SEZ6L2

Description		seizure related 6 homolog like 2
Image		No pdb structure
GO Annotations	Cellular Component	Endoplasmic Reticulum Endoplasmic Reticulum Membrane Plasma Membrane Membrane Neuronal Cell Body
	Molecular Function
	Biological Process	Adult Locomotory Behavior Cerebellar Purkinje Cell Layer Development Synapse Maturation
Pathways
Drugs
Diseases
GWAS		Alcohol consumption ( 31358974) Alcohol consumption (drinks per week) ( 30643258) Anthropometric traits ( 19260139) Autism spectrum disorder or schizophrenia ( 28540026) Bitter alcoholic beverage consumption ( 31046077) Body fat distribution (arm fat ratio) ( 30664634) Response to taxane treatment (paclitaxel) ( 23006423) Schizophrenia ( 25056061 28991256 29483656) Systemic lupus erythematosus ( 23273568)
Interacting Genes		7 interacting genes: ETV5 FOXA1 MTDH OASL TK1 TOX3 UNG
Entrez ID		26470
HPRD ID		06686
Ensembl ID		ENSG00000174938
Uniprot IDs		A0A087WYL5 A0A0A8K8P7 B7Z5L4 Q6UXD5
PDB IDs
Enriched GO Terms of Interacting Partners?		Germ-line Stem Cell Division Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Positive Regulation Of Neuron Differentiation Nucleus Male Germ-line Stem Cell Asymmetric Division Regulation Of Programmed Cell Death Regulation Of Apoptotic Process Respiratory Basal Cell Differentiation Alveolar Secondary Septum Development Fibrillar Center Positive Regulation Of DNA-binding Transcription Factor Activity Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Positive Regulation Of Dopaminergic Neuron Differentiation Epithelial Cell Maturation Involved In Prostate Gland Development Prostate Gland Stromal Morphogenesis Mesenchymal-epithelial Cell Signaling Involved In Prostate Gland Development DNA Synthesis Involved In Mitotic DNA Replication Thymidine Biosynthetic Process Pyrimidine-containing Compound Metabolic Process Thymidine Kinase Activity Base-excision Repair, AP Site Formation Via Deaminated Base Removal Uracil DNA N-glycosylase Activity Double-stranded RNA Binding 2'-5'-oligoadenylate Synthetase Activity Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Regulation Of Neuron Differentiation Regulation Of DNA-binding Transcription Factor Activity Intercellular Canaliculus Thymidine Metabolic Process Hydrolase Activity, Hydrolyzing N-glycosyl Compounds Positive Regulation Of RNA Metabolic Process Depyrimidination Interleukin-27-mediated Signaling Pathway Skeletal Muscle Acetylcholine-gated Channel Clustering Mesenchymal-epithelial Cell Signaling Epithelial Cell Differentiation Involved In Prostate Gland Development Deoxyribonucleoside Monophosphate Biosynthetic Process Negative Regulation Of Apoptotic Process Regulation Of Dopaminergic Neuron Differentiation Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Single Strand Break Repair Negative Regulation Of Programmed Cell Death Positive Regulation Of RIG-I Signaling Pathway Transcription Cis-regulatory Region Binding Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Nucleobase-containing Compound Metabolic Process Asymmetric Cell Division Dorsal/ventral Neural Tube Patterning Pyrimidine Nucleoside Metabolic Process
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