EPOR and SYP

Number of citations of the paper that reports this interaction (PMID 7534299)
24

Data Source:
BioGRID (pull down)

		EPOR	SYP
Gene Name		erythropoietin receptor	synaptophysin
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Integral Component Of Plasma Membrane	Synaptic Vesicle Cell Junction Integral Component Of Synaptic Vesicle Membrane Synaptic Vesicle Membrane Presynaptic Membrane Neuron Projection Protein Complex Neuron Projection Terminus Presynaptic Active Zone Excitatory Synapse
	Molecular Function	Erythropoietin Receptor Activity Protein Binding Identical Protein Binding	Transporter Activity Cholesterol Binding Syntaxin-1 Binding Protein Complex Binding SH2 Domain Binding Identical Protein Binding Protein Self-association
	Biological Process	Signal Transduction Brain Development Heart Development Erythropoietin-mediated Signaling Pathway Decidualization	Endocytosis Synaptic Vesicle Maturation Regulation Of Neuronal Synaptic Plasticity Regulation Of Long-term Neuronal Synaptic Plasticity Regulation Of Short-term Neuronal Synaptic Plasticity Synaptic Vesicle Membrane Organization Cellular Response To Organic Substance Regulation Of Opioid Receptor Signaling Pathway
Pathways
Drugs		Darbepoetin alfa Epoetin alfa 3,5 DIBROMOTYROSINE Peginesatide
Diseases
GWAS
Protein-Protein Interactions		36 interactors: ATXN2L CBL CISH CRKL CSF2RB EPO GAB1 GAB2 GNAI1 GNB2L1 GRAP GRB2 INPP5D IRS2 JAK2 KIT KITLG KLK3 LYN MAPK1 MAPK3 MST1R PIK3R1 PLCG1 PLCG2 PTPN11 PTPN6 SH2B2 SHC1 SOCS2 SOCS3 STAT5A STAT5B SYK SYP VAV1	6 interactors: AP1G1 EPOR GRB2 SIAH1 SIAH2 VAMP2
Entrez ID		2057	6855
HPRD ID		00587	02435
Ensembl ID		ENSG00000187266	ENSG00000102003
Uniprot IDs		P19235	B7Z359 P08247
PDB IDs		1CN4 1EBA 1EBP 1EER 1ERN 2JIX
Enriched GO Terms of Interacting Partners?		Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Growth Hormone Receptor Signaling Pathway Cellular Response To Growth Hormone Stimulus JAK-STAT Cascade Involved In Growth Hormone Signaling Pathway Response To Growth Hormone Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Immune Response Response To Organic Substance Immune Response-regulating Signaling Pathway Fc-epsilon Receptor Signaling Pathway Cellular Response To Peptide Hormone Stimulus Intracellular Signal Transduction Cellular Response To Peptide Regulation Of Kinase Activity Fc Receptor Signaling Pathway Response To Peptide Hormone Regulation Of Body Fluid Levels JAK-STAT Cascade Response To Peptide Cellular Response To Organic Substance Cell Surface Receptor Signaling Pathway Positive Regulation Of Signal Transduction Blood Coagulation Regulation Of Immune System Process Hemostasis Innate Immune Response Defense Response Cellular Response To Hormone Stimulus Cellular Response To Organonitrogen Compound Regulation Of Signaling Immune System Process Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Signal Transduction Regulation Of Protein Kinase Activity ERBB Signaling Pathway Fibroblast Growth Factor Receptor Signaling Pathway Regulation Of Phosphorylation Response To Hormone Cellular Response To Fibroblast Growth Factor Stimulus Response To Fibroblast Growth Factor Response To Wounding Wound Healing Neurotrophin TRK Receptor Signaling Pathway Regulation Of Phosphorus Metabolic Process Immune Response Neurotrophin Signaling Pathway Regulation Of Intracellular Signal Transduction Signaling Cell Communication	Axon Guidance Post-Golgi Vesicle-mediated Transport Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Chemotaxis Neuron Projection Morphogenesis Response To External Stimulus Erythropoietin-mediated Signaling Pathway Positive Regulation Of Natural Killer Cell Degranulation Cell Morphogenesis Involved In Differentiation Regulation Of Exocytosis Golgi To Lysosome Transport Eosinophil Degranulation Neuron Projection Development Cell Projection Morphogenesis Cell Part Morphogenesis Cellular Response To Erythropoietin Placenta Development Nervous System Development Vesicle Organization Cellular Response To Insulin Stimulus Neuron Development Cell Morphogenesis Response To Stimulus Golgi Vesicle Transport Golgi To Vacuole Transport Neuron Differentiation Cell Projection Organization Pigment Granule Maturation Endosome To Melanosome Transport Response To Insulin Single Organism Reproductive Process Positive Regulation Of Cell Activation Cellular Response To Peptide Hormone Stimulus Cellular Pigment Accumulation Branching Involved In Labyrinthine Layer Morphogenesis Locomotion Cellular Response To Peptide Reproductive Process Developmental Process Regulation Of Signaling Regulation Of Vesicle-mediated Transport Vesicle-mediated Transport Regulation Of Lymphocyte Activation Movement Of Cell Or Subcellular Component Positive Regulation Of Natural Killer Cell Mediated Cytotoxicity Generation Of Neurons Cell Differentiation Positive Regulation Of Regulated Secretory Pathway
Tagcloud ?		actual agonist angstrom antagonist apart configuration crystal dimer efficiency erythropoietin far formed hematopoietic homodimerization insights interact ligands mimetic organization peptide permit plasticity preformed recognition resolution spanning thought unliganded	2h3 accessory aggregation associate coprecipitated dephosphorylated epsilonri fc homology ige immunoreceptor mast phosphatases phosphorylated precipitated ptp1 ptp1c ptp1d ptp2 ptp2c rbl reciprocal sh shp src syk synthetic tyrosine unlike
Tagcloud (Difference) ?		actual agonist angstrom antagonist apart configuration crystal dimer efficiency erythropoietin far formed hematopoietic homodimerization insights interact ligands mimetic organization peptide permit plasticity preformed recognition resolution spanning thought unliganded	2h3 accessory aggregation associate coprecipitated dephosphorylated epsilonri fc homology ige immunoreceptor mast phosphatases phosphorylated precipitated ptp1 ptp1c ptp1d ptp2 ptp2c rbl reciprocal sh shp src syk synthetic tyrosine unlike
Tagcloud (Intersection) ?