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SEZ6L2 and OASL
Number of citations of the paper that reports this interaction (PMID
21988832
)
14
Data Source:
BioGRID
(two hybrid)
SEZ6L2
OASL
Gene Name
seizure related 6 homolog (mouse)-like 2
2-5-oligoadenylate synthetase-like
Image
No pdb structure
Gene Ontology Annotations
Cellular Component
Endoplasmic Reticulum Membrane
Plasma Membrane
Integral Component Of Membrane
Nucleolus
Cytoplasm
Cytosol
Membrane
Molecular Function
2'-5'-oligoadenylate Synthetase Activity
DNA Binding
Double-stranded RNA Binding
ATP Binding
Poly(A) RNA Binding
Thyroid Hormone Receptor Binding
Biological Process
Metabolic Process
Response To Virus
Cytokine-mediated Signaling Pathway
Negative Regulation Of Viral Genome Replication
Defense Response To Virus
Interferon-gamma-mediated Signaling Pathway
Type I Interferon Signaling Pathway
Pathways
Interferon gamma signaling
Interferon Signaling
Cytokine Signaling in Immune system
Interferon alpha/beta signaling
Drugs
Diseases
GWAS
Anthropometric traits (
19260139
)
Response to taxane treatment (placlitaxel) (
23006423
)
Systemic lupus erythematosus (
23273568
)
C-reactive protein (
22939635
)
Cardiovascular disease risk factors (
21943158
)
N-glycan levels (
21203500
)
Protein-Protein Interactions
5 interactors:
ETV5
FOXA1
OASL
TK1
UNG
3 interactors:
MBD1
SEZ6L2
THRA
Entrez ID
26470
8638
HPRD ID
06686
04473
Ensembl ID
ENSG00000174938
ENSG00000135114
Uniprot IDs
B7Z5L4
Q6UXD5
Q15646
PDB IDs
1WH3
Enriched GO Terms of Interacting Partners
?
Fetal Process Involved In Parturition
Skeletal Muscle Cell Proliferation
Epithelial-mesenchymal Signaling Involved In Prostate Gland Development
Prostate Gland Stromal Morphogenesis
Secretory Columnal Luminar Epithelial Cell Differentiation Involved In Prostate Glandular Acinus Development
Depyrimidination
Male Germ-line Stem Cell Asymmetric Division
Positive Regulation Of Cell-cell Adhesion Mediated By Cadherin
Response To Cortisol
Thymidine Metabolic Process
Epithelial Cell Maturation Involved In Prostate Gland Development
Single Organism Reproductive Process
Positive Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Regulation Of Branching Involved In Mammary Gland Duct Morphogenesis
Base-excision Repair, AP Site Formation
Deoxyribonucleoside Monophosphate Biosynthetic Process
Skeletal Muscle Acetylcholine-gated Channel Clustering
Pyrimidine Deoxyribonucleotide Catabolic Process
Reproductive Process
Positive Regulation Of Neuron Differentiation
Epithelial-mesenchymal Cell Signaling
Pyrimidine Nucleoside Salvage
Pyrimidine-containing Compound Salvage
Positive Regulation Of Intracellular Steroid Hormone Receptor Signaling Pathway
Positive Regulation Of Glial Cell Proliferation
Positive Regulation Of Neurogenesis
Somatic Hypermutation Of Immunoglobulin Genes
Somatic Diversification Of Immune Receptors Via Somatic Mutation
Deoxyribose Phosphate Catabolic Process
Parturition
Epithelial Cell Differentiation Involved In Prostate Gland Development
Response To Steroid Hormone
System Development
Negative Regulation Of Epithelial To Mesenchymal Transition
Gland Development
Positive Regulation Of Cell Development
Epithelial Cell Maturation
Neuromuscular Synaptic Transmission
Response To Copper Ion
Regulation Of Intracellular Estrogen Receptor Signaling Pathway
Response To Stimulus
Regulation Of Neuron Differentiation
Nucleotide Metabolic Process
Postsynaptic Membrane Organization
Nucleobase-containing Compound Metabolic Process
Deoxyribonucleotide Catabolic Process
Multicellular Organismal Development
Neuron Fate Specification
Heterocycle Metabolic Process
Cellular Aromatic Compound Metabolic Process
Negative Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Positive Regulation Of Female Receptivity
Negative Regulation Of DNA-templated Transcription, Initiation
Negative Regulation Of Transcription Initiation From RNA Polymerase II Promoter
Regulation Of RNA Polymerase II Transcriptional Preinitiation Complex Assembly
Female Courtship Behavior
Regulation Of Thyroid Hormone Mediated Signaling Pathway
Regulation Of Female Receptivity
Female Mating Behavior
Type I Pneumocyte Differentiation
Transcription From RNA Polymerase II Promoter
Cytoplasmic Sequestering Of Transcription Factor
Cytoplasmic Sequestering Of Protein
Cartilage Condensation
Regulation Of DNA-templated Transcription, Initiation
Thyroid Gland Development
Negative Regulation Of Transcription, DNA-templated
Negative Regulation Of Nucleic Acid-templated Transcription
Negative Regulation Of RNA Biosynthetic Process
Positive Regulation Of Myotube Differentiation
Mating Behavior
Regulation Of Myeloid Cell Apoptotic Process
Negative Regulation Of Gene Expression
Negative Regulation Of Biosynthetic Process
Negative Regulation Of Transcription Factor Import Into Nucleus
Mating
Response To Cold
Regulation Of Lipid Catabolic Process
Regulation Of Myotube Differentiation
Lung Epithelial Cell Differentiation
Positive Regulation Of Striated Muscle Cell Differentiation
Lung Cell Differentiation
Lung Epithelium Development
Negative Regulation Of Protein Import Into Nucleus
Negative Regulation Of Protein Localization To Nucleus
Positive Regulation Of Muscle Cell Differentiation
Negative Regulation Of Intracellular Protein Transport
Regulation Of Transcription Factor Import Into Nucleus
Negative Regulation Of Cellular Metabolic Process
Regulation Of Striated Muscle Cell Differentiation
Erythrocyte Differentiation
Steroid Hormone Mediated Signaling Pathway
Erythrocyte Homeostasis
Transcription, DNA-templated
Negative Regulation Of Intracellular Transport
RNA Biosynthetic Process
Negative Regulation Of Protein Complex Assembly
Myeloid Cell Homeostasis
Hormone-mediated Signaling Pathway
Maintenance Of Protein Location In Cell
Tagcloud
?
4a
abrogate
adaptor
altogether
antiviral
argue
cardif
ccl5
cleaving
compromised
counteracts
cxcl10
cxcl11
cxcl9
ectopically
evasion
hcv
hepatocytes
ifnbeta
il28a
il29
impairing
innate
irf3
isg15
isg56
isgs
ns3
polyprotein
Tagcloud (Difference)
?
4a
abrogate
adaptor
altogether
antiviral
argue
cardif
ccl5
cleaving
compromised
counteracts
cxcl10
cxcl11
cxcl9
ectopically
evasion
hcv
hepatocytes
ifnbeta
il28a
il29
impairing
innate
irf3
isg15
isg56
isgs
ns3
polyprotein
Tagcloud (Intersection)
?