ENTPD3 and TMEM106A

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		ENTPD3	TMEM106A
Description		ectonucleoside triphosphate diphosphohydrolase 3	transmembrane protein 106A
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Plasma Membrane Membrane	Plasma Membrane Membrane
	Molecular Function	Nucleotide Binding Apyrase Activity GDP Phosphatase Activity Protein Binding ATP Binding Hydrolase Activity Nucleoside Diphosphate Phosphatase Activity Ribonucleoside Triphosphate Phosphatase Activity UDP Phosphatase Activity	Protein Binding
	Biological Process	Nucleoside Diphosphate Catabolic Process Nucleoside Triphosphate Catabolic Process	Immune System Process Glycoprotein Biosynthetic Process Positive Regulation Of Interleukin-1 Beta Production Positive Regulation Of Interleukin-6 Production Positive Regulation Of Tumor Necrosis Factor Production Macrophage Activation Positive Regulation Of Canonical NF-kappaB Signal Transduction Positive Regulation Of MAPK Cascade Innate Immune Response Positive Regulation Of MHC Class II Biosynthetic Process Positive Regulation Of Nitric Oxide Metabolic Process
Pathways		Phosphate bond hydrolysis by NTPDase proteins
Drugs
Diseases
GWAS		Eosinophil percentage of white cells ( 32888494) Neuroticism ( 29255261)	Blood protein levels ( 30072576)
Interacting Genes		16 interacting genes: ARL13B CREB3L1 ERGIC3 FAM209A FNDC9 GGT6 GPA33 IFNGR2 LEUTX LHFPL5 LMNA MUC1 PTPN5 STX2 SYNE4 TMEM106A	12 interacting genes: ARF1 ENTPD3 ERG28 GJB2 GOSR2 IGFBP5 RHOU TMEM107 TMEM128 TMEM86B TNMD TSPAN4
Entrez ID		956	113277
HPRD ID		16014	11315
Ensembl ID		ENSG00000168032	ENSG00000184988
Uniprot IDs		O75355	B7Z779 Q96A25
PDB IDs
Enriched GO Terms of Interacting Partners?		Establishment Of Apical/basal Cell Polarity Establishment Of Monopolar Cell Polarity Establishment Or Maintenance Of Monopolar Cell Polarity Membrane Polarized Epithelial Cell Differentiation Establishment Of Epithelial Cell Apical/basal Polarity Establishment Of Epithelial Cell Polarity
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