SEZ6L2 and FOXA1

Number of citations of the paper that reports this interaction (PMID 21988832)
14

Data Source:
BioGRID (two hybrid)

		SEZ6L2	FOXA1
Gene Name		seizure related 6 homolog (mouse)-like 2	forkhead box A1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Endoplasmic Reticulum Membrane Plasma Membrane Integral Component Of Membrane	Nucleus Nucleolus Microvillus
	Molecular Function		Sequence-specific DNA Binding RNA Polymerase II Transcription Factor Activity RNA Polymerase II Core Promoter Proximal Region Sequence-specific DNA Binding Transcription Factor Activity Involved In Positive Regulation Of Transcription DNA Binding Sequence-specific DNA Binding Transcription Factor Activity Transcription Factor Binding Protein Domain Specific Binding Sequence-specific DNA Binding Transcription Regulatory Region DNA Binding
	Biological Process		Negative Regulation Of Transcription From RNA Polymerase II Promoter Chromatin Remodeling Transcription From RNA Polymerase II Promoter Negative Regulation Of Epithelial To Mesenchymal Transition Dorsal/ventral Neural Tube Patterning Response To Estradiol Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Hormone Metabolic Process Glucose Homeostasis Positive Regulation Of Neuron Differentiation Positive Regulation Of Smoothened Signaling Pathway Positive Regulation Of Mitotic Cell Cycle Positive Regulation Of Transcription From RNA Polymerase II Promoter Anatomical Structure Formation Involved In Morphogenesis Neuron Fate Specification Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Epithelial Tube Branching Involved In Lung Morphogenesis Lung Epithelial Cell Differentiation Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Epithelial-mesenchymal Signaling Involved In Prostate Gland Development Prostate Gland Epithelium Morphogenesis Prostate Gland Stromal Morphogenesis Epithelial Cell Maturation Involved In Prostate Gland Development Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Pathways
Drugs
Diseases
GWAS		Anthropometric traits ( 19260139) Response to taxane treatment (placlitaxel) ( 23006423) Systemic lupus erythematosus ( 23273568)
Protein-Protein Interactions		5 interactors: ETV5 FOXA1 OASL TK1 UNG	5 interactors: AR HIST3H3 ONECUT1 SEZ6L2 TLE1
Entrez ID		26470	3169
HPRD ID		06686	03801
Ensembl ID		ENSG00000174938	ENSG00000129514
Uniprot IDs		B7Z5L4 Q6UXD5	B7ZAP5 P55317
PDB IDs
Enriched GO Terms of Interacting Partners?		Fetal Process Involved In Parturition Skeletal Muscle Cell Proliferation Epithelial-mesenchymal Signaling Involved In Prostate Gland Development Prostate Gland Stromal Morphogenesis Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development Depyrimidination Male Germ-line Stem Cell Asymmetric Division Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin Response To Cortisol Thymidine Metabolic Process Epithelial Cell Maturation Involved In Prostate Gland Development Single Organism Reproductive Process Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis Base-excision Repair, AP Site Formation Deoxyribonucleoside Monophosphate Biosynthetic Process Skeletal Muscle Acetylcholine-gated Channel Clustering Pyrimidine Deoxyribonucleotide Catabolic Process Reproductive Process Positive Regulation Of Neuron Differentiation Epithelial-mesenchymal Cell Signaling Pyrimidine Nucleoside Salvage Pyrimidine-containing Compound Salvage Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway Positive Regulation Of Glial Cell Proliferation Positive Regulation Of Neurogenesis Somatic Hypermutation Of Immunoglobulin Genes Somatic Diversification Of Immune Receptors Via Somatic Mutation Deoxyribose Phosphate Catabolic Process Parturition Epithelial Cell Differentiation Involved In Prostate Gland Development Response To Steroid Hormone System Development Negative Regulation Of Epithelial To Mesenchymal Transition Gland Development Positive Regulation Of Cell Development Epithelial Cell Maturation Neuromuscular Synaptic Transmission Response To Copper Ion Regulation Of Intracellular Estrogen Receptor Signaling Pathway Response To Stimulus Regulation Of Neuron Differentiation Nucleotide Metabolic Process Postsynaptic Membrane Organization Nucleobase-containing Compound Metabolic Process Deoxyribonucleotide Catabolic Process Multicellular Organismal Development Neuron Fate Specification Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process	Negative Regulation Of Integrin Biosynthetic Process Transcription From RNA Polymerase II Promoter Negative Regulation Of Signal Transduction Positive Regulation Of Integrin Biosynthetic Process Negative Regulation Of Signaling Regulation Of Integrin Biosynthetic Process Positive Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription From RNA Polymerase III Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Negative Regulation Of Anoikis Gland Development Nitrogen Compound Metabolic Process Regulation Of Anoikis Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase III Promoter RNA Biosynthetic Process Regulation Of Signal Transduction Androgen Receptor Signaling Pathway Regulation Of Establishment Of Protein Localization To Plasma Membrane Organ Development Spleen Development Regulation Of Signaling Negative Regulation Of I-kappaB Kinase/NF-kappaB Signaling Negative Regulation Of Apoptotic Process Negative Regulation Of Programmed Cell Death Regulation Of Protein Localization To Plasma Membrane RNA Metabolic Process Endocrine Pancreas Development Negative Regulation Of Cell Death Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Gene Expression Intracellular Steroid Hormone Receptor Signaling Pathway Prostate Gland Development Negative Regulation Of Transforming Growth Factor Beta Receptor Signaling Pathway Cellular Macromolecule Biosynthetic Process Telomere Maintenance Macromolecule Biosynthetic Process
Tagcloud ?			3a 3b advance brca1 chip deficent deoxycitydine deposit dnmt dnmt3b doi downregulation ezh2 familial gsk126 h3k27me3 hypermethylation impairs likewise maintains methylation methyltransferase methyltransferases mmecs notion onc publication reconstituted reconstitution
Tagcloud (Difference) ?			3a 3b advance brca1 chip deficent deoxycitydine deposit dnmt dnmt3b doi downregulation ezh2 familial gsk126 h3k27me3 hypermethylation impairs likewise maintains methylation methyltransferase methyltransferases mmecs notion onc publication reconstituted reconstitution
Tagcloud (Intersection) ?