular Receptor Signaling Pathway Androgen Receptor Signaling Pathway Positive Regulation Of Gene Expression Response To Organic Cyclic Compound Intracellular Steroid Hormone Receptor Signaling Pathway Cell-cell Signaling Positive Regulation Of Histone H4-K20 Methylation Negative Regulation Of Integrin Biosynthetic Process Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Positive Regulation Of Histone H3-K9 Acetylation Preantral Ovarian Follicle Growth Adult Locomotory Behavior Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Integrin Biosynthetic Process Positive Regulation Of Histone H4 Acetylation Alkaloid Catabolic Process Negative Regulation Of Histone H3-K4 Methylation Collateral Sprouting In Absence Of Injury Negative Regulation Of Extrinsic Apoptotic Signaling Pathway Reproductive Process Positive Regulation Of Transcription, DNA-templated Cellular Response To Cytokine Stimulus Regulation Of Integrin Biosynthetic Process Cell Growth Cellular Response To Indole-3-methanol Collateral Sprouting Axon Midline Choice Point Recognition Response To Organic Substance Adult Behavior Positive Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Centriole Replication Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Signaling Response To Cytokine Cell Communication Dosage Compensation By Inactivation Of X Chromosome Axon Choice Point Recognition Oogenesis Stage Positive Regulation Of Cellular Biosynthetic Process Regulation Of Extrinsic Apoptotic Signaling Pathway Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Protein K6-linked Ubiquitination Gonadal Mesoderm Development Mullerian Duct Regression Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of Histone H3-K9 Acetylation Negative Regulation Of Histone H3-K9 Methylation	Immune System Development Positive Regulation Of Transcription From RNA Polymerase II Promoter Immune System Process Transcription, DNA-templated RNA Biosynthetic Process Positive Regulation Of Transcription, DNA-templated System Development Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Biosynthetic Process Positive Regulation Of Gene Expression Regulation Of RNA Metabolic Process Anterior/posterior Pattern Specification Positive Regulation Of Cellular Biosynthetic Process Nucleobase-containing Compound Metabolic Process Spleen Development Multicellular Organismal Development Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Gene Expression Anatomical Structure Development Transcription From RNA Polymerase II Promoter Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process RNA Metabolic Process Cell Differentiation Gene Expression Developmental Process Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Negative Regulation Of Apoptotic Cell Clearance Pattern Specification Process Regulation Of Neuron Differentiation Positive Regulation Of Cellular Metabolic Process Skeletal System Development Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly Hemopoiesis Generation Of Neurons Regulation Of Neurogenesis Embryonic Skeletal System Development Organ Development Negative Regulation Of DNA-templated Transcription, Initiation Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter Neurogenesis Biosynthetic Process Base-excision Repair, DNA Ligation Male Germ-line Stem Cell Asymmetric Division
Tagcloud ?		3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated exhibits fbln1 filopodia fmn2 gfra2 gpm6a gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi	aberrantly aberration adjacent autosomal beadchips bisulfite cholangiocarcinogenesis cholangiocarcinoma cpg eed epigenetically epigenomic false homeobox hoxa9 humanmethylation27 hypermethylated hypermethylation hypomethylated infinium methylomes ontology prc2 profiled pyrosequencing representing sets suz12 trimethylation
Tagcloud (Difference) ?		3t3 alters anchorage arntl2 bfsp2 bmp7 celsr1 confocal deregulated exhibits fbln1 filopodia fmn2 gfra2 gpm6a gpm6b graffi homologs malignancies mulv nih nln oligonucleotide oncogenes parm peri protrusions punctate semi	aberrantly aberration adjacent autosomal beadchips bisulfite cholangiocarcinogenesis cholangiocarcinoma cpg eed epigenetically epigenomic false homeobox hoxa9 humanmethylation27 hypermethylated hypermethylation hypomethylated infinium methylomes ontology prc2 profiled pyrosequencing representing sets suz12 trimethylation
Tagcloud (Intersection) ?