EBAG9 and MGLL

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		EBAG9	MGLL
Description		estrogen receptor binding site associated antigen 9	monoglyceride lipase
Image		No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Secretory Granule	Cytoplasm Endoplasmic Reticulum Membrane Cytosol Plasma Membrane Membrane
	Molecular Function	Protein Binding Peptidase Activator Activity Involved In Apoptotic Process	Phosphatidylcholine Lysophospholipase Activity Protein Binding Hydrolase Activity Protein Homodimerization Activity Monoacylglycerol Lipase Activity Carboxylic Ester Hydrolase Activity
	Biological Process	Regulation Of Cell Growth T Cell Mediated Cytotoxicity Apoptotic Process Adaptive Immune Memory Response Involving T Cells And B Cells	Lipid Metabolic Process Fatty Acid Metabolic Process Fatty Acid Biosynthetic Process Inflammatory Response Regulation Of Signal Transduction Lipid Catabolic Process Arachidonate Metabolic Process Triglyceride Catabolic Process Acylglycerol Catabolic Process Regulation Of Inflammatory Response Regulation Of Sensory Perception Of Pain Monoacylglycerol Catabolic Process Regulation Of Endocannabinoid Signaling Pathway
Pathways		Estrogen-dependent gene expression	Acyl chain remodeling of DAG and TAG Triglyceride catabolism Arachidonate production from DAG MLL4 and MLL3 complexes regulate expression of PPARG target genes in adipogenesis and hepatic steatosis
Drugs
Diseases
GWAS		Metabolite levels ( 23823483) Nicotine dependence and major depression (severity of comorbidity) ( 30287806)	Amyotrophic lateral sclerosis (sporadic) ( 24529757) Carotid intima media thickness x smoking interaction ( 32117412) Femur bone mineral density x serum urate levels interaction ( 34046847) Pars triangularis volume ( 31530798) Refractive error ( 32231278)
Interacting Genes		30 interacting genes: ACSL5 APOL2 BNIP3 C14orf180 CFHR5 CIAO2A CLEC4G CLN6 GOLPH3 GOLPH3L MGLL NEDD4 OR10AG1 ORMDL1 PEX16 PRAF2 REEP6 SLC30A2 SLC35A1 SLC35A4 SLC35B4 SNAPIN STX1A STX2 STX3 TMEM107 TPRG1 TRAF3IP3 VAPA VAPB	26 interacting genes: ADRB2 AQP6 CD79A CHGB COQ9 EBAG9 FAM209A FCER1G GEM GOLT1A GPR152 HSD17B13 HTR4 LMNA LTB4R2 MSRB3 PEX12 SDCBP SLC10A6 SLC18A1 SLC66A2 SLC71A2 SLC7A14 STOM TMEM35A TMX2
Entrez ID		9166	11343
HPRD ID		05775	17574
Ensembl ID		ENSG00000147654	ENSG00000074416
Uniprot IDs		O00559	A0A0C4DFN3 B2ZGL7 Q99685
PDB IDs			3HJU 3JW8 3JWE 3PE6 4UUQ 5ZUN 6AX1 6BQ0 7L4T 7L4U 7L4W 7L50 7PRM 7ZPG 8AQF 8PTC 8PTQ 8PTR 8RVF 9F8A 9F8B 9F8C 9F8D 9FY5
Enriched GO Terms of Interacting Partners?		Membrane Membrane Docking Vesicle Organization Organelle Localization By Membrane Tethering Vesicle Budding From Membrane Pyrimidine Nucleotide-sugar Transmembrane Transport Endoplasmic Reticulum Membrane Nucleotide-sugar Transmembrane Transport Membrane Organization SNARE Binding Membrane Fusion FFAT Motif Binding Protein Targeting To Golgi Apparatus Golgi Membrane Golgi Vesicle Budding Cargo Adaptor Activity Cellular Localization Vesicle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Organelle Membrane Fusion SNAP Receptor Activity Endoplasmic Reticulum Localization Protein Transport SNARE Complex Organelle Fusion Organophosphate Ester Transport Golgi Cisterna Organelle Localization Intracellular Protein Localization Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Intracellular Transport Host-mediated Activation Of Viral Genome Replication Organelle Organization Vesicle Fusion To Plasma Membrane Endoplasmic Reticulum Organization Host-mediated Perturbation Of Viral Genome Replication Sphingomyelin Biosynthetic Process Vesicle Docking Establishment Of Localization In Cell Host-mediated Suppression Of Viral Genome Replication Establishment Of Protein Localization Intracellular Chemical Homeostasis Intracellular Protein Transport Synaptic Vesicle Membrane Organization Carbohydrate Derivative Transport Zymogen Granule Membrane Exocytosis
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