EBAG9 and REEP6

Number of citations: 50 (PubMedID 32296183)
Data Source: BioGRID (two hybrid)

		EBAG9	REEP6
Name		estrogen receptor binding site associated antigen 9	receptor accessory protein 6
Structure		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Golgi Apparatus Membrane Secretory Granule	Photoreceptor Inner Segment Nucleus Endoplasmic Reticulum Endoplasmic Reticulum Membrane Membrane Clathrin-coated Vesicle Membrane Cytoplasmic Vesicle
	Molecular Function	Protein Binding Peptidase Activator Activity Involved In Apoptotic Process	Protein Binding
	Biological Process	Regulation Of Cell Growth T Cell Mediated Cytotoxicity Apoptotic Process Adaptive Immune Memory Response Involving T Cells And B Cells	Endoplasmic Reticulum Organization Regulation Of Intracellular Transport Detection Of Light Stimulus Involved In Visual Perception
Pathways		Estrogen-dependent gene expression	None
GWAS		Metabolite levels ( 23823483 ) Nicotine dependence and major depression (severity of comorbidity) ( 30287806 )	No GWAS studies recorded
Novel Interactors		None recorded	5 novel interactors: ADAT3 IZUMO4 SCAMP4 TMEM259 ZNF554
Interacting Genes		30 interacting genes: ACSL5 APOL2 BNIP3 C14orf180 CFHR5 CIAO2A CLEC4G CLN6 GOLPH3 GOLPH3L MGLL NEDD4 OR10AG1 ORMDL1 PEX16 PRAF2 REEP6 SLC30A2 SLC35A1 SLC35A4 SLC35B4 SNAPIN STX1A STX2 STX3 TMEM107 TPRG1 TRAF3IP3 VAPA VAPB	46 interacting genes: AQP6 ARL6IP1 ATP5PF BIK CD79A CDC37 CERT1 COQ8A CYB561 CYB5R3 EBAG9 FHIP1B GJA8 GORASP2 GPR152 HMBOX1 HSD17B13 KRTAP3-1 LEPROTL1 LITAF LMNA LNX1 MIEF2 NDRG4 NTAQ1 PICK1 PTPN9 RPS20 SDCBP SLC30A8 SNX1 SNX11 SNX15 SNX8 SPG21 STING1 SYT16 TIMMDC1 TLCD4 TMED8 TMEM143 TMPPE TNS2 TXN2 WIPI2 ZFYVE21
Entrez ID		9166	92840
HPRD ID		05775	16629
Ensembl ID		ENSG00000147654	ENSG00000115255
Uniprot IDs		O00559	A0A1L5BXV2 Q96HR9
PDB IDs		Not available	Not available
GO Terms Enriched among Interactors		Membrane Membrane Docking Vesicle Organization Organelle Localization By Membrane Tethering Vesicle Budding From Membrane Pyrimidine Nucleotide-sugar Transmembrane Transport Endoplasmic Reticulum Membrane Nucleotide-sugar Transmembrane Transport Membrane Organization SNARE Binding Membrane Fusion FFAT Motif Binding Protein Targeting To Golgi Apparatus Golgi Membrane Golgi Vesicle Budding Cargo Adaptor Activity Cellular Localization Vesicle Fusion COPII-coated Vesicle Budding Endoplasmic Reticulum-plasma Membrane Tethering Pyrimidine Nucleotide-sugar Transmembrane Transporter Activity Organelle Membrane Fusion SNAP Receptor Activity Endoplasmic Reticulum Localization Protein Transport SNARE Complex Organelle Fusion Organophosphate Ester Transport Golgi Cisterna Organelle Localization Intracellular Protein Localization Vesicle-mediated Transport Synaptic Vesicle Fusion To Presynaptic Active Zone Membrane Intracellular Transport Host-mediated Activation Of Viral Genome Replication Organelle Organization Vesicle Fusion To Plasma Membrane Endoplasmic Reticulum Organization Host-mediated Perturbation Of Viral Genome Replication Sphingomyelin Biosynthetic Process Vesicle Docking Establishment Of Localization In Cell Host-mediated Suppression Of Viral Genome Replication Establishment Of Protein Localization Intracellular Chemical Homeostasis Intracellular Protein Transport Synaptic Vesicle Membrane Organization Carbohydrate Derivative Transport Zymogen Granule Membrane Exocytosis	Lipid Binding Establishment Of Protein Localization Identical Protein Binding Membrane